anti-Lysyl Oxidase (LOX) Antikörper

The protein encoded by LOX is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. Zusätzlich bieten wir Ihnen LOX Kits (45) und LOX Proteine (13) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
LOX 4015 P28300
LOX 16948 P28301
LOX 24914 P16636
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Top anti-LOX Antikörper auf antikoerper-online.de

Showing 10 out of 194 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert FACS, ICC, IF, IP, SimWes, WB Flow Cytometry: LOX propeptide Antibody [NBP1-30327] - Staining of NTERA-2 cells using NP1-30327 at a 1:200 dilution detected using Dylight-488 conjugated goat anti-rabbit IgG secondary antibody. Immunocytochemistry/Immunofluorescence: LOX propeptide Antibody [NBP1-30327] - Staining in Hela cells detected with a Dylight 488 labeled secondary antibody (Green) with Hoechst 33258 nuclear counterstain (Blue). 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$381.94
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), IHC, WB Staining of LOPP in mouse intestine using ABIN258371. Western Blot: LOX propeptide Antibody [ABIN2583718] - Detection of LOPP in MC3T3-E1 cell lysate. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$408.19
Details
Rind (Kuh) Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), SimWes, WB Immunohistochemistry: LOX Antibody [ABIN250966] - Human placental villi, 40X. Staining of placental trophoblasts using ABIN250966 at 10 ug/ml. Detection of LOX in mouse kidney lysate using ABIN250966 (1:1,000). ECL detection was 15 sec. 0.05 mL Anmelden zum Anzeigen 7 bis 9 Tage
$408.19
Details
Human Kaninchen Unkonjugiert ICC, IHC (fro), IF, IHC (p), IHC, WB Staining of LOX in mouse spleen using ABIN258622. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$408.19
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, SimWes, WB Simple Western: LOX propeptide Antibody [NBP1-30012] - Simple Western lane view shows a specific band for LOX propeptide in 0.05 mg/ml of Jurkat lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system. Western Blot: LOX propeptide Antibody [NBP1-30012] - Western blot on cytoplasmic (c) and nuclear (n) extracts of NIH 3T3, ras-transformed (RS 485), PMEF and TGM-1 mouse fibroblast cells. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$381.94
Details
Human Kaninchen Unkonjugiert EIA, FACS, WB Flow cytometric analysis of 293 cells using  Lysyl oxidase Antibody (Center) Cat.-No AP52513PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Western blot analysis of  Lysyl oxidase Antibody (Center) in MDA-MB468 cell line lysates (35ug/lane). LOX (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Maus Unkonjugiert WB LOX Antibody (Center)(Ascites) (ABIN1882261) western blot analysis in Jurkat cell line lysates (35 µg/lane). This demonstrates the LOX antibody detected the LOX protein (arrow). 0.1 mL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Maus Unkonjugiert WB LOX Antibody (Center) (ABIN1882262) western blot analysis in MDA-MB231 cell line lysates (35 µg/lane). This demonstrates the LOX antibody detected the LOX protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert ICC, IF, WB Western Blot: LOX Antibody [ABIN4331347] - Analysis of LOX in human kidney Immunocytochemistry/Immunofluorescence: LOX Antibody [ABIN4331347] - LOX antibody was tested in HeLa cells with Dylight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 (red). 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$408.19
Details

LOX Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-LOX Antikörper

  1. Human Polyclonal LOX Primary Antibody für ICC, IF - ABIN4331341 : Ovchinnikova, Robertson, Wågsäter, Folco, Hyry, Myllyharju, Eriksson, Libby, Hansson: T-cell activation leads to reduced collagen maturation in atherosclerotic plaques of Apoe(-/-) mice. in The American journal of pathology 2009 (PubMed)
    Show all 17 Pubmed References

  2. Cow (Bovine) Polyclonal LOX Primary Antibody für ICC, IF - ABIN4331351 : Atsawasuwan, Mochida, Katafuchi, Kaku, Fong, Csiszar, Yamauchi: Lysyl oxidase binds transforming growth factor-beta and regulates its signaling via amine oxidase activity. in The Journal of biological chemistry 2008 (PubMed)
    Show all 14 Pubmed References

  3. Cow (Bovine) Polyclonal LOX Primary Antibody für ICC, IF - ABIN250966 : Wilhelmus, Bol, van Duinen, Drukarch: Extracellular matrix modulator lysyl oxidase colocalizes with amyloid-beta pathology in Alzheimer's disease and hereditary cerebral hemorrhage with amyloidosis--Dutch type. in Experimental gerontology 2013 (PubMed)
    Show all 10 Pubmed References

  4. Human Polyclonal LOX Primary Antibody für ICC, IHC (fro) - ABIN258622 : Jeay, Pianetti, Kagan, Sonenshein: Lysyl oxidase inhibits ras-mediated transformation by preventing activation of NF-kappa B. in Molecular and cellular biology 2003 (PubMed)
    Show all 8 Pubmed References

