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LNX1 encodes a membrane-bound protein that is involved in signal transduction and protein interactions. Zusätzlich bieten wir Ihnen LNX1 Antikörper (51) und LNX1 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.
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Bozozok (Boz, also known as Dharma or Nieuwkoid) as a binding partner and substrate of Lnx-l.
These findings provide functional insights into the LNX protein family, particularly the neuronal LNX1p70 isoform.
the PDZ domain-containing protein (zeige USH1C ELISA Kits) ligand-of-numb protein (zeige NUMBL ELISA Kits)-X (LNX) is found in complex with the coxsackievirus and adenovirus receptor (zeige CXADR ELISA Kits) (CAR)
LNX1 may play a role in regulating (zeige ERBB2 ELISA Kits) neuregulin-1/ErbB signaling in perisynaptic Schwann cells.
LNX1 provides an endocytic scaffold for JAM4 (zeige IGSF5 ELISA Kits) that is implicated in the reorganization of cell junctions.
LNX was closely related to human gliomas and suggested it plays an important role in gliomas by notch (zeige NOTCH1 ELISA Kits) signaling.
LNX1-mediated ubiquitination and degradation of PBK (zeige PBK ELISA Kits) inhibited cell proliferation and enhanced sensitivity to doxorubicin-induced apoptosis.
identify and confirm six novel LNX1 binding partners: KCNA4 (zeige KCNA4 ELISA Kits), PAK6 (zeige PAK6 ELISA Kits), PLEKHG5 (zeige PLEKHG5 ELISA Kits), PKC-alpha1, TYK2 (zeige TYK2 ELISA Kits) and PBK (zeige PBK ELISA Kits), and suggest that LNX1 functions as a signalling scaffold.
The authors found a high level of LNX1 and LNX2 mRNAs in endocarditis, the principal manifestation of chronic Q fever, but not in acute Q fever.
LNX1 and LNX2 interact with CD8alpha and promote its ubiquitylation and endocytosis
Down-regulation of LNX could result in cell cycle arrest in G0/G1 phase through inhibition of beta-catenin (zeige CTNNB1 ELISA Kits), MAPK (zeige MAPK1 ELISA Kits), NFkappaB (zeige NFKB1 ELISA Kits), c-Myc (zeige MYC ELISA Kits)-dependent pathway and activation of p53 (zeige TP53 ELISA Kits), TGF-beta (zeige TGFB1 ELISA Kits)-dependent pathway.
LNX and RhoC (zeige RHOC ELISA Kits) might be part of a larger protein complex that would have important functions in signaling transduction about regulating the transcriptional activities of AP-1 (zeige FOSB ELISA Kits).
identifed ligand of Numb protein (zeige NUMBL ELISA Kits) X as an Np9-interacting partner; findings point to the possibility that Np9 affects tumorigenesis through the LNX/Numb (zeige NUMB ELISA Kits)/Notch (zeige NOTCH1 ELISA Kits) pathway
The presence of multiple protein binding domains involved in signal transduction and interaction with Numb (zeige NUMB ELISA Kits) and SKIP suggested an important role for LNX in tumorogenesis.
The interaction of c-Src with LNX1 depends on the C-terminal PDZ ligand of c-Src.
This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene.
ligand of numb-protein X 1
, multi-PDZ-domain-containing protein
, E3 ubiquitin-protein ligase LNX
, E3 ubiquitin-protein ligase LNX-like
, e3 ubiquitin-protein ligase LNX-like
, ligand of Numb protein X 1
, ligand of Numb-binding protein 1
, numb-binding protein 1
, PDZ domain-containing ring finger protein 2
, multi-PDZ-domain-containing protein, E3 ubiquitin-protein ligase LNX