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MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1) ELISA Kits

MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Zusätzlich bieten wir Ihnen MAD2L1 Antikörper (118) und MAD2L1 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Maus MAD2L1 MAD2L1 56150 Q9Z1B5
Anti-Human MAD2L1 MAD2L1 4085 Q13257
Anti-Ratte MAD2L1 MAD2L1 297176  
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Weitere ELISA Kits für MAD2L1 Interaktionspartner

Mouse (Murine) MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1) Interaktionspartner

  1. p31comet-induced cell death is mediated by interactions with Mad2 (zeige MXI1 ELISA Kits)

  2. study shows that Mad2 (zeige MXI1 ELISA Kits) is a novel substrate for CCP6 (zeige AGBL4 ELISA Kits) in megakaryocytes; Mad2 (zeige MXI1 ELISA Kits) polyglutamylation plays a crucial role in the regulation of megakaryopoiesis

  3. Exacerbating chromosome missegregation in CENP-E (zeige CENPE ELISA Kits)+/- mice by reducing levels of another mitotic checkpoint component (zeige BUB3 ELISA Kits), Mad2 (zeige MXI1 ELISA Kits), results in elevated cell death and decreased tumor formation compared with reduction of either protein alone.

  4. Mad2 (zeige MXI1 ELISA Kits) is also repressed by p53 (zeige TP53 ELISA Kits) and its upregulation is required for chromosome instability in a p53 (zeige TP53 ELISA Kits) mutant tumor model

  5. Data show that Mad2 (zeige MXI1 ELISA Kits) haploinsufficiency is protective in the presence of a cycle-specific DNA synthesis agent in vivo, and Ape1/Ref-1 (zeige APEX1 ELISA Kits) inhibitor in vitro.

  6. Pcid2 (zeige PCID2 ELISA Kits) is essential for B cell survival through the regulation of MAD2 (zeige MXI1 ELISA Kits) expression during B cell differentiation

  7. tumours that experience transient Mad2 (zeige MXI1 ELISA Kits) overexpression and consequent chromosome instability recur at markedly elevated rates

  8. a functional Mad2 (zeige MXI1 ELISA Kits)-dependent spindle checkpoint exists during the first meiotic division in mammalian oocytes

  9. Data show that the loss of Trrap (zeige TRRAP ELISA Kits) leads to chromosome missegregation, mitotic exit failure and compromised mitotic checkpoints, which are caused by defective Trrap (zeige TRRAP ELISA Kits)-mediated transcription of the mitotic checkpoint (zeige BUB3 ELISA Kits) proteins Mad1 (zeige MXD1 ELISA Kits) and Mad2 (zeige MXI1 ELISA Kits).

  10. that Brca1 (zeige BRCA1 ELISA Kits)(Delta11/Delta11) cells displayed decreased expression of a number of genes that are involved in the spindle checkpoint, including Mad2 (zeige MXI1 ELISA Kits)

Human MAD2 Mitotic Arrest Deficient-Like 1 (Yeast) (MAD2L1) Interaktionspartner

  1. in addition to its role in checkpoint signaling, MAD2 ensures chromosome stability through the regulation of AURORA B (zeige AURKB ELISA Kits).

  2. Aberrant Mad2 expression was associated with cell proliferation and genetic instability, which may contribute to the carcinogenesis of PGI (zeige BGN ELISA Kits)-DLBCL. Mad2 overexpression indicated a poor DFS (zeige FST ELISA Kits).

  3. interactions between Mad2 and H3K4 regulate resolution of the spindle assembly checkpoint by limiting closed Mad2 availability for Cdc20 (zeige CDC20 ELISA Kits) inhibition.

  4. we showed that BubR1 (zeige BUB1B ELISA Kits) and Mad2 are overexpressed in oral squamous cell carcinoma cell lines and linked such overexpression to attenuated spindle assembly checkpoint activity.

  5. Studied the folding/unfolding process of the open and closed conformers of human Mad2.

  6. MAD1L1 (zeige MAD1L1 ELISA Kits) Arg558His and MAD2L1 Leu84Met interaction with smoking increase the risk of colorectal cancer

  7. p31comet-induced cell death is mediated by interactions with Mad2

  8. MAD2L1 and BUB1 (zeige BUB1 ELISA Kits) may play important roles in breast cancer progression, and measuring the expression of these genes may assist the prediction of breast cancer prognosis.

  9. We also show that replication perturbations result in relocalization of MAD1 (zeige MXD1 ELISA Kits)/MAD2 in human cells, suggesting that the role of SAC (zeige ADCY10 ELISA Kits) in DNA repair is conserved.

  10. Data indicate the structure of the intermediate conformer of the multistate checkpoint protein mitotic arrest deficient 2 (Mad2) protein.

MAD2L1 Antigen-Profil

Beschreibung des Gens

MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has been mapped to chromosome 14.

Genbezeichner und Symbole assoziert mit MAD2L1

  • MAD2 mitotic arrest deficient-like 1 (yeast) (MAD2L1) Antikörper
  • MAD2 mitotic arrest deficient-like 1 (yeast) (mad2l1) Antikörper
  • MAD2 mitotic arrest deficient-like 1 (mad2l1) Antikörper
  • MAD2 mitotic arrest deficient-like 1 (MAD2L1) Antikörper
  • MAD2 mitotic arrest deficient-like 1 (yeast) (LOC100218172) Antikörper
  • MAD2 mitotic arrest deficient-like 1 (Mad2l1) Antikörper
  • MAD2 mitotic arrest deficient-like 1 (yeast) (Mad2l1) Antikörper
  • AA673185 Antikörper
  • cb408 Antikörper
  • HSMAD2 Antikörper
  • MAD2 Antikörper
  • MAD2L1 Antikörper
  • XMad2 Antikörper
  • zgc:112133 Antikörper

Bezeichner auf Proteinebene für MAD2L1

MAD2-like 1 , mitotic spindle assembly checkpoint protein MAD2A , spindle assembly checkpoint protein Mad2 , MAD2 mitotic arrest deficient-like 1 (yeast) , MAD2 mitotic arrest deficient-like 1 , MAD2 (mitotic arrest deficient, homolog)-like 1 , MAD2-like protein 1 , mitotic arrest deficient 2-like protein 1 , MAD2 (mitotic arrest deficient, yeast, homolog)-like 1 , mitotic arrest deficient, yeast, homolog-like 1

GENE ID SPEZIES
461661 Pan troglodytes
550434 Danio rerio
708574 Macaca mulatta
787996 Bos taurus
100125170 Xenopus (Silurana) tropicalis
100137358 Papio anubis
100218172 Taeniopygia guttata
56150 Mus musculus
380433 Xenopus laevis
4085 Homo sapiens
422675 Gallus gallus
476070 Canis lupus familiaris
337870 Bos taurus
297176 Rattus norvegicus
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