  5. Human Polyclonal LOX Primary Antibody für ICC, IF - ABIN258371 : Palamakumbura, Jeay, Guo, Pischon, Sommer, Sonenshein, Trackman: The propeptide domain of lysyl oxidase induces phenotypic reversion of ras-transformed cells. in The Journal of biological chemistry 2004 (PubMed)
    Show all 5 Pubmed References

  6. Human Polyclonal LOX Primary Antibody für FACS, ICC - ABIN447477 : Sato, Trackman, Mäki, Myllyharju, Kirsch, Sonenshein: The Ras signaling inhibitor LOX-PP interacts with Hsp70 and c-Raf to reduce Erk activation and transformed phenotype of breast cancer cells. in Molecular and cellular biology 2011 (PubMed)
    Show all 4 Pubmed References

  7. Human Monoclonal LOX Primary Antibody für WB - ABIN1882261 : Gao, Xiao, Ma, Li, Liu, Feng, Fang, Wu, Han, Zhang, Sun, Wu, Padera, Chen, Wong, Ge, Ji: LKB1 inhibits lung cancer progression through lysyl oxidase and extracellular matrix remodeling. in Proceedings of the National Academy of Sciences of the United States of America 2010 (PubMed)
    Show all 3 Pubmed References

  8. Human Monoclonal LOX Primary Antibody für WB - ABIN1882262 : Santhanam, Baker, Hegamyer, Kirschmann, Colburn: Pdcd4 repression of lysyl oxidase inhibits hypoxia-induced breast cancer cell invasion. in Oncogene 2010 (PubMed)
    Show all 3 Pubmed References

  9. Human Polyclonal LOX Primary Antibody für ICC, IF - ABIN440592 : Di Stefano, Torsello, Bianchi, Cifola, Mangano, Bovo, Cassina, De Marco, Corti, Meregalli, Bombelli, Viganò, Battaglia, Strada, Perego: Major Action of Endogenous Lysyl Oxidase in Clear Cell Renal Cell Carcinoma Progression and Collagen Stiffness Revealed by Primary Cell Cultures. in The American journal of pathology 2016 (PubMed)
    Show all 2 Pubmed References

  10. Human Polyclonal LOX Primary Antibody für ICC, IF - ABIN4331347 : Contente, Yeh, Friedman: Tumor suppressive effect of lysyl oxidase proenzyme. in Biochimica et biophysica acta 2009 (PubMed)

Weitere Antikörper gegen LOX Interaktionspartner

Zebrafish Lysyl Oxidase (LOX) Interaktionspartner

  1. Partial knockdown of lysyl oxidase genes sensitizes the developing embryo to dithiocarbamate exposure.

  2. Data reveal a role for lysyl oxidase in early morphogenesis, especially in muscle development and neurogenesis, and resume some aspects of physiopathology of copper metabolism.

Human Lysyl Oxidase (LOX) Interaktionspartner

  1. Results show that CTGF (zeige CTGF Antikörper) mediates the GDF8 (zeige MSTN Antikörper)-induced up-regulation of LOX expression and increases in LOX activity in human granulosa cells.

  2. The LOXL1 (zeige LOXL1 Antikörper) SNPs, rs1048661 and rs3825942, are associated with PXF (zeige PEX19 Antikörper) in the South Indian population correlating with lowered LOX activity in the aqueous humor. The increased level of total TGF-beta (zeige TGFB1 Antikörper) in the aqueous humor of PXF (zeige PEX19 Antikörper) cases is possibly associated with LOX regulation which needs further investigation.

  3. These findings suggest that LOX induces an age-dependent disturbance of diastolic function and aggravates Ang II (zeige AGT Antikörper)-induced hypertrophy, which provides novel insights into the role of LOX in cardiac performance.

  4. LOX, a hypoxia-responsive gene that encodes lysyl oxidase, is activated by HIF-2-alpha (zeige EPAS1 Antikörper) more than HIF-1 (zeige HIF1A Antikörper). Two new hypoxia response elements identified in the LOX promoter mediate most HIF responsiveness.

  5. our findings show that LOX supports colorectal cancer cell dissemination in the bone marrow

  6. LOX G473A polymorphism apparently elevated human sensitivity to cigarette smoking carcinogens for eliciting cancers in the lung and colon only. Thus, LOX G473A polymorphism positively correlates with carcinogenesis and it may be used as an ideal intrinsic biomarker for prediction or diagnosis of carcinogenesis in humans.

