Lectin, Galactoside-Binding, Soluble, 8 Proteine (LGALS8)

LGALS8 encodes a member of the galectin family. Zusätzlich bieten wir Ihnen Lectin, Galactoside-Binding, Soluble, 8 Antikörper (100) und Lectin, Galactoside-Binding, Soluble, 8 Kits (52) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
LGALS8 56048 Q9JL15
LGALS8 3964 O00214
LGALS8 116641  
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Top Lectin, Galactoside-Binding, Soluble, 8 Proteine auf antikoerper-online.de

Showing 10 out of 26 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,331.68
Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,331.68
Details
Escherichia coli (E. coli) Human His tag 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$295.00
Details
Escherichia coli (E. coli) Maus His tag 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$295.00
Details
Escherichia coli (E. coli) Maus His tag 50 μg Anmelden zum Anzeigen 15 bis 19 Tage
$319.00
Details
Escherichia coli (E. coli) Ratte GST tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
Details
Escherichia coli (E. coli) Human GST tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
$382.80
Details
Escherichia coli (E. coli) Human His tag 50 μg Anmelden zum Anzeigen 15 bis 19 Tage
$319.00
Details
Escherichia coli (E. coli) Ratte His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$704.00
Details
Wheat germ Human GST tag   10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$405.71
Details

LGALS8 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)
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Human , ,
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Rat (Rattus) ,
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Am meisten referenzierte Lectin, Galactoside-Binding, Soluble, 8 Proteine

  1. Human LGALS8 Protein expressed in Wheat germ - ABIN1309342 : Mao, Ladd, Gad, Rastetter, Johnson, Marzbani, Childs, Lu, Dang, Broussard, Stanton, Hanash, Disis: Mining the pre-diagnostic antibody repertoire of TgMMTV-neu mice to identify autoantibodies useful for the early detection of human breast cancer. in Journal of translational medicine 2014 (PubMed)

Weitere Proteine zu Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) Interaktionspartnern

Mouse (Murine) Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) Interaktionspartner

  1. Galectin-8 activates dendritic cells and stimulates antigen-specific immune response elicitation.

  2. these data suggest that Gal-8 promotes the differentiation of highly suppressive Treg cells, which has implications for the treatment of inflammatory and autoimmune diseases.

  3. this study uncovers a unique molecular mechanism of lymphangiogenesis in which galectin-8-dependent crosstalk among VEGF-C (zeige VEGFC Proteine), podoplanin (zeige PDPN Proteine) and integrin pathways plays a key role.

  4. Gal (zeige GAL Proteine)-8mut was unable to induce T-cell proliferation, but efficiently co-stimulated antigen-specific responses, bothin vitroandin vivo.

  5. Gal-8 emerges as an attractive therapeutic candidate.

  6. Galectin-8 induces RANKL (zeige TNFSF11 Proteine) expression, osteoclastogenesis, and bone mass reduction in mice.

  7. Gal-8 stimulated naive T cells, but had an antiproliferative effect when these cells were activated.A dose of recombinant Gal-8 administered with a suboptimal Ag dose to DO11.10 mice strengthened weak responses in vivo.

  8. a novel role for Gal-8 in collaboration with Gal-1 (zeige LGALS1 Proteine) in plasma cell formation, and suggest the possibility of using distinct LacNAc ligands to modulate the function of Gals.

  9. The findings of the present study delineate the differential molecular requirements for Gal-8 activities on T-cells, and suggest a dual activity relying on activation state.

  10. downstream effectors of PI3K, including PKB (zeige AKT2 Proteine) and p70 S6 kinase (zeige PRKACB Proteine), in part mediate cell adhesion, spreading, and microspike formation induced by galectin-8

Human Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) Interaktionspartner

  1. Our data indicate that Gal-8 interacts with ALCAM at the surface of breast cancer cells through glycosylation-dependent mechanisms. A novel heterophilic interaction between ALCAM and Gal-8 is demonstrated here, suggesting its physiologic relevance in the biology of breast cancer cells

  2. we detected Gal-8 in human cerebrospinal fluid, suggesting a role in the CNS immune-surveillance circuit. In addition, we show that MS patients generate function-blocking anti-Gal-8 antibodies with pathogenic potential. Furthermore, circulating anti-Gal-8 antibodies associate with relapsing-remitting MS, and not with progressive MS phenotypes, predicting clinical disability at diagnosis within the first year of follow-up

  3. Data suggest that galectin-8 is a potential independent favorable prognostic biomarker for survival and recurrence of patients with gastric cancer after surgery.

  4. this study uncovers a unique molecular mechanism of lymphangiogenesis in which galectin-8-dependent crosstalk among VEGF-C (zeige VEGFC Proteine), podoplanin (zeige PDPN Proteine) and integrin pathways plays a key role.

  5. Platelet-derived factor V/Va is generated following endocytosis of the plasma-derived molecule by the platelet precursor cells, megakaryocytes, via a two receptor system consisting of LRP-1 (zeige LRP1 Proteine) and an unidentified specific "binding site".

  6. Gal-8 expression is a potential independent unfavorable prognostic indicator for postoperative recurrence of patients with localized pT1 clear cell renal cell carcinoma (zeige MOK Proteine)

  7. The fundamental roles of galectin-8 in human anaplastic large cell lymphoma

  8. The implications of gal-8 in tumor angiogenesis remain to be further explored, but it is exciting to speculate that modulating gal-8-glycan interactions could be used to block lymphatic-vascular connections vital for metastasis

  9. We integrate here the available information on Gal-8 expression in different tumor types and attempt to elucidate associations of its expression and localization with tumor progression[review]

  10. these results not only confirm the pro-inflammatory role we have already proposed for Gal-8 in other cellular systems but also suggest that this lectin is orchestrating the interaction between leukocytes, platelets and endothelial cells

Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) Protein Überblick

Protein Überblick

This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified.

Genbezeichner und Symbole assoziert mit LGALS8

  • galectin 8 (LGALS8)
  • lectin, galactose binding, soluble 8 (Lgals8)
  • galectin 8 (Lgals8)
  • lectin, galactoside binding soluble 8 S homeolog (lgals8.S)
  • 1200015E08Rik Protein
  • AI326142 Protein
  • D13Ertd524e Protein
  • Gal-8 Protein
  • galectin-8 Protein
  • Lgals-8 Protein
  • LGALS8 Protein
  • PCTA-1 Protein
  • PCTA1 Protein
  • Po66-CBP Protein
  • xgalectin-VIIIa Protein

Bezeichner auf Proteinebene für LGALS8

lectin, galactoside-binding, soluble, 8 , lectin, galactoside-binding, soluble, 8 (galectin 8) , galectin-8-like , gal-8 , galectin 8 , galectin-8 , galectin-8L , lectin, galactose binding, soluble 5 , galectin-8 variant II , Po66 carbohydrate binding protein , galectin-8g , po66 carbohydrate-binding protein , prostate carcinoma tumor antigen 1 , 30 kDa S-type lectin , RL-30 , lectin, galactose binding, soluble 8 , galectin family xgalectin-VIIIa , xgalectin-VIII

GENE ID SPEZIES
710375 Macaca mulatta
743841 Pan troglodytes
100436942 Pongo abelii
100595058 Nomascus leucogenys
56048 Mus musculus
430948 Gallus gallus
3964 Homo sapiens
479193 Canis lupus familiaris
100156193 Sus scrofa
506977 Bos taurus
116641 Rattus norvegicus
100343919 Oryctolagus cuniculus
100733991 Cavia porcellus
101115850 Ovis aries
398442 Xenopus laevis
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