anti-Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) Antikörper

LGALS8 encodes a member of the galectin family. Zusätzlich bieten wir Ihnen Lectin, Galactoside-Binding, Soluble, 8 Kits (52) und Lectin, Galactoside-Binding, Soluble, 8 Proteine (26) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
LGALS8 56048 Q9JL15
LGALS8 3964 O00214
LGALS8 116641  
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Top anti-Lectin, Galactoside-Binding, Soluble, 8 Antikörper auf antikoerper-online.de

Showing 10 out of 100 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-LGALS8 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>Hela cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, using LEG8 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue, using LEG8 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Maus Unkonjugiert ELISA, WB Detection limit for recombinant GST tagged LGALS8 is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Human Kaninchen Unkonjugiert IHC (p), ELISA, WB Anti-LGALS8 / Galectin-8 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959345 concentration 5 ug/ml. Anti-LGALS8 / Galectin-8 antibody IHC staining of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN959345 concentration 5 ug/ml. 50 μL Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Huhn Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert WB WB Image Sample (30 ug of whole cell lysate) A: Non-transfected 293T lysates B: LGALS8 transfected 293T lysates 10% SDS PAGE antibody diluted at 1:5000 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$292.60
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Tonsil: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Anmelden zum Anzeigen 11 bis 13 Tage
$542.85
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
$175.80
Details
Human Kaninchen Unkonjugiert IC, IF, IHC, WB Immunofluorescent analysis of Galectin 8 staining in HepG2 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of Galectin 8 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details

LGALS8 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Lectin, Galactoside-Binding, Soluble, 8 Antikörper

  1. Human Monoclonal LGALS8 Primary Antibody für Func, IA - ABIN2192096 : Levy, Arbel-Goren, Hadari, Eshhar, Ronen, Elhanany, Geiger, Zick: Galectin-8 functions as a matricellular modulator of cell adhesion. in The Journal of biological chemistry 2001 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen Lectin, Galactoside-Binding, Soluble, 8 Interaktionspartner

Mouse (Murine) Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) Interaktionspartner

  1. Galectin-8 activates dendritic cells and stimulates antigen-specific immune response elicitation.

  2. these data suggest that Gal-8 promotes the differentiation of highly suppressive Treg cells, which has implications for the treatment of inflammatory and autoimmune diseases.

  3. this study uncovers a unique molecular mechanism of lymphangiogenesis in which galectin-8-dependent crosstalk among VEGF-C (zeige VEGFC Antikörper), podoplanin (zeige PDPN Antikörper) and integrin pathways plays a key role.

  4. Gal (zeige GAL Antikörper)-8mut was unable to induce T-cell proliferation, but efficiently co-stimulated antigen-specific responses, bothin vitroandin vivo.

  5. Gal-8 emerges as an attractive therapeutic candidate.

  6. Galectin-8 induces RANKL (zeige TNFSF11 Antikörper) expression, osteoclastogenesis, and bone mass reduction in mice.

  7. Gal-8 stimulated naive T cells, but had an antiproliferative effect when these cells were activated.A dose of recombinant Gal-8 administered with a suboptimal Ag dose to DO11.10 mice strengthened weak responses in vivo.

  8. a novel role for Gal-8 in collaboration with Gal-1 (zeige LGALS1 Antikörper) in plasma cell formation, and suggest the possibility of using distinct LacNAc ligands to modulate the function of Gals.

  9. The findings of the present study delineate the differential molecular requirements for Gal-8 activities on T-cells, and suggest a dual activity relying on activation state.

  10. downstream effectors of PI3K, including PKB (zeige AKT2 Antikörper) and p70 S6 kinase (zeige PRKACB Antikörper), in part mediate cell adhesion, spreading, and microspike formation induced by galectin-8

Human Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) Interaktionspartner

  1. Our data indicate that Gal-8 interacts with ALCAM at the surface of breast cancer cells through glycosylation-dependent mechanisms. A novel heterophilic interaction between ALCAM and Gal-8 is demonstrated here, suggesting its physiologic relevance in the biology of breast cancer cells

  2. we detected Gal-8 in human cerebrospinal fluid, suggesting a role in the CNS immune-surveillance circuit. In addition, we show that MS patients generate function-blocking anti-Gal-8 antibodies with pathogenic potential. Furthermore, circulating anti-Gal-8 antibodies associate with relapsing-remitting MS, and not with progressive MS phenotypes, predicting clinical disability at diagnosis within the first year of follow-up

  3. Data suggest that galectin-8 is a potential independent favorable prognostic biomarker for survival and recurrence of patients with gastric cancer after surgery.

