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LNX1 encodes a membrane-bound protein that is involved in signal transduction and protein interactions. Zusätzlich bieten wir Ihnen LNX1 Proteine (4) und LNX1 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal LNX1 Primary Antibody für ELISA - ABIN408672
Chen, Xu, Zhao, Hu, Cheng, Kang, Xie, Lu: Characterization of human LNX, a novel ligand of Numb protein X that is downregulated in human gliomas. in The international journal of biochemistry & cell biology 2005
Bozozok (Boz, also known as Dharma or Nieuwkoid) as a binding partner and substrate of Lnx-l.
These findings provide functional insights into the LNX protein family, particularly the neuronal LNX1p70 isoform.
the PDZ domain-containing protein (zeige USH1C Antikörper) ligand-of-numb protein (zeige NUMBL Antikörper)-X (LNX) is found in complex with the coxsackievirus and adenovirus receptor (zeige CXADR Antikörper) (CAR)
LNX1 may play a role in regulating (zeige ERBB2 Antikörper) neuregulin-1/ErbB signaling in perisynaptic Schwann cells.
LNX1 provides an endocytic scaffold for JAM4 (zeige IGSF5 Antikörper) that is implicated in the reorganization of cell junctions.
study provided the evidences that LNX1 signaling plays important roles in regulating the stemness of colon cancer cells
LNX was closely related to human gliomas and suggested it plays an important role in gliomas by notch (zeige NOTCH1 Antikörper) signaling.
LNX1-mediated ubiquitination and degradation of PBK (zeige PBK Antikörper) inhibited cell proliferation and enhanced sensitivity to doxorubicin-induced apoptosis.
identify and confirm six novel LNX1 binding partners: KCNA4 (zeige KCNA4 Antikörper), PAK6 (zeige PAK6 Antikörper), PLEKHG5 (zeige PLEKHG5 Antikörper), PKC (zeige PRRT2 Antikörper)-alpha1, TYK2 (zeige TYK2 Antikörper) and PBK (zeige PBK Antikörper), and suggest that LNX1 functions as a signalling scaffold.
The authors found a high level of LNX1 and LNX2 mRNAs in endocarditis, the principal manifestation of chronic Q fever, but not in acute Q fever.
LNX1 and LNX2 interact with CD8alpha and promote its ubiquitylation and endocytosis
Down-regulation of LNX could result in cell cycle arrest in G0/G1 phase through inhibition of beta-catenin (zeige CTNNB1 Antikörper), MAPK (zeige MAPK1 Antikörper), NFkappaB (zeige NFKB1 Antikörper), c-Myc (zeige MYC Antikörper)-dependent pathway and activation of p53 (zeige TP53 Antikörper), TGF-beta (zeige TGFB1 Antikörper)-dependent pathway.
LNX and RhoC (zeige RHOC Antikörper) might be part of a larger protein complex that would have important functions in signaling transduction about regulating the transcriptional activities of AP-1 (zeige FOSB Antikörper).
identifed ligand of Numb protein (zeige NUMBL Antikörper) X as an Np9-interacting partner; findings point to the possibility that Np9 affects tumorigenesis through the LNX/Numb (zeige NUMB Antikörper)/Notch (zeige NOTCH1 Antikörper) pathway
The presence of multiple protein binding domains involved in signal transduction and interaction with Numb (zeige NUMB Antikörper) and SKIP suggested an important role for LNX in tumorogenesis.
This gene encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene.
ligand of numb-protein X 1
, multi-PDZ-domain-containing protein
, E3 ubiquitin-protein ligase LNX
, E3 ubiquitin-protein ligase LNX-like
, e3 ubiquitin-protein ligase LNX-like
, ligand of Numb protein X 1
, ligand of Numb-binding protein 1
, numb-binding protein 1
, PDZ domain-containing ring finger protein 2
, multi-PDZ-domain-containing protein, E3 ubiquitin-protein ligase LNX