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KLF6 encodes a member of the Kruppel-like family of transcription factors. Zusätzlich bieten wir Ihnen KLF6 Proteine (12) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 48 products:
Human Monoclonal KLF6 Primary Antibody für IHC, WB - ABIN2668584
Narla, DiFeo, Yao, Banno, Hod, Reeves, Qiao, Camacho-Vanegas, Levine, Kirschenbaum, Chan, Friedman, Martignetti: Targeted inhibition of the KLF6 splice variant, KLF6 SV1, suppresses prostate cancer cell growth and spread. in Cancer research 2005
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Human Polyclonal KLF6 Primary Antibody für FACS, IF - ABIN390515
Sangodkar, Shi, DiFeo, Schwartz, Bromberg, Choudhri, McClinch, Hatami, Scheer, Kremer-Tal, Martignetti, Hui, Leung, Friedman, Narla: Functional role of the KLF6 tumour suppressor gene in gastric cancer. in European journal of cancer (Oxford, England : 1990) 2009
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Human Monoclonal KLF6 Primary Antibody für ELISA, WB - ABIN560438
Lin, Jiang, Chuu: Caffeic acid phenethyl ester causes p21 induction, Akt signaling reduction, and growth inhibition in PC-3 human prostate cancer cells. in PLoS ONE 2012
Our study provides new evidence that interaction of KLF6 and Sp1 regulates basigin-2 expression in hepatocellular carcinoma
MIIP (zeige MIIP Antikörper) and PAK1 (zeige PAK1 Antikörper) bind each other and a C-terminal polyproline domain of MIIP (zeige MIIP Antikörper) is required for PAK1 (zeige PAK1 Antikörper) binding. Ectopically expressed MIIP (zeige MIIP Antikörper) consistently competed with Rac1-GTP (zeige AK3 Antikörper) for binding with the PAK1 (zeige PAK1 Antikörper) p21 (zeige CDKN1A Antikörper)-binding domain in endometrial cancer cells.
hypoxia induced an early and transient increase in KLF6 protein levels in HTR8/SVneo extravillous cytotrophoblast cells and in placental explants. Reoxygenation returned KLF6 protein to basal levels. Moreover, hypoxia-induced up-regulation of KLF6 expression was dependent on HIF-1alpha (zeige HIF1A Antikörper). These results indicate that KLF6 may mediate some of the effects of hypoxia in placental development.
The study highlights the central role of myeloid KLF6 in promoting intestinal inflammation.
study identifies a new mechanism by which KLF6 regulates NF-kappaB (zeige NFKB1 Antikörper) signaling, and how this mechanism is circumvented in glioblastoma through KLF6 loss.
our results established the significance of activating the KLF6-E2F1 (zeige E2F1 Antikörper) axis in aggressive primary metastatic clear cell renal cell carcinoma (zeige MOK Antikörper)
KLF6 overexpression suppressed the xenograft tumor growth.
KLF6 and KLF15 are targeted and suppressed in breast cancer cells by miR (zeige MLXIP Antikörper)-4262.
KLF6 acts as a tumor suppressor in CMM cells and miR (zeige MLXIP Antikörper)-4262 promotes the proliferation of CMM cells through KLF6-mediated EGFR (zeige EGFR Antikörper) inactivation and p21 (zeige CDKN1A Antikörper) upregulation.
These results suggest that KLF6 regulates MMP14 (zeige MMP14 Antikörper) transcription and is a critical player of the gene expression network triggered during endothelial repair.
KLF6-mediated activation of the human INSL3 (zeige INSL3 Antikörper) promoter required an intact KLF element as well as Leydig/Sertoli-enriched factors. KLF6 transcriptionally cooperates with NUR77 (zeige NR4A1 Antikörper) and SF1 (zeige SF1 Antikörper). our results identify KLF6 as a regulator of human INSL3 (zeige INSL3 Antikörper) transcription.
we identified novel transcriptional targets of KLF6 in HCC cells including VAV3, a known activator of the RAC1 small GTPase. Indeed, RAC1 activity is increased in KLF6-knockdown cells in a VAV3-dependent manner, and knockdown of either RAC1 or VAV3 impairs HCC cell migration. Together, our data demonstrate a novel function for KLF6 in constraining HCC dissemination through the regulation of a VAV3-RAC1 signaling axis.
Klf6 as required for developmental central nervous system myelination.Klf6 promotes oligodendrocyte differentiation and viability.
observations reveal that KLF6 repress BCL6 (zeige BCL6 Antikörper) to enhance macrophage inflammatory gene expression and function.
present studies on the cardiac function of KLF6 show a new mechanism whereby cardiomyocytes regulate cardiac fibrosis through transcriptional control of the extracellular matrix factor thrombospondin 4 (zeige THBS4 Antikörper)
downregulates expression and secretion of granulocyte macrophage colony-stimulating factor (zeige CSF2 Antikörper)
KLF6-dependent regulation of the cytochrome c (zeige CYCS Antikörper) oxidase assembly gene is critical for maintaining mitochondrial function and preventing podocyte apoptosis.
findings provide novel evidence highlighting KLF6 function in response to malignant transformation, suggesting the relevance of KLF6 in controlling cell proliferation and hindering tumorigenesis
KLF6 is required for optimal LPS (zeige TLR4 Antikörper)-induced pro-inflammatory gene expression, acting cooperatively with NF-kappaB (zeige NFKB1 Antikörper)
Klf6a promotes hematopoietic stem and progenitor cell maintenance through Ccl25b-Ccr7 (zeige CCR7 Antikörper) chemokine (zeige CCL1 Antikörper) signaling.
In the spinal cord, klf7 (zeige KLF7 Antikörper)- and klf6a-expressing cells are found in both the dorsal and ventral horns. Numerous sensory structures (e.g. auditory, lateral line, olfactory and visual) and several motor nuclei (e.g. oculomotor, trigeminal, and vagal motor nuclei) contain klf7 (zeige KLF7 Antikörper)- and/or klf6a-expressing cells
copeb/Klf6 is essential for the development of endoderm-derived organs
This gene encodes a member of the Kruppel-like family of transcription factors. The zinc finger protein is a transcriptional activator, and functions as a tumor suppressor. Multiple transcript variants encoding different isoforms have been found for this gene, some of which are implicated in carcinogenesis.
Kruppel-like factor 6
, core promoter element binding protein
, Krueppel-like factor 6
, krueppel-like factor 6
, B-cell-derived protein 1
, GC-rich binding factor
, GC-rich sites-binding factor GBF
, Kruppel-like zinc finger protein Zf9
, core promoter element-binding protein
, proto-oncogene BCD1
, protooncogene B-cell derived 1
, suppression of tumorigenicity 12 (prostate)
, suppressor of tumorigenicity 12 protein
, transcription factor Zf9
, immediate early response, erythropoietin 1