anti-Maelstrom Spermatogenic Transposon Silencer (MAEL) Antikörper

Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Zusätzlich bieten wir Ihnen MAEL Proteine (6) und MAEL Kits (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MAEL 98558 Q8BVN9
MAEL 84944 Q96JY0
MAEL 364039  
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Top anti-MAEL Antikörper auf antikoerper-online.de

Showing 5 out of 5 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
357,50 €
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, WB Immunocytochemistry/Immunofluorescence: MAEL Antibody [NBP1-77139] - Immunofluorescence of Maelstrom in HeLa cells with Maelstrom antibody at 20 ug/mL. Western Blot: MAEL Antibody [NBP1-77139] - HeLa cell lysate with MAEL antibody at 1 ug/mL. 0.1 mg Anmelden zum Anzeigen 3 bis 6 Tage
341,00 €
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 11 bis 14 Tage
635,55 €
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Human Kaninchen Unkonjugiert IC, IF, ELISA, WB   100 μg Anmelden zum Anzeigen 15 bis 21 Tage
580,41 €
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Human Kaninchen Unkonjugiert ELISA, ICC, WB   100 μg Anmelden zum Anzeigen 7 bis 8 Tage
371,20 €
Details

MAEL Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Mouse (Murine)


Human


Rat (Rattus)


Weitere Antikörper gegen MAEL Interaktionspartner

Mouse (Murine) Maelstrom Spermatogenic Transposon Silencer (MAEL) Interaktionspartner

  1. MAEL HMG (zeige SSRP1 Antikörper)-box domain may contribute to MAEL function in selective processing of retrotransposon RNA into piRNAs.

  2. an important role for Mael in early oogenesis and during germ-cell differentiation from embryonic stem cells

  3. This study demonstrates that MAEL, a nuage component, is indispensable for the silencing of transposable elements (TEs (zeige TES Antikörper)) and identifies the initiation of meiosis as an important step in (TE) control in the male germline.

Human Maelstrom Spermatogenic Transposon Silencer (MAEL) Interaktionspartner

  1. Data suggest that overexpression of MAEL, caused by gene amplification and/or decreased miR (zeige MLXIP Antikörper)-186, has a critical oncogenic role in UCB pathogenesis by downregulation of MTSS1 (zeige MTSS1 Antikörper).

  2. Study demonstrated that MAEL interacts with Snail (zeige SNAI1 Antikörper) and inhibit E-cadherin (zeige CDH1 Antikörper) promoter activity. MAEL is an oncogene (zeige RAB1A Antikörper) that plays an important role in the development and progression of colon cancer.

  3. Immunofluorescence analysis showed that MAEL co-localizes with the stress granule marker PABPC1 (zeige PABPC1 Antikörper) in stress granules during oxidative stress. MAEL may be involved in miRNA-mediated gene silencing in SGs (zeige FBN1 Antikörper).

  4. Maelstrom promotes hepatocellular carcinoma metastasis by inducing epithelial-mesenchymal transition by way of Akt (zeige AKT1 Antikörper)/GSK-3beta (zeige GSK3b Antikörper)/Snail (zeige SNAI1 Antikörper) signaling.

  5. These results suggest that MAEL is a novel cancer/testis-associated gene and is regulated by DNA methylation (zeige HELLS Antikörper).

MAEL Antigen-Profil

Protein Überblick

Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for localization of germ-cell factors to the meiotic nuage (By similarity).

Genbezeichner und Symbole assoziert mit MAEL

  • maelstrom homolog (Drosophila) (Mael) Antikörper
  • maelstrom homolog (Drosophila) (MAEL) Antikörper
  • maelstrom spermatogenic transposon silencer (MAEL) Antikörper
  • maelstrom spermatogenic transposon silencer (Mael) Antikörper
  • protein maelstrom homolog (LOC100737640) Antikörper
  • 4933405K18Rik Antikörper
  • AU019877 Antikörper
  • CT128 Antikörper
  • RGD1309333 Antikörper
  • RP11-102C16.1 Antikörper
  • SPATA35 Antikörper

Bezeichner auf Proteinebene für MAEL

protein maelstrom homolog , cancer/testis antigen 128 , maelstrom homolog , spermatogenesis associated 35

GENE ID SPEZIES
98558 Mus musculus
541073 Bos taurus
100048945 Sus scrofa
84944 Homo sapiens
364039 Rattus norvegicus
100737640 Sus scrofa
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