anti-Lon Peptidase 1, Mitochondrial (LONP1) Antikörper

LONP1 encodes a mitochondrial matrix protein in the Lon family of ATP-dependent proteases. Zusätzlich bieten wir Ihnen Lon Peptidase 1, Mitochondrial Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
LONP1 9361 P36776
LONP1 74142 Q8CGK3
LONP1 170916 Q924S5
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Top anti-Lon Peptidase 1, Mitochondrial Antikörper auf antikoerper-online.de

Showing 10 out of 73 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB LONP1 Antibody (Center) (ABIN1881504) western blot analysis in Hela cell line lysates (35 µg/lane). This demonstrates the LONP1 antibody detected the LONP1 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), SimWes, WB Western Blot: LONP1 Antibody [NBP1-81734] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells). Lane 3: PC12 cell lysate (Pheochromocytoma of rat adrenal medulla). Immunofluorescence: LONP1 Antibody [NBP1-81734] - Staining of human cell line U-251 MG shows positivity in mitochondria. Antibody staining is shown in green. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human cervical carcinoma labeled with Anti- LONP1 Polyclonal Antibody, Unconjugated (ABIN705806) at 1:200 followed by conjugation to the secondary antibody Formalin-fixed and paraffin embedded rat colon labeled with Anti- LONP1 Polyclonal Antibody, Unconjugated (ABIN705806) at 1:200 followed by conjugation to the secondary antibody Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$295.90
Details
Human Kaninchen Alexa Fluor 594 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details
Human Kaninchen Cy5 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
Details
Human Kaninchen Cy7 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
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Human Kaninchen HRP IHC (p), WB   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
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Human Kaninchen Cy5.5 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
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Human Kaninchen Cy3 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
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Human Kaninchen FITC IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$405.90
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LONP1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Lon Peptidase 1, Mitochondrial Antikörper

  1. Human Polyclonal LONP1 Primary Antibody für WB - ABIN1881504 : Merra, Lago, Ricci, Antuzzi, Gasbarrini, Gasbarrini, Ghirlanda: Splenomegaly as a primary manifestation of Gaucher disease in a young adult woman. in Case reports in gastroenterology 2011 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal LONP1 Primary Antibody für ICC, IF - ABIN4331301 : Gozal, Duong, Gearing, Cheng, Hanfelt, Funderburk, Peng, Lah, Levey: Proteomics analysis reveals novel components in the detergent-insoluble subproteome in Alzheimer's disease. in Journal of proteome research 2009 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen Lon Peptidase 1, Mitochondrial Interaktionspartner

Human Lon Peptidase 1, Mitochondrial (LONP1) Interaktionspartner

  1. Lon preferentially degrades the phosphorylated subunits of CcO (zeige RYR1 Antikörper) and plays a role in the regulation of CcO (zeige RYR1 Antikörper) activity in hypoxia and ischemia/reperfusion injury.

  2. Lon protease (Lonp1), which is a key inductive of mitochondrial unfolded protein response (UPR(mt)) and is required to maintain the mitochondrial quality, was greatly induced in H. pylori infected gastric epithelial cells.

  3. Mutations of Lon, which likely impair its chaperone properties, are at the basis of a genetic inherited disease named the cerebral, ocular, dental, auricular, skeletal (CODAS) syndrome. (Review)

  4. Inhibition of Lon protease by triterpenoids alters mitochondria and is associated to cell death in human cancer cells.

  5. Lon downregulation attenuated hypoxia-induced cardiomyocyte apoptosis through a reduction of reactive oxygen species level.

  6. LONP1 encodes an enzyme of bacterial ancestry that participates in protein turnover within the mitochondrial matrix, and mutations in its ATP-binding and proteolytic domains cause CODAS syndrome.

  7. A review on the recent discoveries concerning Lon Protease functions. [review]

  8. These results suggest that the mechanism underlying cell survival regulated by Lon is mediated by the maintenance of the protein stability of Hsp60 (zeige HSPD1 Antikörper)-mtHsp70 (zeige HSPA9 Antikörper) complex.

  9. Silencing of SIRT3 (zeige SIRT3 Antikörper) increased the levels of Lon protein and of its acetylation, suggesting that Lon is a target of SIRT3 (zeige SIRT3 Antikörper), likely at K917.

  10. We establish a link between LONP1 and CODAS syndrome in humans.

Mouse (Murine) Lon Peptidase 1, Mitochondrial (LONP1) Interaktionspartner

  1. Lon preferentially degrades the phosphorylated subunits of CcO (zeige RYR1 Antikörper) and plays a role in the regulation of CcO (zeige RYR1 Antikörper) activity in hypoxia and ischemia/reperfusion injury.

  2. Lon protease (Lonp1), which is a key inductive of mitochondrial unfolded protein response (UPR(mt)) and is required to maintain the mitochondrial quality, was greatly induced in H. pylori infected gastric epithelial cells.

  3. LONP1 knockdown inhibits cellular proliferation and tumor and metastasis formation, whereas its overexpression increases tumorigenesis.

  4. Epidermal growth factor (zeige EGF Antikörper) up-regulates the transcription of ATP-dependent protease through extracellular signal-regulated protein kinase (zeige CDK7 Antikörper)- and 1-phosphatidylinositol 3-kinase (zeige PIK3CG Antikörper)-dependent pathways.

  5. Modulation of Lon protease activity during aging and oxidative stress.

  6. The correlative effect of Lon and ClpP (zeige CLPP Antikörper) upregulation on loss of mitochondrial Fe-S proteins during the progression of the disease may suggest that Fe-S proteins are potential targets of Lon and ClpP (zeige CLPP Antikörper) proteases in FRDA (zeige FXN Antikörper).

Lon Peptidase 1, Mitochondrial (LONP1) Antigen-Profil

Protein Überblick

This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene.

Genbezeichner und Symbole assoziert mit LONP1

  • lon peptidase 1, mitochondrial (LONP1) Antikörper
  • lon peptidase 1, mitochondrial (lonp1) Antikörper
  • lon peptidase 1, mitochondrial (Lonp1) Antikörper
  • Mitochondrial protease (PIM1) Antikörper
  • 1200017E13Rik Antikörper
  • fc64d11 Antikörper
  • hLON Antikörper
  • Lon Antikörper
  • LonHS Antikörper
  • LONP Antikörper
  • PIM1 Antikörper
  • Prss15 Antikörper
  • wu:fc64d11 Antikörper

Bezeichner auf Proteinebene für LONP1

lon peptidase 1, mitochondrial , protease, serine, 15 , lon protease homolog, mitochondrial-like , hLON ATP-dependent protease , lon protease homolog, mitochondrial , mitochondrial ATP-dependent protease Lon , mitochondrial lon protease-like protein , serine protease 15 , LONP , lon protease-like protein , ATP-dependent Lon protease , hypothetical protein

GENE ID SPEZIES
455623 Pan troglodytes
563257 Danio rerio
100024990 Monodelphis domestica
100074993 Ornithorhynchus anatinus
100408135 Callithrix jacchus
100468447 Ailuropoda melanoleuca
100538450 Meleagris gallopavo
100590941 Nomascus leucogenys
9361 Homo sapiens
74142 Mus musculus
170916 Rattus norvegicus
768942 Gallus gallus
611425 Canis lupus familiaris
100511917 Sus scrofa
510796 Bos taurus
3640999 Candida albicans SC5314
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