anti-Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) Antikörper

KCNIP3 encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Zusätzlich bieten wir Ihnen Kv Channel Interacting Protein 3, Calsenilin Proteine (14) und Kv Channel Interacting Protein 3, Calsenilin Kits (10) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
KCNIP3 30818 Q9Y2W7
KCNIP3 56461 Q9QXT8
KCNIP3 65199 Q9JM47
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Top anti-Kv Channel Interacting Protein 3, Calsenilin Antikörper auf antikoerper-online.de

Showing 10 out of 146 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-CSEN Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>Jurkat cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IF, IHC (p), WB Western blot analysis of KChIP3 Antibody (N-term M1) (ABIN388402) in mouse heart tissue lysates (35 µg/lane). KChIP3(arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IF, IHC, ELISA, WB Western blot analysis of extracts from K562 cells treated with forskolin 40nM 30' and 293 cells treated with PMA 125ng/ml 30', using Calsenilin/KCNIP3 (Phospho-Ser63) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain, using Calsenilin/KCNIP3 (Phospho-Ser63) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IF, IHC, ELISA, WB Western blot analysis of extracts from MCF-7/Jurkat/A549 cells, using Calsenilin/KCNIP3 (Ab-63) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Calsenilin/KCNIP3 (Ab-63) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Rind (Kuh) Ziege Unkonjugiert EIA, WB <div class= 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Rind (Kuh) Ziege Unkonjugiert EIA, WB <div class= 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Ziege Unkonjugiert ELISA, WB Western Blot: Calsenilin Antibody [NBP2-26112] - HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human KCNIP3 with C-terminal MYC tag probed with EB10526 (1ug/ml) in Lane A and probed with anti-MYC Tag (1/1000) in lane C. Mock-transfected HEK293 probed with EB10526 (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$408.19
Details
Human Ziege Unkonjugiert ELISA, WB Western Blot: Calsenilin Antibody [NBP2-26111] - HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human KCNIP3 with C-terminal MYC tag probed with EB10525 (1ug/ml) in Lane A and probed with anti-MYC Tag (1/1000) in lane C. Mock-transfected HEK293 probed with EB10525 (1mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$408.19
Details

KCNIP3 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-Kv Channel Interacting Protein 3, Calsenilin Antikörper

  1. Mammalian Monoclonal KCNIP3 Primary Antibody für ISt, IHC - ABIN1304731 : Menegola, Trimmer: Unanticipated region- and cell-specific downregulation of individual KChIP auxiliary subunit isotypes in Kv4.2 knock-out mouse brain. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2006 (PubMed)
    Show all 16 Pubmed References

  2. Human Polyclonal KCNIP3 Primary Antibody für ELISA, WB - ABIN4287520 : Rivas, Mellström, Torres, Cali, Ferrara, Terracciano, Zannini, Morreale de Escobar, Naranjo: The DREAM protein is associated with thyroid enlargement and nodular development. in Molecular endocrinology (Baltimore, Md.) 2009 (PubMed)

  3. Cow (Bovine) Polyclonal KCNIP3 Primary Antibody für IHC, WB - ABIN2777506 : Zaidi, Thomson, Choi, Buxbaum, Wasco: Intracellular calcium modulates the nuclear translocation of calsenilin. in Journal of neurochemistry 2004 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen Kv Channel Interacting Protein 3, Calsenilin Interaktionspartner

Human Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) Interaktionspartner

  1. This study shows the application of hydrogen-deuterium exchange mass spectrometry and site-directed mutagenesis to investigate the Ca(2 (zeige CA2 Antikörper)+) binding properties and the subsequent conformational changes of full-length DREAM. EF-hands undergo large conformation changes upon calcium binding even though the EF-1 (zeige EEF1D Antikörper) hand is not capable of binding to Ca(2 (zeige CA2 Antikörper)+).

  2. Our approach yields high confidence ranked target gene maps for TP53 (zeige TP53 Antikörper), DREAM, MMB-FOXM1 (zeige FOXM1 Antikörper) and RB-E2F (zeige E2F1 Antikörper) and enables prediction and distinction of CC regulation. A web-based atlas at www.targetgenereg.org enables assessing the regulation of any human gene of interest.

  3. downregulation of these genes through the p53 (zeige TP53 Antikörper)-p21 (zeige CDKN1A Antikörper)-DREAM-CDE/CHR pathway appears to be a principal mechanism for G2/M cell cycle arrest by p53 (zeige TP53 Antikörper).

  4. Our results support the hypothesis that KChIPs enhances Kv4.2 (zeige KCND2 Antikörper) functional expression by a 1 : 1 suppression of the N-terminal FERN domain and by producing additional positive regulatory effects on functional channel expression.

  5. GCM1 (zeige GCM1 Antikörper)-directed villous trophoblast differentiation is repressed by DREAM

  6. p53 (zeige TP53 Antikörper) can repress transcription of cell cycle genes through a p21(WAF1/CIP1 (zeige CDKN1A Antikörper))-dependent switch from MMB to DREAM protein complex binding at CHR promoter elements.

  7. The potassium channel interacting protein 3 (DREAM/KChIP3) heterodimerizes with and regulates calmodulin (zeige CALM1 PLURAL_@27095@) function.

  8. expression of calsenilin leads to a disruption of presenilin 1 (zeige PSEN1 Antikörper)/gamma-secretase-mediated epsilon-cleavage of N-cadherin (zeige CDH2 Antikörper), which results in the significant accumulation of N-cadherin (zeige CDH2 Antikörper) C-terminal fragment 1

  9. The results show that continued human papillomavirus 16 E6/E7 expression is necessary in cervical cancer cells to prevent cell-cycle arrest by a repressive p130 (zeige RBL2 Antikörper)-DREAM complex.

