anti-LIM Domain Binding 3 (LDB3) Antikörper

LDB3 encodes a PDZ domain-containing protein. Zusätzlich bieten wir Ihnen LIM Domain Binding 3 Protein Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
LDB3 11155 O75112
LDB3 24131 Q9JKS4
LDB3 498587  
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Top anti-LIM Domain Binding 3 Protein Antikörper auf antikoerper-online.de

Showing 10 out of 65 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Ziege Unkonjugiert IHC, ELISA, WB ABIN185471 (0.01 ug/ml) staining of human muscle lysate (35 ug protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
349,82 €
Details
Human Maus Unkonjugiert WB LDB3 monoclonal antibody (M06A), clone 3C8 Western Blot analysis of LDB3 expression in A-431. Detection limit for recombinant GST tagged LDB3 is approximately 0.03 ng/mL as a capture antibody. 200 μL Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
Details
Human Ziege Unkonjugiert IHC (p), IHC, ELISA, WB ABIN250866 (0.01?g/ml) staining of Human Muscle lysate (35?g protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Western Blot: LDB3 Antibody [ABIN250866] - (0.1ug/ml) staining of Human Skeletal Muscle lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 2 bis 4 Tage
311,00 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
288,68 €
Details
Human Kaninchen Unkonjugiert WB Western Blot: LDB3 Antibody [NBP1-54998] - Titration: 0.625ug/ml Positive Control: Human heart. 100 μL Anmelden zum Anzeigen 3 bis 6 Tage
311,00 €
Details
Human Maus Unkonjugiert WB Western blot analysis of LDB3 over-expressed 293 cell line, cotransfected with LDB3 Validated Chimera RNAi used as specificity and loading control. Western Blot analysis of LDB3 expression in transfected 293T cell line by LDB3 monoclonal antibody (M06), clone 3C8. Lane 1: LDB3 transfected lysate(31 KDa). Lane 2: Non-transfected lysate. 100 μg Anmelden zum Anzeigen 12 bis 16 Tage
454,76 €
Details
Hund Ziege Unkonjugiert WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
357,50 €
Details
Human Maus Unkonjugiert IF, RNAi, ELISA, WB LDB3 monoclonal antibody (M06), clone 3C8 Western Blot analysis of LDB3 expression in A-431 . Western blot analysis of LDB3 over-expressed 293 cell line, cotransfected with LDB3 Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with LDB3 monoclonal antibody (M06), clone 3C8. GAPDH ( 36.1 kDa ) used as specificity and loading control. 100 μg Anmelden zum Anzeigen 7 bis 8 Tage
369,60 €
Details
Human Kaninchen Unkonjugiert WB LDB3 Antibody (Center)  western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the LDB3 antibody detected the LDB3 protein (arrow). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Ziege Unkonjugiert IHC (p), ELISA, WB Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
501,70 €
Details

LDB3 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Rat (Rattus) ,
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Am meisten referenzierte anti-LIM Domain Binding 3 Protein Antikörper

  1. Human Monoclonal LIM Domain Binding 3 Protein Primary Antibody für WB - ABIN4948229 : Zimmerman, Cox, Lakdawala, Cirino, Mancini-DiNardo, Clark, Leon, Duffy, White, Baxter, Alaamery, Farwell, Weiss, Seidman, Seidman, Ho, Rehm, Funke: A novel custom resequencing array for dilated cardiomyopathy. in Genetics in medicine : official journal of the American College of Medical Genetics 2010 (PubMed)
    Zeige alle 5 Referenzen für 4948229

  2. Human Monoclonal LIM Domain Binding 3 Protein Primary Antibody für WB - ABIN393692 : Rampersaud, Kinnamon, Hamilton, Khuri, Hershberger, Martin: Common susceptibility variants examined for association with dilated cardiomyopathy. in Annals of human genetics 2010 (PubMed)
    Zeige alle 5 Referenzen für 393692

  3. Human Polyclonal LIM Domain Binding 3 Protein Primary Antibody für IHC (p), IHC - ABIN250866 : Huang, Zhou, Liang, Hollander, Sheikh, Li, Greaser, Shelton, Evans, Chen: Characterization and in vivo functional analysis of splice variants of cypher. in The Journal of biological chemistry 2003 (PubMed)
    Zeige alle 4 Referenzen für 250866

  4. Human Monoclonal LIM Domain Binding 3 Protein Primary Antibody für IF, RNAi - ABIN524582 : Arimura, Inagaki, Hayashi, Shichi, Sato, Hinohara, Vatta, Towbin, Chikamori, Yamashina, Kimura: Impaired binding of ZASP/Cypher with phosphoglucomutase 1 is associated with dilated cardiomyopathy. in Cardiovascular research 2009 (PubMed)
    Zeige alle 2 Referenzen für 524582

  5. Human Polyclonal LIM Domain Binding 3 Protein Primary Antibody für WB - ABIN4229314 : Methawasin, Hutchinson, Lee, Smith, Saripalli, Hidalgo, Ottenheijm, Granzier: Experimentally increasing titin compliance in a novel mouse model attenuates the Frank-Starling mechanism but has a beneficial effect on diastole. in Circulation 2014 (PubMed)

  6. Human Polyclonal LIM Domain Binding 3 Protein Primary Antibody für IHC, ELISA - ABIN185471 : Selcen, Engel: Mutations in ZASP define a novel form of muscular dystrophy in humans. in Annals of neurology 2005 (PubMed)

Weitere Antikörper gegen LIM Domain Binding 3 Protein Interaktionspartner

Human LIM Domain Binding 3 (LDB3) Interaktionspartner

  1. this is the first family with Arrhythmogenic right ventricular cardiomyopathy where a mutation in LDB3 is associated with Arrhythmogenic right ventricular cardiomyopathy

  2. Study identified abnormal inclusion of LDB3 exon 11 specific to myotonic dystrophy type at the RNA and protein level; inclusion changed the affinity of LDB3 for PKC, indicating that exon 11 may contribute to the activation of PKC in DM1

  3. results show that MFM-associated ZASP mutations in the actin-binding domain have deleterious effects on the core structure of the Z-discs in skeletal muscle.