  7. increased cortisol and 11beta-HSD1 (zeige HSD11B1 Antikörper) abundance and decreased LOX abundance were observed in human amnion tissue after the labor-initiated spontaneous rupture of membranes

  8. endogenous LOX is overexpressed in clear cell renal cell carcinoma (zeige MOK Antikörper), is involved in a positive-regulative loop with HIF-1alpha (zeige HIF1A Antikörper), and has a major action on clear cell renal cell carcinoma (zeige MOK Antikörper) progression through cellular adhesion, migration, and collagen matrix stiffness increment

  9. colorectal carcinoma perilesional extracellular matrix has increased content of lysyl oxidase

  10. LOX affects the epithelial-mesenchymal transition of gastric cancer cells in hypoxic conditions.

Pig (Porcine) Lysyl Oxidase (LOX) Interaktionspartner

  1. Statins normalize vascular lysyl oxidase (LOX) down-regulation induced by proatherogenic risk factors.

Cow (Bovine) Lysyl Oxidase (LOX) Interaktionspartner

  1. These results indicate that proLOX could be processed by two different mechanisms producing two forms of active LOX.

  2. Lysyl oxidase enhances elastin (zeige ELN Antikörper) synthesis and matrix formation by vascular smooth muscle cells

  3. Lysyl oxidase has a role in oxidizing basic fibroblast growth factor (zeige FGF2 Antikörper) and inactivating its mitogenic potential

  4. In cases of vascular calcification, the decreased expression of LOX may be partially responsible for decreased vascular elasticity and also for the decreased formation of new elastic fibers.

  5. Statins normalize vascular lysyl oxidase down-regulation induced by proatherogenic risk factors.

Mouse (Murine) Lysyl Oxidase (LOX) Interaktionspartner

  1. Data show that LOX-PP enhances adipogenesis at least partially through inhibition of FGF-2 (zeige FGF2 Antikörper) receptor signaling.

  2. LOX targeting reduces peritoneal fibrosis.

  3. Absence of lysyl oxidase (Lox) causes thoracic aortic aneurysms. The aortic mechanical behavior of Lox(-/-) mice is consistent with reduced elastin (zeige ELN Antikörper) and collagen cross-linking but demonstrates vascular location-specific differences. Lox(-/-) aortas show upregulation of matrix remodeling genes and location-specific differential expression of other matrix and smooth muscle cell gene sets.

  4. Findings from this study indicate that preventing LOX overexpression may be protective against high glucose-induced apoptosis in retinal vascular cells associated with diabetic retinopathy.

  5. LOX family members contribute significantly to the detrimental effects of cardiac remodelling, highlighting LOX inhibition as a potential therapeutic strategy for post-infarction recovery

  6. Findings suggest that the lysyl oxidase (LOX)-mediated organization of collagen fibers in the extracellular matrix is an important regulator of osteoblastogenesis.

  7. The data suggest a fibromodulin (zeige FMOD Antikörper)-modulated collagen cross-linking mechanism where fibromodulin (zeige FMOD Antikörper) binds to a specific part of the collagen domain and also forms a complex with lysyl oxidase, targeting the enzyme toward specific cross-linking sites.

  8. Data suggest of pharmacologic targeting of lysyl oxidase (LOX) pathway to inhibit liver fibrosis and promote its resolution.

  9. Cu chaperone function of Atox1 (zeige ATOX1 Antikörper) mediated through Cu transporter ATP7A (zeige ATP7A Antikörper) is required for VEGF (zeige VEGFA Antikörper)-induced angiogenesis via activation of Cu enzyme lysyl oxidase.

  10. CTR1 (zeige SLC31A1 Antikörper), ATP7A (zeige ATP7A Antikörper), and lysyl oxidase were upregulated in the lung tissues and pulmonary arteries of mice with hypoxia-induced pulmonary hypertension and pulmonary arterial smooth muscle cells.

LOX Antigen-Profil

Protein Überblick

The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit anti-Lysyl Oxidase (LOX) Antikörper

  • lysyl oxidase (LOX) Antikörper
  • lysyl oxidase (lox) Antikörper
  • lysyl oxidase a (loxa) Antikörper
  • lysyl oxidase L homeolog (lox.L) Antikörper
  • lysyl oxidase (Lox) Antikörper
  • AI893619 Antikörper
  • H-rev142 Antikörper
  • lox Antikörper
  • MGC146507 Antikörper
  • Rrg1 Antikörper
  • TSC-160 Antikörper
  • Xlox Antikörper
  • zgc:77447 Antikörper

Bezeichner auf Proteinebene für anti-Lysyl Oxidase (LOX) Antikörper

lysyl oxidase , protein-lysine 6-oxidase-like , protein-lysine 6-oxidase , ras excision protein , ras recision gene (rrg) , Lysyl oxidase (an H-rev gene with its expression down-regulated in HRAS-transformed rat 208F fibroblasts)

GENE ID SPEZIES
471614 Pan troglodytes
699997 Macaca mulatta
780067 Xenopus (Silurana) tropicalis
100189621 Oncorhynchus mykiss
100457685 Pongo abelii
404621 Danio rerio
734204 Xenopus laevis
4015 Homo sapiens
100525278 Sus scrofa
280841 Bos taurus
16948 Mus musculus
24914 Rattus norvegicus
396474 Gallus gallus
481478 Canis lupus familiaris
100720740 Cavia porcellus
100357045 Oryctolagus cuniculus
101112220 Ovis aries
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