Lysyl Oxidase-Like 1 Proteine (LOXL1)

LOXL1 encodes a member of the lysyl oxidase gene family. Zusätzlich bieten wir Ihnen LOXL1 Antikörper (75) und LOXL1 Kits (17) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
LOXL1 4016 Q08397
LOXL1 16949 P97873
LOXL1 315714  
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Top LOXL1 Proteine auf antikoerper-online.de

Showing 10 out of 15 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$8,498.50
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$8,498.50
Details
Escherichia coli (E. coli) Ratte His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$765.00
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Escherichia coli (E. coli) Maus His tag   50 μg Anmelden zum Anzeigen 11 Days
$341.00
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Escherichia coli (E. coli) Human His tag   50 μg Anmelden zum Anzeigen 11 Days
$341.00
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Hefe Maus His tag   50 μg Anmelden zum Anzeigen 8 bis 11 Tage
$341.00
Details
Escherichia coli (E. coli) Maus His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$733.00
Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$672.00
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,417.33
Details
Escherichia coli (E. coli) Human Unkonjugiert   5 applications Anmelden zum Anzeigen 1 bis 2 Tage
$312.71
Details

LOXL1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,

Mouse (Murine) , ,
,
Rat (Rattus)

Weitere Proteine zu Lysyl Oxidase-Like 1 (LOXL1) Interaktionspartnern

Rhesus Monkey Lysyl Oxidase-Like 1 (LOXL1) Interaktionspartner

  1. high lysyl oxidase (zeige LOX Proteine) activity is associated with ischemic hearts.

Human Lysyl Oxidase-Like 1 (LOXL1) Interaktionspartner

  1. These findings provide evidence for a functional role of alternative splicing coupled to NMD in the posttranscriptional regulation of LOXL1 gene expression and suggest this mechanism to represent a dynamic mode of adapting LOXL1 expression to PEX (zeige PHEX Proteine)-associated environmental and nutritional cues.

  2. remenopausal and postmenopausal women with Pelvic Organ Prolapse (POP (zeige PREP Proteine)) exhibit differential expression of LOXL1 suggesting different pathways in the pathogenesis of POP (zeige PREP Proteine). The role of biopsy location on LOXL1 expression requires further investigation.

  3. In this study, we found no significant association between allele and genotype frequencies of APOE (zeige APOE Proteine); the intronic SNP rs2165241 and the non-synonymous SNP rs3825942 in exon 1 of LOXL1 are significantly associated with pseudoexfoliation syndrome and exfoliation glaucoma in the Turkish population.

  4. The LOXL1 SNPs, rs1048661 and rs3825942, are associated with PXF (zeige PEX19 Proteine) in the South Indian population correlating with lowered LOX (zeige LOX Proteine) activity in the aqueous humor. The increased level of total TGF-beta (zeige TGFB1 Proteine) in the aqueous humor of PXF (zeige PEX19 Proteine) cases is possibly associated with LOX (zeige LOX Proteine) regulation which needs further investigation.

  5. A rare protective allele at LOXL1,Tyr407Phe, was identified. It is found exclusively in the Japanese population. It confers 25-fold resistance to XFS (zeige FST Proteine). It segregated with the common rs3825942[A] (p.Asp153) in all but 2 patients examined. In spheroids, this haplotype conferred a significant increase in the strength of cellular adhesion in comparison to 3 haplotypes with the wild-type allele.

  6. Findings of this current study indicate a different LOXL1 gene expression pattern compared with a recent study that was also performed in the Turkish population.

  7. LOXL1 transcriptional activity was dramatically reduced when a recombinant DNMT3A (zeige DNMT3A Proteine) was concomitantly overexpressed.

  8. The present study, for the first time, shows that the pseudoexfoliation syndrome-associated variant residues in LOXL1 influence processing of the protein, most likely by BMP-1 (zeige BMP1 Proteine).

  9. In this study group of Turkish population, no LOXL1 mutations were found. No associations between the defined SNPs (A320A, R141L and F184F) and the severity of the disease were detected.

  10. Here we show that orthotopic implantation of rat prostate AT-1 tumour cells increased LOX (zeige LOX Proteine) and LOXLs mRNA expressions in the tumour and in the surrounding non-malignant prostate tissue

Cow (Bovine) Lysyl Oxidase-Like 1 (LOXL1) Interaktionspartner

Mouse (Murine) Lysyl Oxidase-Like 1 (LOXL1) Interaktionspartner

  1. LOXL1-/- mutant mice develop appendicular and axial skeletal phenotypes characterized by decreased bone volume fraction and compromised trabecular microstructure, predominantly in females

  2. Elimination of LOXL1 in mice impairs the blood-aqueous humor barrier in the ocular anterior segment and causes lens abnormalities consistent with cataract formation, but does not result in deposition of macromolecular material or glaucoma.

  3. There is a possible fundamental role of LOXL-1 in cardiac hypertrophy.

  4. loxl appears non-allelic to rough coat in mice; heart- and skin-specific downregulation of LOXL in rough coat mice, however, may contribute to the extracellular matrix alterations and the rough coat phenotype

  5. Data report that cells in the hippocampal granule cell layer of LOXL -/- mice have significantly smaller somas and muted (zeige MUTED Proteine) long-term potentiation compared to LOXL +/+ mice.

  6. pro-regions of lysyl oxidase (zeige LOX Proteine) and lysyl oxidase-like 1 are required for deposition onto elastic fibers

  7. LOXL1 deficiency caused failure of elastic fiber homeostasis leading to pelvic floor disorders

  8. LOXL1 (lysyl oxidase-like 1) mutation results in a global defect in connective tissues and correlates with altered biomechanical behavior of the vagina and supportive tissues

  9. LOXL1-KO lower urogenital tract anatomical and functional phenotype resembles female pelvic floor dysfunction in humans. Elastin (zeige ELN Proteine) disorganization may lead to such functional abnormalities.

  10. Loxl1(-/-) males bred with control females demonstrated relative fecundity values intermediate between Loxl1(-/-) pairs (lowest fecundity) and control pairs (highest fecundity), suggesting a component of male-factor infertility.

LOXL1 Protein Überblick

Protein Überblick

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.

Genbezeichner und Symbole assoziert mit Lysyl Oxidase-Like 1 Proteine (LOXL1)

  • lysyl oxidase like 1 (LOXL1)
  • lysyl oxidase like 1 (loxl1)
  • lysyl oxidase-like 1 (Loxl1)
  • lysyl oxidase-like 1 (loxl1)
  • lysyl oxidase like 1 L homeolog (loxl1.L)
  • lol Protein
  • loxl Protein
  • loxl-1 Protein
  • oxl-1 Protein
  • si:ch211-238c15.1 Protein

Bezeichner auf Proteinebene für Lysyl Oxidase-Like 1 Proteine (LOXL1)

lysyl oxidase-like 1 , lysyl oxidase homolog 1-like , lysyl oxidase homolog 1 , lysyl oxidase-like protein 1 , lysyl oxidase 2

GENE ID SPEZIES
426411 Gallus gallus
706464 Macaca mulatta
100051862 Equus caballus
100124878 Xenopus (Silurana) tropicalis
100388123 Callithrix jacchus
100606325 Nomascus leucogenys
4016 Homo sapiens
281903 Bos taurus
16949 Mus musculus
315714 Rattus norvegicus
560115 Danio rerio
496210 Xenopus laevis
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