  4. this study uncovers a unique molecular mechanism of lymphangiogenesis in which galectin-8-dependent crosstalk among VEGF-C (zeige VEGFC Antikörper), podoplanin (zeige PDPN Antikörper) and integrin pathways plays a key role.

  5. Platelet-derived factor V/Va is generated following endocytosis of the plasma-derived molecule by the platelet precursor cells, megakaryocytes, via a two receptor system consisting of LRP-1 (zeige LRP1 Antikörper) and an unidentified specific "binding site".

  6. Gal-8 expression is a potential independent unfavorable prognostic indicator for postoperative recurrence of patients with localized pT1 (zeige ZNF77 Antikörper) clear cell renal cell carcinoma (zeige MOK Antikörper)

  7. The fundamental roles of galectin-8 in human anaplastic large cell lymphoma

  8. The implications of gal-8 in tumor angiogenesis remain to be further explored, but it is exciting to speculate that modulating gal-8-glycan interactions could be used to block lymphatic-vascular connections vital for metastasis

  9. We integrate here the available information on Gal-8 expression in different tumor types and attempt to elucidate associations of its expression and localization with tumor progression[review]

  10. these results not only confirm the pro-inflammatory role we have already proposed for Gal-8 in other cellular systems but also suggest that this lectin is orchestrating the interaction between leukocytes, platelets and endothelial cells

Lectin, Galactoside-Binding, Soluble, 8 (LGALS8) Antigen-Profil

Protein Überblick

This gene encodes a member of the galectin family. Galectins are beta-galactoside-binding animal lectins with conserved carbohydrate recognition domains. The galectins have been implicated in many essential functions including development, differentiation, cell-cell adhesion, cell-matrix interaction, growth regulation, apoptosis, and RNA splicing. This gene is widely expressed in tumoral tissues and seems to be involved in integrin-like cell interactions. Alternatively spliced transcript variants encoding different isoforms have been identified.

Genbezeichner und Symbole assoziert mit LGALS8

  • galectin 8 (LGALS8) Antikörper
  • lectin, galactose binding, soluble 8 (Lgals8) Antikörper
  • galectin 8 (Lgals8) Antikörper
  • lectin, galactoside binding soluble 8 S homeolog (lgals8.S) Antikörper
  • 1200015E08Rik Antikörper
  • AI326142 Antikörper
  • D13Ertd524e Antikörper
  • Gal-8 Antikörper
  • galectin-8 Antikörper
  • Lgals-8 Antikörper
  • LGALS8 Antikörper
  • PCTA-1 Antikörper
  • PCTA1 Antikörper
  • Po66-CBP Antikörper
  • xgalectin-VIIIa Antikörper

Bezeichner auf Proteinebene für LGALS8

lectin, galactoside-binding, soluble, 8 , lectin, galactoside-binding, soluble, 8 (galectin 8) , galectin-8-like , gal-8 , galectin 8 , galectin-8 , galectin-8L , lectin, galactose binding, soluble 5 , galectin-8 variant II , Po66 carbohydrate binding protein , galectin-8g , po66 carbohydrate-binding protein , prostate carcinoma tumor antigen 1 , 30 kDa S-type lectin , RL-30 , lectin, galactose binding, soluble 8 , galectin family xgalectin-VIIIa , xgalectin-VIII

GENE ID SPEZIES
710375 Macaca mulatta
743841 Pan troglodytes
100436942 Pongo abelii
100595058 Nomascus leucogenys
56048 Mus musculus
430948 Gallus gallus
3964 Homo sapiens
479193 Canis lupus familiaris
100156193 Sus scrofa
506977 Bos taurus
116641 Rattus norvegicus
100343919 Oryctolagus cuniculus
100733991 Cavia porcellus
101115850 Ovis aries
398442 Xenopus laevis
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