anti-Left-Right Determination Factor 2 (LEFTY2) Antikörper

LEFTY2 encodes a member of the TGF-beta family of proteins. Zusätzlich bieten wir Ihnen LEFTY2 Proteine (11) und LEFTY2 Kits (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
LEFTY2 13590 Q64280
LEFTY2 7044 O00292
LEFTY2 289316  
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Top anti-LEFTY2 Antikörper auf antikoerper-online.de

Showing 10 out of 60 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-LEFTY2 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>RPMI 8226 cell lysate Immunohistochemistry with Uterus tissue at an antibody concentration of 5µg/ml using anti-LEFTY2 antibody (ARP42107_P050) 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Maus Unkonjugiert EIA, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$411.18
Details
Hund Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti-LEFTY2 antibody IHC staining of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959060 concentration 5 ug/ml. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$676.50
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of various cells, using LEFTY2 antibody. 100 μL Anmelden zum Anzeigen 16 Days
$323.13
Details
Human Kaninchen Unkonjugiert IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: A431 , 10% SDS PAGE antibody diluted at 1:1000 IHC-P Image Immunohistochemical analysis of paraffin-embedded human colon carcinoma, using LEFTY2, antibody at 1:500 dilution. 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Maus Kaninchen Unkonjugiert ICC, IHC, IP, WB 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$360.00
Details
Human Maus Unkonjugiert IHC, ELISA, WB 0.05 mg Anmelden zum Anzeigen 2 bis 3 Tage
$515.63
Details
Human Maus Unkonjugiert IHC (p), ELISA, WB 50 μg Anmelden zum Anzeigen 6 bis 7 Tage
$541.80
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$433.13
Details

LEFTY2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine) ,
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Weitere Antikörper gegen LEFTY2 Interaktionspartner

Zebrafish Left-Right Determination Factor 2 (LEFTY2) Interaktionspartner

  1. results indicate that differential diffusivity is the major determinant of the differences in Nodal/Lefty range and provide biophysical support for reaction-diffusion models of activator/inhibitor-mediated patterning

  2. we find that Cyclops is specifically required for the maintenance of lefty1 (zeige LEFTY1 Antikörper) and lefty2 transcription

  3. study reports that microRNA-430 (miR (zeige MYLIP Antikörper)-430) dampens and balances the expression of the transforming growth factor-beta (TGF-beta) Nodal agonist squint and the TGF-beta (zeige TGFB1 Antikörper) Nodal antagonist lefty

Mouse (Murine) Left-Right Determination Factor 2 (LEFTY2) Interaktionspartner

  1. results show that TET-mediated oxidation of 5-methylcytosine modulates Lefty-Nodal signalling by promoting demethylation in opposition to methylation by DNMT3A (zeige DNMT3A Antikörper) and DNMT3B (zeige DNMT3B Antikörper); findings reveal a fundamental epigenetic mechanism featuring dynamic DNA methylation (zeige HELLS Antikörper) and demethylation crucial to regulation of key signalling pathways in early body plan formation

  2. LEFTY2 regulates the expression and activity of ENaC (zeige SCNN1A Antikörper) in endometrial epithelial cells via SGK1 (zeige SGK1 Antikörper).

  3. Results indicate that microRNA miR (zeige MLXIP Antikörper)-127 accelerates mesendoderm differentiation of embryonic stem cells through nodal signaling by targeting left-right determination factor 2 (Lefty2).

  4. exogenous lefty1 (zeige LEFTY1 Antikörper) administered to mice restored the endogenous expression levels of lefty1 (zeige LEFTY1 Antikörper). The present study demonstrated that lefty1 (zeige LEFTY1 Antikörper) attenuated renal interstitial injury by inhibiting the Smaddependent TGFb1 (zeige TGFB1 Antikörper) signaling pathway

  5. Lefty-1 (zeige LEFTY1 Antikörper) may prevent TGFB1 (zeige TGFB1 Antikörper)-induced fibroblast-myofibroblast transdifferentiation in part via modulation of Smad3 (zeige SMAD3 Antikörper), JNK-3 (zeige MAPK10 Antikörper), and BMP-5 (zeige BMP5 Antikörper) signaling.

  6. The expression of lefty in RCC (zeige XRCC1 Antikörper) cells was lower than that in adjacent non-tumor cells, which may result in the overexpression of nodal, thereby promoting the growth of RCC (zeige XRCC1 Antikörper).

  7. Studies indicate that the pair of Nodal and Lefty (Lefty1 and Lefty2) has a conserved role in left-right asymmetry.

  8. Taken together, these results suggest that optimal expression of Lefty1 (zeige LEFTY1 Antikörper) and Lefty2 is critical for the balanced differentiation of mESCs into three germ layers.

