anti-Lactate Dehydrogenase A (LDHA) Antikörper

The protein encoded by LDHA catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. Zusätzlich bieten wir Ihnen Lactate Dehydrogenase A Proteine (56) und Lactate Dehydrogenase A Kits (33) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
LDHA 3939 P00338
LDHA 16828 P06151
LDHA 24533 P04642
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Top anti-Lactate Dehydrogenase A Antikörper auf antikoerper-online.de

Showing 10 out of 249 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB Host: Rabbit Target Name: LDHA Sample Tissue: Human Jurkat, MCF7, 721_B Antibody Dilution: 1.0ug/ml Host: Rabbit Target Name: LDHA Sample Type: Hela Antibody Dilution: 1.0ug/ml  LDHA is supported by BioGPS gene expression data to be expressed in HeLa 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-Ldha Antibody Titration: 1.0 ug/ml Positive Control: Rat Stomach 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Kaninchen Ziege Unkonjugiert EIA, IF, IP, WB Figure 1. Western blot analysis shows anti-Lactate Dehydrogenase antibody detects LDH in HeLa cell extracts. Reactivity with LDH is observed in the cytoplasmic fraction (CF) and little to no reactivity in the nuclear fraction (NF). ~30 µg was loaded per lane onto a 10% gel for SDS-PAGE. Comparison to a molecular weight marker (not shown) indicates a single band of ~36 kDa corresponding to the expected molecular weight for the protein. The blot was incubated with a 1:1,000 dilution of the antibody in 5% milk in TBST at room temperature followed by detection using standard procedures. 2 mL Anmelden zum Anzeigen 6 bis 8 Tage
$1,204.50
Details
Human Kaninchen Unkonjugiert IF, IHC (p), WB LDHA Antibody (C-term) (ABIN657465) western blot analysis in MDA-MB231 cell line lysates (35 µg/lane). This demonstrates the LDHA antibody detected the LDHA protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB LDHA Antibody (Center) (ABIN653476) western blot analysis in Ramos,A375 cell line lysates (35 µg/lane).This demonstrates the LDHA antibody detected the LDHA protein (arrow). Formalin-fixed and paraffin-embedded human skin tissue reacted with LDHA Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert EIA, FACS, IHC (p), WB Flow cytometry analysis of Hela cells using LDHA Antibody (Center) Cat.-No AP52459PU-N (bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Immunohistochemistry analysis in formalin-fixed and paraffin-embedded human skin tissue reacted with LDHA Antibody (Center) Cat.-No AP52459PU-N which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Maus Unkonjugiert EIA, IF, WB 0.1 mL Anmelden zum Anzeigen 6 bis 8 Tage
$412.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB   100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert IF, IHC, WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$245.00
Details

LDHA Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Lactate Dehydrogenase A Antikörper

  1. Human Polyclonal Lactate Dehydrogenase A Primary Antibody für ICC, IF - ABIN4329691 : Adochite, Moshnikova, Carlin, Guerrieri, Andreev, Lewis, Reshetnyak: Targeting breast tumors with pH (low) insertion peptides. in Molecular pharmaceutics 2014 (PubMed)
    Show all 4 Pubmed References

  2. Human Monoclonal Lactate Dehydrogenase A Primary Antibody für ICC, IF - ABIN4329689 : Pizzuto, Paventi, Porcile, Sarnataro, Daniele, Passarella et al.: l-Lactate metabolism in HEP G2 cell mitochondria due to the l-lactate dehydrogenase determines the occurrence of the lactate/pyruvate shuttle and the appearance of oxaloacetate, malate and citrate ... in Biochimica et biophysica acta 2012 (PubMed)
    Show all 2 Pubmed References

  3. Cow (Bovine) Polyclonal Lactate Dehydrogenase A Primary Antibody für IHC, WB - ABIN2774085 : Listerman, Bledau, Grishina, Neugebauer: Extragenic accumulation of RNA polymerase II enhances transcription by RNA polymerase III. in PLoS genetics 2008 (PubMed)

Weitere Antikörper gegen Lactate Dehydrogenase A Interaktionspartner

Horse (Equine) Lactate Dehydrogenase A (LDHA) Interaktionspartner

  1. Molecular characterization and expression pattern of the equine lactate dehydrogenase A genes

Rabbit Lactate Dehydrogenase A (LDHA) Interaktionspartner

  1. Dynamic changes of LDH and HBDH activities may be useful in diagnosis of non-thermal low voltage electrical injury and in estimation of post injury intervals.

Human Lactate Dehydrogenase A (LDHA) Interaktionspartner

  1. LDHA phosphorylation and activation provide pro-invasive, anti-anoikis and pro-metastatic advantages to cancer cells, suggesting that Y10 phosphorylation of LDHA may represent a promising therapeutic target and a prognostic marker for metastatic human cancers.

  2. miR (zeige MLXIP Antikörper)-30a-5p may function as a tumor suppressor in breast cancer through the inhibition of LDHA expression and glycolysis.

  3. Overexpression of LDHA can be a marker of poor prognosis in cholangiocarcinoma patients

  4. LDHA-associated lactic acid accumulation in melanomas inhibits tumor surveillance by T and natural killer cells.

  5. Data indicate that lactate dehydrogenase A (LDHA) is involved in the transcription of histone 2B gene.

  6. LDHA downregulation is involved in the apoptotic effect of diallyl trisulfide in triple-negative breast cancer.

  7. this study shows that low levels of LDH correlate to a better anti-CTLA-4 (zeige CTLA4 Antikörper) immunotherapy response and survival in advanced melanoma patients

  8. alternative isoforms of LDH in cancer cells produce lactic acid, when LDHA is silenced or inhibited

  9. Overexpression of PKM2 and LDH5 associates with key clinicopathological features and unfavourable prognosis in tongue squamous cell carcinoma.

