anti-Ketohexokinase (KHK) Antikörper

KHK encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. Zusätzlich bieten wir Ihnen Ketohexokinase Proteine (17) und Ketohexokinase Kits (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
KHK 16548 P97328
KHK 25659 Q02974
KHK 3795 P50053
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Top anti-Ketohexokinase Antikörper auf antikoerper-online.de

Showing 10 out of 121 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert WB The anti-KHK Pab (ABIN391088) is used in Western blot to detect KHK in mouse liver tissue lysate (Lane 1) and 293 cell lysate (Lane 2). Western blot analysis of KHK (arrow) using rabbit polyclonal Ketohexokinase (KHK) Antibody (N-term) (ABIN391088). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the KHK gene (Lane 2) (Origene Technologies). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert WB The anti-KHK Pab (ABIN391089) is used in Western blot to detect KHK in mouse kidney tissue lysate. Western blot analysis of KHK (arrow) using rabbit polyclonal Ketohexokinase (KHK) Antibody (C-term) (ABIN391089). 293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the KHK gene (Lane 2) (Origene Technologies). 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert EIA, WB The anti-KHK Pab is used in Western blot to detect KHK in mouse liver tissue lysate (Lane 1) and 293 cell lysate (Lane 2). 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 3 bis 4 Tage
349,82 €
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: Ketohexokinase Antibody [NBP1-85790] - Staining of human cell line U-2 OS shows positivity in cytoplasm. Immunohistochemistry-Paraffin: Ketohexokinase Antibody [NBP1-85790] - Staining of human kidney shows strong nuclear and cytoplasmic positivity in cells in tubules. 0.1 mL Anmelden zum Anzeigen 5 bis 8 Tage
335,00 €
Details
Human Kaninchen Unkonjugiert EIA, WB The anti-KHK Pab is used in Western blot to detect KHK in mouse kidney tissue lysate 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (36.78 KDa) . 50 μL Anmelden zum Anzeigen 7 bis 8 Tage
241,60 €
Details
Human Maus Unkonjugiert FACS, IF, WB 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
583,17 €
Details

KHK Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Ketohexokinase Antikörper

  1. Human Polyclonal KHK Primary Antibody für ELISA, WB - ABIN561590 : DAmour, Agulnick, Eliazer, Kelly, Kroon, Baetge: Efficient differentiation of human embryonic stem cells to definitive endoderm. in Nature biotechnology 2005 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal KHK Primary Antibody für IHC, IHC (p) - ABIN4328612 : Ishimoto, Lanaspa, Le, Garcia, Diggle, Maclean, Jackman, Asipu, Roncal-Jimenez, Kosugi, Rivard, Maruyama, Rodriguez-Iturbe, Sánchez-Lozada, Bonthron, Sautin, Johnson: Opposing effects of fructokinase C and A isoforms on fructose-induced metabolic syndrome in mice. in Proceedings of the National Academy of Sciences of the United States of America 2012 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal KHK Primary Antibody für WB - ABIN391089 : Springer, Lindbloom-Hawley, Schermerhorn: Tissue expression of ketohexokinase in cats. in Research in veterinary science 2009 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal KHK Primary Antibody für ELISA, WB - ABIN561589 : Levi, Cheng, Gheysens, Patel, Chan, Wang, Namavari, Gambhir: Fluorescent fructose derivatives for imaging breast cancer cells. in Bioconjugate chemistry 2007 (PubMed)

  5. Cow (Bovine) Polyclonal KHK Primary Antibody für WB - ABIN2776884 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007 (PubMed)

Weitere Antikörper gegen Ketohexokinase Interaktionspartner

Mouse (Murine) Ketohexokinase (KHK) Interaktionspartner

  1. This studies provided the first evidence that fructokinase modulates vasopressin (zeige AVP Antikörper) synthesis in the SON and secretion from the posterior pituitary into circulation.

  2. Fructokinase knockout mice were protected from renal injury both at baseline and after high salt intake (3 wk) compared with wild-type mice. This was associated with higher levels of active (phosphorylated serine 1177) endothelial nitric oxide synthase (zeige NOS3 Antikörper) in their kidneys.

  3. Feedforward upregulation of fructolytic and gluconeogenic enzymes specifically requires GLUT5 (zeige SLC2A5 Antikörper) and KHK and may proactively enhance the intestine's ability to process anticipated increases in dietary fructose concentrations.

  4. Significant levels of blood fructose are maintained independent of dietary fructose, KHK, and GLUT5 (zeige SLC2A5 Antikörper), probably by endogenous synthesis of fructose.

  5. myocardial hypoxia actuates fructose metabolism in human and mouse models of pathological cardiac hypertrophy through hypoxia-inducible factor 1alpha (HIF1alpha (zeige HIF1A Antikörper)) activation of SF3B1 (zeige SF3B1 Antikörper) and SF3B1 (zeige SF3B1 Antikörper)-mediated splice switching of KHK-A to KHK-C

  6. Fructokinase-knockout mice with delayed hydration were protected from renal injury. Thus, recurrent dehydration can induce renal injury via a fructokinase-dependent mechanism, likely from the generation of endogenous fructose via the polyol pathway.

