MAD2L1 Binding Protein (MAD2L1BP) ELISA Kits

The protein encoded by MAD2L1BP was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). Zusätzlich bieten wir Ihnen MAD2L1BP Antikörper (67) und MAD2L1BP Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Ratte MAD2L1BP MAD2L1BP 316237  
Anti-Human MAD2L1BP MAD2L1BP 9587 Q15013
Anti-Maus MAD2L1BP MAD2L1BP 66591 Q9DCX1
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Weitere ELISA Kits für MAD2L1BP Interaktionspartner

Human MAD2L1 Binding Protein (MAD2L1BP) Interaktionspartner

  1. Thes authors show that p31 (zeige ATP6V1E1 ELISA Kits)(comet) binding to the TRIP13 (zeige TRIP13 ELISA Kits) N-terminal domain positions the disordered MAD2 (zeige MAD2L1 ELISA Kits) N-terminus for engagement by the TRIP13 (zeige TRIP13 ELISA Kits) "pore loops", which then unfold MAD2 (zeige MAD2L1 ELISA Kits) in the presence of ATP.

  2. p31comet-induced cell death is mediated by interactions with Mad2 (zeige MAD2L1 ELISA Kits)

  3. the oligomeric form of TRIP13 binds both p31(comet) and MCC

  4. joint action of TRIP13 (zeige TRIP13 ELISA Kits) and p31 (zeige ATP6V1E1 ELISA Kits)(comet) also promotes the release of Mad2 (zeige MAD2L1 ELISA Kits) from MCC, participates in the complete disassembly of MCC and abrogates checkpoint inhibition of APC (zeige APC ELISA Kits)/C

  5. Altered p31 (zeige ATP6V1E1 ELISA Kits)(Comet):Mad2 (zeige MAD2L1 ELISA Kits) expression ratios may provide new insight into altered spindle assembly checkpoint function and the generation of chromosomal instability in tumors.

  6. attenuating the affinity of p31 (zeige ATP6V1E1 ELISA Kits)(Comet) for Mad2 (zeige MAD2L1 ELISA Kits) by phosphorylation promotes SAC (zeige ADCY10 ELISA Kits) activity in mitosis. Specifically, phosphorylation of Ser (zeige SIGLEC1 ELISA Kits)-102 weakens p31 (zeige ATP6V1E1 ELISA Kits)(Comet)-Mad2 (zeige MAD2L1 ELISA Kits) binding and enhances p31 (zeige ATP6V1E1 ELISA Kits)(Comet)-mediated bypass of the SAC (zeige ADCY10 ELISA Kits).

  7. study found p31 (zeige ATP6V1E1 ELISA Kits)(comet) traffics on and off kinetochores and also present in the cytosol; Cells depleted of p31 (zeige ATP6V1E1 ELISA Kits)(comet) arrest in metaphase with mature bipolar kinetochore-microtubule attachments; propose that p31 (zeige ATP6V1E1 ELISA Kits)(comet) is an essential component of machinery that silences the checkpoint during each cell cycle

  8. the importance of p31 (zeige ATP6V1E1 ELISA Kits)(comet) in checkpoint silencing and its potential as a target for antimitotic therapies.

  9. The binding of p31 (zeige ATP6V1E1 ELISA Kits)(comet) to Mad2 (zeige MAD2L1 ELISA Kits) in mitotic checkpoint (zeige BUB3 ELISA Kits) complex may trigger a conformational change in Cdc20 (zeige CDC20 ELISA Kits) that facilitates its phosphorylation by Cdk (zeige CDK4 ELISA Kits), and that the latter process may promote its dissociation from BubR1 (zeige BUB1B ELISA Kits).

  10. both p31 (zeige ATP6V1E1 ELISA Kits)(comet) and ubiquitination of Cdc20 (zeige CDC20 ELISA Kits) are critical mechanisms of checkpoint inactivation. They act redundantly to promote Mad2 (zeige MAD2L1 ELISA Kits) dissociation from Cdc20 (zeige CDC20 ELISA Kits)

Mouse (Murine) MAD2L1 Binding Protein (MAD2L1BP) Interaktionspartner

  1. p31comet-induced cell death is mediated by interactions with Mad2 (zeige MXI1 ELISA Kits)

MAD2L1BP Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1 (MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Genbezeichner und Symbole assoziert mit MAD2L1BP

  • MAD2L1 binding protein (Mad2l1bp) Antikörper
  • MAD2L1 binding protein (MAD2L1BP) Antikörper
  • 0610009D16Rik Antikörper
  • 2510031P20Rik Antikörper
  • AU018945 Antikörper
  • AW550977 Antikörper
  • C76045 Antikörper
  • CMT2 Antikörper
  • CMT2A Antikörper
  • CMT2B Antikörper
  • MAD2L1BP Antikörper
  • Mad2lbp Antikörper
  • mKIAA0110 Antikörper
  • RP1-261G23.6 Antikörper

Bezeichner auf Proteinebene für MAD2L1BP

MAD2L1-binding protein , MAD2L1 binding protein , caught by MAD2 protein

316237 Rattus norvegicus
421448 Gallus gallus
462721 Pan troglodytes
474916 Canis lupus familiaris
615542 Bos taurus
701099 Macaca mulatta
9587 Homo sapiens
66591 Mus musculus
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