anti-Leupaxin (LPXN) Antikörper

The product encoded by LPXN is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Zusätzlich bieten wir Ihnen Leupaxin Proteine (5) und Leupaxin Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
LPXN 9404 O60711
LPXN 107321 Q99N69
LPXN 293783  
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Showing 10 out of 52 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti-Leupaxin antibody, IHC(P) IHC(P): Rat Spleen Tissue Anti-Leupaxin antibody, IHC(P) IHC(P): Mouse Spleen Tissue 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
298,57 €
Details
Human Kaninchen Unkonjugiert WB LPXN Antibody (Center)  western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the LPXN antibody detected the LPXN protein (arrow). Western blot analysis of LPXN (arrow) using rabbit polyclonal LPXN Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the LPXN gene. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of various cells, using LPXN antibody. 100 μL Anmelden zum Anzeigen 12 Days
261,90 €
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: Leupaxin Antibody [NBP2-31078] - Staining of human cell line U-251 MG shows positivity in cytoplasm. Western Blot: Leupaxin Antibody [NBP2-31078] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted).Lane 5: Human liver tissue.Lane 6: Human tonsil tissue 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert ICC, IF, WB Western Blot: Leupaxin Antibody  - Western blot analysis in human cell line RT-4, human cell line U-251 MG, human plasma, human liver tissue and human tonsil tissue. Immunocytochemistry/Immunofluorescence: Leupaxin Antibody  - Staining of human cell line U-2 OS shows localization to nuclear speckles, cytosol & focal adhesion sites. 100 μL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB   100 μg Anmelden zum Anzeigen 11 bis 14 Tage
548,26 €
Details
Human Kaninchen Alexa Fluor 350 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Alexa Fluor 488 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Alexa Fluor 555 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
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Human Kaninchen Alexa Fluor 594 IF (p)   100 μL Anmelden zum Anzeigen 18 bis 22 Tage
414,64 €
Details

LPXN Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Weitere Antikörper gegen Leupaxin Interaktionspartner

Human Leupaxin (LPXN) Interaktionspartner

  1. this is the first demonstration of a role for the leupaxin in the regulation of hepatocellular carcinoma progression, at least in part, by enhancing beta-catenin (zeige CTNNB1 Antikörper) transcription activity.

  2. The full-length leupaxin binds to the Pyk2 (zeige PTK2B Antikörper)-focal adhesion targeting domain.

  3. Authors demonstrate that LPXN directly influences cytoskeletal dynamics via interaction with the actin-binding protein (zeige KPTN Antikörper) CaD (zeige CAD Antikörper) and regulates CaD (zeige CAD Antikörper) phosphorylation by recruiting ERK (zeige EPHB2 Antikörper) to highly dynamic structures within PCa (zeige FLVCR1 Antikörper) cells.

  4. Results show that leupaxin has particular influence on the progression and invasion of breast cancer cells and may therefore represent an interesting candidate protein for diagnosis and therapeutic interventions.

  5. first evidence of dynamic regulation of leupaxin localization and tyrosine phosphorylation by G-Protein Coupled Receptors

  6. leupaxin functions as a paxillin (zeige PXN Antikörper) counterpart that potently suppresses the tyrosine phosphorylation of paxillin (zeige PXN Antikörper) during integrin signaling.

  7. leupaxin may be a critical nucleating component of the osteoclast podosomal signaling complex

  8. Leupaxin binding to tyrosine phosphatase PEP suggests that leupaxin may function as a signal-transducing complex with PEP.

  9. These data demonstrate that LPXN forms a signaling complex with Pyk2 (zeige PTK2B Antikörper), c-Src (zeige SRC Antikörper), and PTP-PEST (zeige PTPN12 Antikörper) to regulate migration of prostate cancer cells.

  10. Leupaxin plays an inhibitory role in BCR (zeige BCR Antikörper) signaling and B cell function.

Mouse (Murine) Leupaxin (LPXN) Interaktionspartner

  1. leupaxin functions as a paxillin (zeige PXN Antikörper) counterpart that potently suppresses the tyrosine phosphorylation of paxillin (zeige PXN Antikörper) during integrin signaling.

  2. leupaxin may be a critical nucleating component of the osteoclast podosomal signaling complex

  3. Association of the scaffold protein (zeige HOMER1 Antikörper) LPXN with Src (zeige SRC Antikörper) adds further complexity to the organization of the podosomal signaling complex in osteoclasts.

  4. Leupaxin plays an inhibitory role in BCR (zeige BCR Antikörper) signaling and B cell function.

  5. Leupaxin is enriched in mouse vascular smooth muscle and its expression is dynamically regulated during development.

Leupaxin (LPXN) Antigen-Profil

Protein Überblick

The product encoded by this gene is preferentially expressed in hematopoietic cells and belongs to the paxillin protein family. Similar to other members of this focal-adhesion-associated adaptor-protein family, it has four leucine-rich LD-motifs in the N-terminus and four LIM domains in the C-terminus. It may function in cell type-specific signaling by associating with PYK2, a member of focal adhesion kinase family. As a substrate for a tyrosine kinase in lymphoid cells, this protein may also function in, and be regulated by, tyrosine kinase activity. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Genbezeichner und Symbole assoziert mit anti-Leupaxin (LPXN) Antikörper

  • leupaxin (LPXN) Antikörper
  • si:rp71-15d4.1 (si:rp71-15d4.1) Antikörper
  • leupaxin (PAAG_03110) Antikörper
  • leupaxin (PGTG_11441) Antikörper
  • Leupaxin (lpxn) Antikörper
  • leupaxin (Lpxn) Antikörper
  • 4933402K05Rik Antikörper
  • A530083L21Rik Antikörper
  • AV278559 Antikörper
  • LDPL Antikörper
  • MGC140379 Antikörper

Bezeichner auf Proteinebene für anti-Leupaxin (LPXN) Antikörper

leupaxin , Leupaxin

GENE ID SPEZIES
281277 Bos taurus
423129 Gallus gallus
451205 Pan troglodytes
483465 Canis lupus familiaris
513264 Bos taurus
560743 Danio rerio
702033 Macaca mulatta
9097993 Paracoccidioides sp. 'lutzii' Pb01
10527262 Puccinia graminis f. sp. tritici CRL 75-36-700-3
100066577 Equus caballus
100196515 Salmo salar
100394284 Callithrix jacchus
100445873 Pongo abelii
100592030 Nomascus leucogenys
9404 Homo sapiens
107321 Mus musculus
293783 Rattus norvegicus
100008712 Oryctolagus cuniculus
Ausgewählte Anbieter für anti-Leupaxin (LPXN) Antikörper
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