  9. Beta-catenin (zeige CTNNB1 Antikörper) can recruit the H3K4me2/1 demethylase (zeige MBD2 Antikörper) LSD1 (zeige KDM1A Antikörper) to regulate the expression of the tumor suppressor Lefty1 (zeige LEFTY1 Antikörper) in mouse embryonic stem cells.

  10. Lefty can antagonise TGF-beta1 (zeige TGFB1 Antikörper) mediated epithelial-mesenchymal transition in renal tubular epithelial cells.

Human Left-Right Determination Factor 2 (LEFTY2) Interaktionspartner

  1. LEFTY2 down-regulates MKi67 (zeige MKI67 Antikörper) expression and FAK (zeige PTK2 Antikörper) activity, up-regulates miR (zeige MLXIP Antikörper)-200a and E-cadherin (zeige CDH1 Antikörper), and is thus a powerful negative regulator of endometrial cell proliferation and migration.

  2. LEFTY2 regulates the expression and activity of ENaC (zeige SCNN1A Antikörper) in endometrial epithelial cells via SGK1 (zeige SGK1 Antikörper).

  3. Lefty A may account for the tumor suppressive activity of human adult stem cells.

  4. Findings suggest that Lefty2 is negatively modulated by miR (zeige MLXIP Antikörper)-302s in hESCs, which plays an important role in maintaining the balance between pluripotency and germ layer specification.

  5. findings show that the TGFB4 (ebaf) mRNA has distinct tumor specific expression

  6. nodal and the inhibitors of Nodal signaling, lefty-A and lefty-B, are down-regulated very early upon differentiation of human embryonic stem cells

  7. Addition of recombinant LEFTY-A to explants induced MMP-9 (zeige MMP9 Antikörper) in most samples, a response prevented by ovarian steroids.

  8. LEFTY proteins, which are known to play a major role during mouse gastrulation, are transiently expressed during human embryonic stem cell differentiation.

LEFTY2 Antigen-Profil

Protein Überblick

This gene encodes a member of the TGF-beta family of proteins. The encoded protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. The protein may also play a role in endometrial bleeding. Mutations in this gene have been associated with left-right axis malformations, particularly in the heart and lungs. Some types of infertility have been associated with dysregulated expression of this gene in the endometrium. Alternative processing of this protein can yield three different products. This gene is closely linked to both a related family member and a related pseudogene. Alternate splicing of this gene results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit LEFTY2

  • lefty2 (lft2) Antikörper
  • left-right determination factor 2 (LEFTY2) Antikörper
  • left-right determination factor 1 (LOC490387) Antikörper
  • left-right determination factor 2 (LOC699676) Antikörper
  • left-right determination factor 2-like (LOC100232580) Antikörper
  • left right determination factor 1 (Lefty1) Antikörper
  • left-right determination factor 2 (Lefty2) Antikörper
  • Left-right determination factor 2 (Lefty2) Antikörper
  • 6030463A22Rik Antikörper
  • AI450052 Antikörper
  • atv2 Antikörper
  • AV214969 Antikörper
  • cb720 Antikörper
  • EBAF Antikörper
  • Ebaf2 Antikörper
  • fe38b03 Antikörper
  • Lefta Antikörper
  • Leftb Antikörper
  • lefty Antikörper
  • lefty-1 Antikörper
  • LEFTY1 Antikörper
  • LEFTYA Antikörper
  • Stra3 Antikörper
  • TGFB4 Antikörper
  • wu:fe38b03 Antikörper

Bezeichner auf Proteinebene für LEFTY2

lefty , endometrial bleeding associated factor , left-right determination factor 1 , left-right determination factor 2 , left-right determination factor 2-like , TGF-beta-4 , left-right determination, factor B , protein lefty-1 , stimulated by retinoic acid gene 3 protein , transforming growth factor beta-4 , endometrial bleeding-associated factor , left-right determination factor A , protein lefty-2 , protein lefty-A , left-right determination factor B , left-right determination, factor A , protein lefty-B

GENE ID SPEZIES
30146 Danio rerio
395529 Gallus gallus
457780 Pan troglodytes
490387 Canis lupus familiaris
699676 Macaca mulatta
100232580 Taeniopygia guttata
100435327 Pongo abelii
13590 Mus musculus
7044 Homo sapiens
320202 Mus musculus
289316 Rattus norvegicus
100337677 Sus scrofa
534018 Bos taurus
Ausgewählte Anbieter für anti-LEFTY2 (LEFTY2) Antikörper
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