anti-MYC Binding Protein 2 (MYCBP2) Antikörper

Probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins.

Alle Antikörper anzeigen Gen GeneID UniProt
MYCBP2 105689 Q7TPH6
MYCBP2 23077 O75592
MYCBP2    
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Showing 10 out of 16 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IF (p), IHC (p) Paraformaldehyde-fixed, paraffin embedded rat brain tissue, Antigen retrieval by boiling in sodium citrate buffer(pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with Rabbit Anti-MYCBP2 Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4°C, followed by a conjugated secondary and DAB staining Paraformaldehyde-fixed, paraffin embedded rat brain tissue, Antigen retrieval by boiling in sodium citrate buffer(pH6) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 30 minutes, Blocking buffer (normal goat serum) at 37°C for 20min, Antibody incubation with Rabbit Anti-MYCBP2 Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4°C, followed by a conjugated secondary and DAPI staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$295.90
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Human Kaninchen Unkonjugiert WB 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$486.94
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Human Kaninchen Alexa Fluor 594 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
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Human Kaninchen Alexa Fluor 488 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
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Human Kaninchen Alexa Fluor 555 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
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Human Kaninchen Alexa Fluor 647 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
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Human Kaninchen Cy3 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
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Human Kaninchen Cy5.5 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
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Human Kaninchen Cy7 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
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Human Kaninchen HRP IHC (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
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MYCBP2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine) ,


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Weitere Antikörper gegen MYCBP2 Interaktionspartner

Mouse (Murine) MYC Binding Protein 2 (MYCBP2) Interaktionspartner

  1. nuclear localization of Ran was strongly increased in MYCBP2-deficient DRGs

  2. Arf-bp1 and Pam (zeige PAM Antikörper) are novel regulators of circadian gene expression that target Rev-erb alpha (zeige NR1D1 Antikörper) for degradation

  3. Mycbp2 and Robo2 (zeige ROBO2 Antikörper) were found to cooperate within a genetic network that has profound effects on axon guidance

  4. Phr1 (zeige PLEKHB1 Antikörper) is identified as a key regulator of a core axon degeneration program that balances axon survival and loss in various neuronal cell types.

  5. The ubiquitin ligase (zeige RNF123 Antikörper) complex containing Pam (zeige PAM Antikörper)-Fbxo45 (zeige FBXO45 Antikörper) likely targets additional synaptic and axonal proteins, which may explain the overlapping neurodevelopmental defects observed in Phr1 (zeige PLEKHB1 Antikörper) and Fbxo45 (zeige FBXO45 Antikörper) deficiency.

  6. These results show that Phr1 (zeige PLEKHB1 Antikörper) is an essential regulator of retinal ganglion cell projection during both dLGN and SC topographic map development.

  7. p38 MAPK (zeige MAPK14 Antikörper) activation can inhibit activity-induced ion channel internalization and MYCBP2 regulates internalization of TRPV1 (zeige TRPV1 Antikörper) in peripheral sensory neurons as well as duration of thermal hyperalgesia through p38 MAPK (zeige MAPK14 Antikörper)

  8. Structures of both the first and second PHR domains of Mus (zeige TRPV6 Antikörper) musculus (mouse) Phr1 (MYC binding protein 2, Mycbp2) have been determined, revealing a novel beta sandwich fold composed of 11 antiparallel beta-strands.

  9. Phr1 (zeige PLEKHB1 Antikörper) is required for formation of major CNS axon tracts via a mechanism that is both cell-nonautonomous and independent of DLK (zeige DAPK3 Antikörper).

  10. Thus, efficacious pathfinding requires Phr1 (zeige PLEKHB1 Antikörper) activity for coordinating the cytoskeletal organization that distinguishes axons from growth cones.

Human MYC Binding Protein 2 (MYCBP2) Interaktionspartner

  1. Data indicate an oncogenic role for an Ikaros (zeige IKZF1 Antikörper) protein/MYCBP2 protein/proto-oncogene (zeige RAB1A Antikörper) protein c (zeige PROC Antikörper)-MYC (zeige MYC Antikörper) axis in adult acute lymphoblastic leukemia (ALL), providing a mechanism of target therapies that activate Ikaros (zeige IKZF1 Antikörper) in ALL.

  2. Arf-bp1 (zeige HUWE1 Antikörper) and Pam (zeige PAM Antikörper) are novel regulators of circadian gene expression that target Rev-erb alpha (zeige NR1D1 Antikörper) for degradation

  3. Data show that epithelial-mesenchymal transition (EMT (zeige ITK Antikörper))-transcription factors can be dynamically degraded by an atypical ubiquitin E3 ligase complex Skp1 (zeige SKP1 Antikörper)-Pam (zeige PAM Antikörper)-Fbxo45 (zeige FBXO45 Antikörper) (SPFFbxo45).

  4. In castration resistant prostate cancer, MYCBP2 is down-regulated at the mRNA and protein levels.

  5. We describe a distinct excavated optic disc anomaly associated with high myopia and increased axial length. The condition appears to follow an autosomal dominant pattern and segregate with a deletion in MYCBP2.

  6. Pam (zeige PAM Antikörper), through its interaction with tuberin (zeige TSC2 Antikörper), could regulate the ubiquitination and proteasomal degradation of the tuberin (zeige TSC2 Antikörper)-hamartin (zeige TSC1 Antikörper) complex particularly in the CNS

  7. PAM (zeige PAM Antikörper) the longest lasting nontranscriptional regulator of adenylyl cyclase activity known to date and presents a novel mechanism for the temporal regulation of cAMP signaling

  8. Identifies the region in PAM (zeige PAM Antikörper) that inhibits the domain of type V adenylyl cyclase.

  9. PAM (zeige PAM Antikörper) protein activated by facilitating the GDP/GTP (zeige AK3 Antikörper)-exchange of RHEBL1 (zeige RHEBL1 Antikörper) protein which is an activator of mTOR (zeige FRAP1 Antikörper) protein.

MYCBP2 Antigen-Profil

Protein Überblick

Probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. May function as a facilitator or regulator of transcriptional activation by MYC. May have a role during synaptogenesis.

Genbezeichner und Symbole assoziert mit MYCBP2

  • MYC binding protein 2 (Mycbp2) Antikörper
  • MYC binding protein 2, E3 ubiquitin protein ligase (MYCBP2) Antikörper
  • AU023734 Antikörper
  • AW107953 Antikörper
  • AW546647 Antikörper
  • C130061D10Rik Antikörper
  • PAM Antikörper
  • Phr1 Antikörper
  • R75243 Antikörper

Bezeichner auf Proteinebene für MYCBP2

Myc-binding protein 2 , pam, highwire, rpm 1 , pam/highwire/rpm-1 protein , probable E3 ubiquitin-protein ligase MYCBP2 , protein associated with Myc , myc-binding protein 2

GENE ID SPEZIES
105689 Mus musculus
23077 Homo sapiens
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