  10. These findings suggest that calsenilin degradation is primarily mediated by the UPP (zeige UPP1 Antikörper) and that impairment in the UPP (zeige UPP1 Antikörper) may contribute to the involvement of calsenilin in disease-associated neurodegeneration.

Mouse (Murine) Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) Interaktionspartner

  1. Genome-wide analysis of trigeminal neurons in daDREAM transgenic mice identified cathepsin L (zeige CTSL1 Antikörper) and the monoglyceride lipase (zeige MGLL Antikörper) as two new DREAM transcriptional targets related to pain.

  2. association of PS1 (zeige PSEN1 Antikörper) carboxyl peptide (residues 445-467, HL9 (zeige DDC Antikörper)) with DREAM is calcium dependent and stabilized by a cluster of three aromatic residues: F462 and F465 from PS1 (zeige PSEN1 Antikörper) and F252 from DREAM.

  3. The association of calcium-bound calmodulin (CaM) with DREAM is mediated by a short amphipathic amino acid sequence located between residues 29 and 44 on DREAM.

  4. The protein DREAM decreases development of L-DOPA-induced dyskinesia in mice and reduces L-DOPA-induced expression of FosB (zeige FOSB Antikörper), phosphoacetylated histone H3 (zeige HIST3H3 Antikörper), and dynorphin-B in the striatum

  5. NS5806 directly interacts with KChIP3 and modulates the interactions between this calcium-binding protein (zeige GUCA1B Antikörper) and the T1 domain of the Kv4.3 (zeige KCND3 Antikörper) channels through reorientation of helix 10 on KChIP3

  6. studies define the critical opposing functions of DREAM and USF1 (zeige USF1 Antikörper) in inhibiting and inducing A20 (zeige TNFAIP3 Antikörper) expression

  7. GCM1 (zeige GCM1 Antikörper)-directed villous trophoblast differentiation is repressed by DREAM

  8. Expression of DREAM in neuroblastoma (zeige ARHGEF16 Antikörper) cells enhances cisplatin mediated caspase-3 (zeige CASP3 Antikörper) activity.

  9. Restoring CANT1 (zeige CANT1 Antikörper) levels in neuroblastoma (zeige ARHGEF16 Antikörper) clones recovered the phenotype, thus confirming a key role of CANT1 (zeige CANT1 Antikörper), and of the regulation of its gene by DREAM, in the control of protein synthesis and degradation

  10. In cardiomyocytes, [Ca2 (zeige CA2 Antikörper)+]i-activated calmodulin kinase II (CaMKII (zeige CAMK2 Antikörper)) activates downstreamregulatory element (DRE (zeige SUFUH Antikörper)) binding transcription factor DREAM, which consequently suppresses the expression of L-type calcium channel 1C-subunit gene (Cacna1c (zeige CACNA1C Antikörper)).

Zebrafish Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) Interaktionspartner

  1. zebrafish calsenilin is involved in endocrine cell differentiation and morphogenesis within the pancreas

Kv Channel Interacting Protein 3, Calsenilin (KCNIP3) Antigen-Profil

Protein Überblick

This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins, which belong to the recoverin branch of the EF-hand superfamily. Members of this family are small calcium binding proteins containing EF-hand-like domains. They are integral subunit components of native Kv4 channel complexes that may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. The encoded protein also functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. Alternatively spliced transcript variants encoding different isoforms have been described.

Genbezeichner und Symbole assoziert mit KCNIP3

  • calsenilin (AaeL_AAEL007002) Antikörper
  • calsenilin (CpipJ_CPIJ002549) Antikörper
  • calsenilin (Tsp_05009) Antikörper
  • Kv channel interacting protein 3, calsenilin (KCNIP3) Antikörper
  • Kv channel interacting protein 3, calsenilin (kcnip3) Antikörper
  • calsenilin-like (LOC100856050) Antikörper
  • Kv channel interacting protein 3, calsenilin (Kcnip3) Antikörper
  • Kv channel interacting protein 3b, calsenilin (kcnip3b) Antikörper
  • 4933407H12Rik Antikörper
  • AI413860 Antikörper
  • csen Antikörper
  • Dream Antikörper
  • im:7145308 Antikörper
  • KChIP3 Antikörper
  • kcnip3 Antikörper
  • R74849 Antikörper
  • rKChIP3 Antikörper
  • zgc:73306 Antikörper

Bezeichner auf Proteinebene für KCNIP3

calsenilin , Kv channel interacting protein 3, calsenilin , A-type potassium channel modulatory protein 3 , DRE-antagonist modulator , calsenilin, presenilin-binding protein, EF hand transcription factor , kv channel-interacting protein 3 , potassium channel interacting protein 3 , calsenilin, presenilin binding protein, EF hand transcription factor , A-type potassium channel modulating protein 3 , KChIP3 , calsenilin presenilin-binding protein EF hand transcription factor , calsenilin, presenilin-binding protein, EF hand transcription fa , downstream regulatory element-antagonist modulator

GENE ID SPEZIES
5568664 Aedes aegypti
6033823 Culex quinquefasciatus
10912880 Trichinella spiralis
459401 Pan troglodytes
704307 Macaca mulatta
100135241 Xenopus (Silurana) tropicalis
100856050 Canis lupus familiaris
30818 Homo sapiens
56461 Mus musculus
65199 Rattus norvegicus
513316 Bos taurus
609135 Canis lupus familiaris
393755 Danio rerio
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