  10. These results suggest LDH-A and/or lactate as common elements at the cross-road between cancer cell metabolism, tumor progression and inflammation

Mouse (Murine) Lactate Dehydrogenase A (LDHA) Interaktionspartner

  1. Hair follicle stem cells maintain a metabolic state that allows them to remain dormant and yet quickly respond to appropriate proliferative stimuli mediated by LDH-A signaling.

  2. Results revealed that beta-arrestin-1 (zeige ARRB1 Antikörper) regulates lactate metabolism to contribute to beta2-adrenergic receptor (zeige ADRB2 Antikörper) functions in improved memory formation.

  3. The authors identified lactate dehydrogenase (LDH) as a new functional target of AMPKalpha1.

  4. LDHA-associated lactic acid accumulation in melanomas inhibits tumor surveillance by T and natural killer cells.

  5. lactate dehydrogenase A (LDHA) is induced in activated T cells to support aerobic glycolysis but promotes IFN-gamma (zeige IFNG Antikörper) expression independently of its 3'UTR (zeige UTS2R Antikörper).

  6. LDHA is a direct target of miR (zeige MLXIP Antikörper)-34a in regulating glucose metabolism and tumor growth in breast cancer.

  7. Findings suggest that RANKL protein-induced lactate dehydrogenase (LDH) activation stimulates glycolytic and mitochondrial respiratory metabolism via transcription factor NFATc1 signaling.

  8. We propose a profibrotic feed forward loop, in which radiation induces LDHA expression and lactate production, which can lead to further activation of TGF-beta (zeige TGFB1 Antikörper) to drive the fibrotic process.

  9. High LDH-A expression is associated with metastases in breast tumors.

  10. PGC-1alpha (zeige PPARGC1A Antikörper) reduces the expression of LDH A and one of its regulators, the transcription factor myelocytomatosis oncogene (zeige MYC Antikörper).

Pig (Porcine) Lactate Dehydrogenase A (LDHA) Interaktionspartner

  1. These findings indicated that heat shock (HS)-induced autophagy regulates lactate secretion by inhibiting apoptosis and increasing mRNA transcript and protein levels of SLC2A3 (zeige SLC2A3 Antikörper), LDHA, and SLC16A1 (zeige SLC16A1 Antikörper), which suggests that HS-induced autophagy may enhance lactate secretion by sertoli cells.

  2. The NADH-cofactor binding site of pig heart LDH is involved in the interaction with acidic phospholipids, in the pig skeletal muscle LDH, neither the cofactor binding site nor the subunit interfacing areas seem to be involved in the interaction.

  3. Both LDHA and COPB1 (zeige COPB1 Antikörper) were highly expressed in porcine skeletal muscle tissues, implying their potential regulatory function of muscle development.

Lactate Dehydrogenase A (LDHA) Antigen-Profil

Protein Überblick

The protein encoded by this gene catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. The protein is found predominantly in muscle tissue and belongs to the lactate dehydrogenase family. Mutations in this gene have been linked to exertional myoglobinuria. Multiple transcript variants encoding different isoforms have been found for this gene. The human genome contains several non-transcribed pseudogenes of this gene.

Genbezeichner und Symbole assoziert mit LDHA

  • lactate dehydrogenase A (ldha) Antikörper
  • lactate dehydrogenase A L homeolog (ldha.L) Antikörper
  • lactate dehydrogenase A (LDHA) Antikörper
  • lactate dehydrogenase A pseudogene (LOC784938) Antikörper
  • L-lactate dehydrogenase A chain (LOC100713875) Antikörper
  • lactate dehydrogenase A (Ldha) Antikörper
  • L-lactate dehydrogenase A chain pseudogene (LOC100357659) Antikörper
  • lactate dehydrogenase A4 (ldha) Antikörper
  • lactate dehydrogenase B L homeolog (ldhb.L) Antikörper
  • GSD11 Antikörper
  • l7R2 Antikörper
  • LDH-A Antikörper
  • ldh-h Antikörper
  • LDH-M Antikörper
  • Ldh1 Antikörper
  • ldha Antikörper
  • ldha-B Antikörper
  • ldha1 Antikörper
  • ldhab Antikörper
  • ldhbb Antikörper
  • LDHC Antikörper
  • Ldhm Antikörper
  • pig19 Antikörper
  • trg-5 Antikörper

Bezeichner auf Proteinebene für LDHA

lactate dehydrogenase A1 , L-lactate dehydrogenase A chain , LDH-A , LDH-M , LDH muscle subunit , lactate dehydrogenase C , lactate dehydrogenase-A , L-lactic acid dehydrogenase , lactate dehydrogenase A , upsilon-crystallin , M(A)-type lactate dehydrogenase , lactate dehydrogenase-M , cell proliferation-inducing gene 19 protein , lactate dehydrogenase M , proliferation-inducing gene 19 , renal carcinoma antigen NY-REN-59 , M-LDH , lactate dehydrogenase 1, A chain , lactate dehydrogenase A4 , lactate dehydrogenase A-like , ldha1

GENE ID SPEZIES
394758 Xenopus (Silurana) tropicalis
398121 Xenopus laevis
451063 Pan troglodytes
476882 Canis lupus familiaris
503513 Monodelphis domestica
784938 Bos taurus
791112 Ornithorhynchus anatinus
100057016 Equus caballus
100009107 Oryctolagus cuniculus
3939 Homo sapiens
100713875 Cavia porcellus
16828 Mus musculus
24533 Rattus norvegicus
407245 Sus scrofa
281274 Bos taurus
396221 Gallus gallus
100357659 Oryctolagus cuniculus
100173786 Pongo abelii
30496 Danio rerio
394355 Xenopus laevis
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