Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1) ELISA Kits

LRSAM1 encodes a ring finger protein involved in a variety of functions, including regulation of signaling pathways and cell adhesion, mediation of self-ubiquitylation, and involvement in cargo sorting during receptor endocytosis. Zusätzlich bieten wir Ihnen LRSAM1 Antikörper (47) und LRSAM1 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
LRSAM1 90678 Q6UWE0
LRSAM1 227738 Q80ZI6
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Top LRSAM1 ELISA Kits auf antikoerper-online.de

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Katalog Nr. Reaktivität Sensitivität Bereich Menge Anbieter Lieferzeit Preis Details
Human
96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
788,70 €
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Maus
96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
788,70 €
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Weitere ELISA Kits für LRSAM1 Interaktionspartner

Human Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1) Interaktionspartner

  1. findings suggest that the mutant LRSAM1 may aberrantly affect the formation of transcription machinery.

  2. findings demonstrate that the isolated genetic entity Charcot-Marie-Tooth type 2G is caused by a missense mutation in LRSAM1.

  3. LRSAM1 exhibited self-association in vitro and in vivo. The study found the self-association of LRSAM1 promotes intermolecular ubiquitination and proved a potential N-terminal ubiquitination.

  4. Plant homeodomain finger protein 23 negatively regulates cell autophagy by promoting ubiquitination and degradation of E3 ligase LRSAM1

  5. disruption of the C-terminal RING domain confers dominant negative properties to LRSAM1

  6. Our data further confirms that LRSAM1 mutations are associated with CMT2 of AD inheritance.

  7. Authors identify LRSAM1 as the E3 ligase responsible for anti-Salmonella autophagy-associated ubiquitination.

  8. homozygous mutation in LRSAM1 was proposed as a strong candidate for the disease in a family with recessive axonal polyneuropathy

  9. LRSAM1 as a component of the antibacterial autophagic response.

  10. LRSAM1 is a strong candidate for the causal gene for the Charcot-Marie-Tooth disease.

Mouse (Murine) Leucine Rich Repeat and Sterile alpha Motif Containing 1 (LRSAM1) Interaktionspartner

  1. TLR4 (zeige TLR4 ELISA Kits)/NF-kappaB (zeige NFKB1 ELISA Kits)-responsive microRNAs and their potential target genes: a mouse model of skeletal muscle ischemia-reperfusion injury.

  2. Lrsam1 mutant mice are more sensitive to challenge with acrylamide, a neurotoxic agent that causes axon degeneration, indicating that the axons in the mutant mice are indeed compromised.

LRSAM1 Antigen-Profil

Beschreibung des Gens

This gene encodes a ring finger protein involved in a variety of functions, including regulation of signaling pathways and cell adhesion, mediation of self-ubiquitylation, and involvement in cargo sorting during receptor endocytosis. Mutations in this gene have been associated with Charcot-Marie-Tooth disease. Multiple transcript variants encoding different isoforms have been identified for this gene.

Genbezeichner und Symbole assoziert mit LRSAM1

  • leucine rich repeat and sterile alpha motif containing 1 (LRSAM1) Antikörper
  • leucine rich repeat and sterile alpha motif containing 1 (Lrsam1) Antikörper
  • CMT2P Antikörper
  • RIFLE Antikörper
  • TAL Antikörper

Bezeichner auf Proteinebene für LRSAM1

E3 ubiquitin-protein ligase LRSAM1 , Tsg101-associated ligase , leucine-rich repeat and sterile alpha motif-containing protein 1 , tsg101-associated ligase

GENE ID SPEZIES
90678 Homo sapiens
227738 Mus musculus
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