  4. Z-band alternatively spliced PDZ motif protein (ZASP) is the major O-linked beta-N-acetylglucosamine-substituted protein in human heart myofibrils

  5. This results of this indicted that One patient harbored the missense mutation c.1719G>A (p.V566M) in the ZASP gene.

  6. ZASP1 can form protein complex with telethonin/T-Cap (zeige TCAP Antikörper) and Na(v)1.5. The left ventricular noncompaction-specific ZASP1 mutation can cause loss of function of Na(v)1.5, without significant alteration of the cytoskeletal protein (zeige ACTN1 Antikörper) complex.

  7. TNNT3 and LDB3 showed abnormal splicing and appeared more pronounced in myotonic dystrophies type 2 relative to myotonic dystrophies type 1.

  8. the D626N mutation of Cypher/ZASP increases the affinity of the LIM (zeige PDLIM5 Antikörper) domain for protein kinase C (zeige PKC Antikörper), which may be related to pathogenesis of dilated cardiomyopathy

  9. ZASP/Cypher internal fragments containing either ZM exon 4 or 6 co-localized with alpha-actinin (zeige ACTN1 Antikörper) in cultured myoblasts and nonmuscle cells.

  10. ZASP/Cypher anchors PGM1 (zeige PGM1 Antikörper) to Z-disc under conditions of stress. The impaired binding of PGM1 (zeige PGM1 Antikörper) to ZASP/Cypher might be involved in the pathogenesis of dilated cardiomyopathy.

Mouse (Murine) LIM Domain Binding 3 (LDB3) Interaktionspartner

  1. Cypher and ENH (zeige PDLIM5 Antikörper) redundantly play an essential role in sustaining Z-line structure from the earliest stages of cardiac function, and are redundantly required to maintain normal embryonic heart function and embryonic viability.

  2. results show that MFM-associated ZASP mutations in the actin-binding domain have deleterious effects on the core structure of the Z-discs in skeletal muscle.

  3. Results indicte that Cypher/ZASP interacted with the regulatory subunit RIIalpha of PKA.

  4. Data demonstrated that the Z-disk proteins, ZASP, titin (zeige TTN Antikörper) and vinculin (zeige VCL Antikörper) preferentially bind to alpha-actinin-2 (zeige ACTN2 Antikörper).

  5. Deletion of long but not short Cypher isoforms leads to late-onset dilated cardiomyopathy.

  6. mutations of a structural/cytoskeletal protein (zeige ADD3 Antikörper), such as ZASP, lead to cardiac functional and electric abnormalities.

  7. Cypher isoforms are developmentally regulated in both skeletal and cardiac muscle

  8. Cypher plays a pivotal role in adult cardiac structure and function through protein-protein interactions with other Z-line proteins.

LIM Domain Binding 3 Protein (LDB3) Antigen-Profil

Protein Überblick

This gene encodes a PDZ domain-containing protein. PDZ motifs are modular protein-protein interaction domains consisting of 80-120 amino acid residues. PDZ domain-containing proteins interact with each other in cytoskeletal assembly or with other proteins involved in targeting and clustering of membrane proteins. The protein encoded by this gene interacts with alpha-actinin-2 through its N-terminal PDZ domain and with protein kinase C via its C-terminal LIM domains. The LIM domain is a cysteine-rich motif defined by 50-60 amino acids containing two zinc-binding modules. This protein also interacts with all three members of the myozenin family. Mutations in this gene have been associated with myofibrillar myopathy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been identified\; all isoforms have N-terminal PDZ domains while only longer isoforms (1, 2 and 5) have C-terminal LIM domains.

Genbezeichner und Symbole assoziert mit LDB3

  • LIM domain binding 3b (ldb3b) Antikörper
  • LIM domain binding 3 (ldb3) Antikörper
  • LIM domain binding 3 (LDB3) Antikörper
  • LIM domain binding 3 (LOC100348927) Antikörper
  • LIM domain binding 3 (Ldb3) Antikörper
  • AW742271 Antikörper
  • CMD1C Antikörper
  • CYPHER Antikörper
  • LDB3 Antikörper
  • ldb3l Antikörper
  • LDB3Z1 Antikörper
  • LDB3Z4 Antikörper
  • LVNC3 Antikörper
  • MFM4 Antikörper
  • MGC52706 Antikörper
  • MGC75668 Antikörper
  • ORACLE Antikörper
  • PDLIM6 Antikörper
  • RGD1564875 Antikörper
  • wu:fi31d08 Antikörper
  • ZASP Antikörper
  • zgc:55814 Antikörper

Bezeichner auf Proteinebene für LDB3

LIM domain binding 3 , LIM domain binding 3 like , LIM domain-binding protein 3 , PDZ and LIM domain 6 , Z-band alternatively spliced PDZ-motif protein , protein cypher , PDZ-LIM domain protein , cypher , oracle protein , protein oracle

GENE ID SPEZIES
334100 Danio rerio
379929 Xenopus laevis
394699 Xenopus (Silurana) tropicalis
697140 Macaca mulatta
100348927 Oryctolagus cuniculus
100582910 Nomascus leucogenys
11155 Homo sapiens
536781 Bos taurus
24131 Mus musculus
498587 Rattus norvegicus
479269 Canis lupus familiaris
100151883 Sus scrofa
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