  7. This study demonstrates that blocking KHK and redirecting fructose metabolism to alternative pathways is an effective way to prevent visceral obesity and insulin (zeige INS Antikörper) resistance induced by high fructose, a widespread component of Western diets.

  8. These studies identify fructokinase as a novel mediator of diabetic nephropathy and document a novel role for endogenous fructose production, or fructoneogenesis, in driving renal disease.

  9. High-fat and high-sucrose (western) diet induces steatohepatitis that is dependent on fructokinase.

  10. Fructose-induced metabolic syndrome is prevented in mice lacking both fructokinase B and A but is exacerbated in mice lacking fructokinase A.

Human Ketohexokinase (KHK) Interaktionspartner

  1. Angelica archangelica, Garcinia mangostana, Petroselinum crispum, and Scutellaria baicalensis were the top four botanical candidiates identified with inhibitory activity against ketohexokinase-C.

  2. compared with normal hepatocytes, hepatocellular carcinoma (HCC (zeige FAM126A Antikörper)) cells markedly reduce the rate of fructose metabolism and the level of reactive oxygen species, as a result of a c-Myc (zeige MYC Antikörper)-dependent and heterogeneous nuclear ribonucleoprotein (zeige PCBP2 Antikörper) (hnRNP (zeige HNRNPC Antikörper)) H1- and H2-mediated switch from expression of the high-activity fructokinase (KHK)-C to the low-activity KHK-A isoform.

  3. myocardial hypoxia actuates fructose metabolism in human and mouse models of pathological cardiac hypertrophy through hypoxia-inducible factor 1alpha (HIF1alpha (zeige HIF1A Antikörper)) activation of SF3B1 (zeige SF3B2 Antikörper) and SF3B1 (zeige SF3B2 Antikörper)-mediated splice switching of KHK-A to KHK-C

  4. These studies identify fructokinase as a novel mediator of diabetic nephropathy and document a novel role for endogenous fructose production, or fructoneogenesis, in driving renal disease.

  5. This study determined if single nucleotide polymorphisms in genes involved in fructose transport,SLC2A2 (zeige SLC2A2 Antikörper) and SLC2A5 (zeige SLC2A5 Antikörper) and metabolism, etohexokinase affect inter-individual variability in metabolic phenotypes.

  6. In human hepatocytes uric acid up-regulates KHK expression thus leading to the amplification of the lipogenic effects of fructose.

  7. ketohexokinase-A serves an unknown physiologic function that remains intact in essential fructosuria.

  8. The expression of ketohexokinase is diminished in human clear cell type of renal cell carcinoma (zeige MOK Antikörper)

  9. Ketohexokinase-dependent metabolism of fructose induces proinflammatory mediators in proximal tubular cells.

  10. The structure of the KHK-A ternary complex revealed an active site with fructose & the ATP analogue in positions ready for phosphorylation. The effects of the pathogenic mutations Gly40Arg & Ala43Thr have been modelled in the context of the KHK structure.

Ketohexokinase (KHK) Antigen-Profil

Protein Überblick

This gene encodes ketohexokinase that catalyzes conversion of fructose to fructose-1-phosphate. The product of this gene is the first enzyme with a specialized pathway that catabolizes dietary fructose. Alternatively spliced transcript variants encoding different isoforms have been identified.

Genbezeichner und Symbole assoziert mit anti-Ketohexokinase (KHK) Antikörper

  • ketohexokinase-like (LOC100055449) Antikörper
  • ketohexokinase (khk) Antikörper
  • ketohexokinase (KHK) Antikörper
  • ketohexokinase (Hhal_0921) Antikörper
  • ketohexokinase (AaeL_AAEL006316) Antikörper
  • Ketohexokinase (Nwat_0240) Antikörper
  • Ketohexokinase (khk) Antikörper
  • ketohexokinase (LOC100351729) Antikörper
  • ketohexokinase (Khk) Antikörper
  • ketohexokinase (fructokinase) (KHK) Antikörper
  • ketohexokinase-like (LOC100523241) Antikörper
  • KETHPRO Antikörper
  • khk Antikörper
  • wu:fj68h03 Antikörper
  • zgc:92219 Antikörper
  • zgc:92626 Antikörper

Bezeichner auf Proteinebene für anti-Ketohexokinase (KHK) Antikörper

ketohexokinase , Ketohexokinase , hepatic fructokinase

GENE ID SPEZIES
100055449 Equus caballus
436909 Danio rerio
698328 Macaca mulatta
4710193 Halorhodospira halophila SL1
5567860 Aedes aegypti
9391692 Nitrosococcus watsonii C-113
100306748 Salmo salar
100351729 Oryctolagus cuniculus
16548 Mus musculus
25659 Rattus norvegicus
3795 Homo sapiens
100170647 Canis lupus familiaris
614868 Bos taurus
100447147 Pongo abelii
100523241 Sus scrofa
Ausgewählte Anbieter für anti-Ketohexokinase (KHK) Antikörper
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