anti-Maelstrom Spermatogenic Transposon Silencer (MAEL) Antikörper

Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Zusätzlich bieten wir Ihnen MAEL Proteine (6) und MAEL Kits (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MAEL 84944 Q96JY0
MAEL 98558 Q8BVN9
MAEL 364039  
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Top anti-MAEL Antikörper auf antikoerper-online.de

Showing 5 out of 5 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$411.13
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, WB Immunocytochemistry/Immunofluorescence: MAEL Antibody [NBP1-77139] - Immunofluorescence of Maelstrom in HeLa cells with Maelstrom antibody at 20 ug/mL. Western Blot: MAEL Antibody [NBP1-77139] - HeLa cell lysate with MAEL antibody at 1 ug/mL. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$485.88
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$537.17
Details
Human Kaninchen Unkonjugiert IC, IF, ELISA, WB   100 μg Anmelden zum Anzeigen 11 bis 16 Tage
$531.14
Details
Human Kaninchen Unkonjugiert ELISA, ICC, WB   100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$355.73
Details

MAEL Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität
Human


Mouse (Murine)


Rat (Rattus)


Weitere Antikörper gegen MAEL Interaktionspartner

Human Maelstrom Spermatogenic Transposon Silencer (MAEL) Interaktionspartner

  1. Data suggest that overexpression of MAEL, caused by gene amplification and/or decreased miR (zeige MLXIP Antikörper)-186, has a critical oncogenic role in UCB pathogenesis by downregulation of MTSS1 (zeige MTSS1 Antikörper).

  2. Study demonstrated that MAEL interacts with Snail (zeige SNAI1 Antikörper) and inhibit E-cadherin (zeige CDH1 Antikörper) promoter activity. MAEL is an oncogene (zeige RAB1A Antikörper) that plays an important role in the development and progression of colon cancer.

  3. Immunofluorescence analysis showed that MAEL co-localizes with the stress granule marker PABPC1 (zeige PABPC1 Antikörper) in stress granules during oxidative stress. MAEL may be involved in miRNA-mediated gene silencing in SGs (zeige FBN1 Antikörper).

  4. Maelstrom promotes hepatocellular carcinoma metastasis by inducing epithelial-mesenchymal transition by way of Akt (zeige AKT1 Antikörper)/GSK-3beta (zeige GSK3b Antikörper)/Snail (zeige SNAI1 Antikörper) signaling.

  5. These results suggest that MAEL is a novel cancer/testis-associated gene and is regulated by DNA methylation (zeige HELLS Antikörper).

Mouse (Murine) Maelstrom Spermatogenic Transposon Silencer (MAEL) Interaktionspartner

  1. MAEL HMG (zeige SSRP1 Antikörper)-box domain may contribute to MAEL function in selective processing of retrotransposon RNA into piRNAs.

  2. an important role for Mael in early oogenesis and during germ-cell differentiation from embryonic stem cells

  3. This study demonstrates that MAEL, a nuage component, is indispensable for the silencing of transposable elements (TEs (zeige TES Antikörper)) and identifies the initiation of meiosis as an important step in (TE) control in the male germline.

MAEL Antigen-Profil

Protein Überblick

Plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for localization of germ-cell factors to the meiotic nuage (By similarity).

Genbezeichner und Symbole assoziert mit MAEL

  • maelstrom spermatogenic transposon silencer (MAEL) Antikörper
  • maelstrom spermatogenic transposon silencer (Mael) Antikörper
  • 4933405K18Rik Antikörper
  • AU019877 Antikörper
  • CT128 Antikörper
  • RGD1309333 Antikörper
  • RP11-102C16.1 Antikörper
  • SPATA35 Antikörper

Bezeichner auf Proteinebene für MAEL

cancer/testis antigen 128 , maelstrom homolog , protein maelstrom homolog , spermatogenesis associated 35

GENE ID SPEZIES
84944 Homo sapiens
98558 Mus musculus
364039 Rattus norvegicus
541073 Bos taurus
100048945 Sus scrofa
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