anti-Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) Antikörper

HLA-DMB belongs to the HLA class II beta chain paralogues. Zusätzlich bieten wir Ihnen HLA-DMB Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
HLA-DMB 3109 P28068
HLA-DMB 294273  
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Top anti-HLA-DMB Antikörper auf antikoerper-online.de

Showing 10 out of 70 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of HLA-DMB Antibody (Center) in Ramos cell line lysates (35ug/lane). This demonstrates the HLA-DMB antibody detected the HLA-DMB protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti-HLA DMB antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Human Kaninchen Unkonjugiert IHC, WB Host: Rabbit Target Name: HLA-DMB Sample Type: Human Placenta Antibody Dilution: 1.0ug/ml Rabbit Anti-HLA-DMB Antibody Catalog Number: ARP63380_P050 Formalin Fixed Paraffin Embedded Tissue: Human heart Tissue Observed Staining: Plasma membrane in intercalated disk Primary Antibody Concentration: 1:100 Other Working Concentrations: N/A Secondary Antibody: Donkey anti-Rabbit-Cy3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 - 2.0 sec 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
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Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (37.62 KDa) . 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$430.00
Details
Human Kaninchen Unkonjugiert WB HLA-DMB Antibody (Center)  western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the HLA-DMB antibody detected the HLA-DMB protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert WB HLA-DMB Antibody (Center)  western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the HLA-DMB antibody detected the HLA-DMB protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB WB Image Western Blot analysis of HLA-DMB expression in transfected 293T cell line by HLA-DMB polyclonal antibody. A:Non-transfected lysate. B:HLA-DMB transfected lysate. 12% SDS PAGE antibody diluted at 1:500 IHC-P Image Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using HLA-DMB, antibody at 1:250 dilution. 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: HLA DMB Antibody [NBP1-31138] - Expression in transfected 293T cell line by HLA-DMB polyclonal antibody. A: Non-transfected lysate. B: HLA-DMB transfected lysate. 12% SDS PAGE, antibody diluted at 1:500. Immunohistochemistry-Paraffin: HLA DMB Antibody [NBP1-31138] - Paraffin-embedded Colon ca, using antibody at 1:250 dilution. 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$447.56
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of Raji cells, using HLA-DMB antibody. Immunohistochemistry of paraffin-embedded human stomach using HLA-DMB antibody at dilution of 1:100 (40x lens). 100 μL Anmelden zum Anzeigen 16 Days
$323.13
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry-Paraffin: HLA DMB Antibody [NBP1-85326] - Staining of human lymph node shows strong cytoplasmic positivity in reaction center cells and lymphoid cells outside reaction centra. Western Blot: HLA DMB Antibody [NBP1-85326] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted).Lane 5: Human liver tissue.Lane 6: Human tonsil tissue 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
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HLA-DMB Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human
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Rat (Rattus)


Am meisten referenzierte anti-HLA-DMB Antikörper

  1. Human Monoclonal HLA-DMB Primary Antibody für ELISA, WB - ABIN561269 : Callahan, Nagymanyoki, Bonome, Johnson, Litkouhi, Sullivan, Hirsch, Matulonis, Liu, Birrer, Berkowitz, Mok: Increased HLA-DMB expression in the tumor epithelium is associated with increased CTL infiltration and improved prognosis in advanced-stage serous ovarian cancer. in Clinical cancer research : an official journal of the American Association for Cancer Research 2008 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen HLA-DMB Interaktionspartner

Human Major Histocompatibility Complex, Class II, DM beta (HLA-DMB) Interaktionspartner

  1. Data suggest that antigen processing by MHC class II HLA-DMB antigen is a target pathway in the pathogenesis of HIV-related Kaposi's sarcoma.

  2. DMA (zeige HLA-DMA Antikörper)*01:01 (69.35%) and DMB*01:01 (52.5%) alleles were more frequent in Chinese Hans

  3. Overexpression of HLA-DM at the plasma membrane of dendritic cells improves quantitatively, but also qualitatively, the presentation of CD4 (zeige CD4 Antikörper)-expressing T cell epitopes in cellular vaccine therapies for cancer.

  4. HLA-DM mediates a noncooperative release of prebound influenza virus hemagglutinin (zeige HA Antikörper) peptides from wild-type HLA-DR1 (zeige DR1 Antikörper) by destabilizing the beta81 hydrogen (H-)bond, since a similar phenomenon is observed when this H-bond is absent.

  5. HLA DMA (zeige HLA-DMA Antikörper) and DMB show no association with rheumatoid arthritis in US Caucasians.

  6. HLA-DMB may play an important role in pathogenesis of type 1 diabetes, and clinical status heterogeneity of type 1 diabetes may be related to genetic mechanism.

  7. glycosylation promotes, but is not essential for, DMalphabeta ER exit; single DMalpha chains cannot fully oxidize without DMbeta (zeige GPHb5 Antikörper), while DMbeta (zeige GPHb5 Antikörper) forms disulfide-linked homodimers without DMalpha

  8. findings suggest HLA-DM expression in antigen presenting cells controls class II-mediated type II collagen (zeige COL2A1 Antikörper)(261-273) peptide/epitope presentation & regulates CD4 (zeige CD4 Antikörper)+ T cell responses to this self epitope, potentially influencing CII-dependent autoimmunity

  9. Tumor cell expression of HLA-DMB is associated with increased numbers of tumor-infiltrating CD8 (zeige CD8A Antikörper) T lymphocytes and both are associated with improved survival in advanced-stage serous ovarian cancer.

  10. No individual component of conserved HLA-DM hydrogen bond network demonstrates an essential role in the DM catalytic mechanism. Catalytic potency of HLA-DM with each beta-chain mutant was equal to or greater than that observed with wild-type HLA-DR1 (zeige DR1 Antikörper).

HLA-DMB Antigen-Profil

Protein Überblick

HLA-DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II-associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail.

Genbezeichner und Symbole assoziert mit HLA-DMB

  • major histocompatibility complex, class II, DM beta (HLA-DMB) Antikörper
  • RT1 class II, locus DMb (RT1-DMb) Antikörper
  • major histocompatibility complex, class II, DM beta (PATR-DMB) Antikörper
  • D6S221E Antikörper
  • MHC-DMB Antikörper
  • RING7 Antikörper
  • RT1.DMb Antikörper
  • RT1.Mb Antikörper

Bezeichner auf Proteinebene für HLA-DMB

HLA class II histocompatibility antigen, DM beta chain , MHC class II HLA-DMB , MHC class II antigen DMB , MHC class II antigen HLA-DM beta chain , class II histocompatibility antigen, M beta chain , really interesting new gene 7 protein , MHC class II-like beta chain , RT1 class II, DM beta , major histocompatibility complex, class II, DM beta

GENE ID SPEZIES
3109 Homo sapiens
294273 Rattus norvegicus
449592 Pan troglodytes
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