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The protein encoded by KRT19 is a member of the keratin family. Zusätzlich bieten wir Ihnen Keratin 19 Antikörper (940) und Keratin 19 Proteine (30) und viele weitere Produktgruppen zu diesem Protein an.
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Findings provide evidence that K19 expression is inducible in human hepatocellular carcinoma as a sign of tumor progression.
Urine levels of COL4A1 (zeige COL4A1 ELISA Kits), COL13A1 (zeige COL13A1 ELISA Kits), the combined values of COL4A1 (zeige COL4A1 ELISA Kits) and COL13A1 (zeige COL13A1 ELISA Kits) (COL4A1 (zeige COL4A1 ELISA Kits) + COL13A1 (zeige COL13A1 ELISA Kits)), and CYFRA21-1 were significantly elevated in urine from patients with BCa (zeige BLNK ELISA Kits) compared to the controls. A high urinary COL4A1 (zeige COL4A1 ELISA Kits) + COL13A1 (zeige COL13A1 ELISA Kits) was found to be an independent risk factor for intravesical recurrence.
CK19 and carcinoembryonic antigen (zeige CEACAM5 ELISA Kits) may be involved in lymph node metastasis and poor prognosis in patients with gastriccardia cancer
The study has confirmed the preservation of CK19 protein expression in breast cancer cells after neoadjuvant therapy. On the basis of these results, quantification-based methods such as the one-step nucleic acid amplification (OSNA) CK19 assay, could be an accurate tool with which to analyse the sentinel nodes, regardless of whether they had been obtained before or after treatment.
Serum CYFRA 21-1 level may be a predictive factor for patients with non-small cell lung cancers treated with EGFR (zeige EGFR ELISA Kits)-TKIs, regardless of EGFR (zeige EGFR ELISA Kits) mutation status.
Data suggest that keratin (K) 19 (K19) may be a drug target for the treatment of K19-positive hepatocellular carcinoma (HCC (zeige FAM126A ELISA Kits)).
Combination of the two tumor markers, CEA (zeige CEACAM5 ELISA Kits) and CYFRA21-1, is a predictive and prognostic marker of docetaxel monotherapy for previously treated NSCLC patients
Results suggest that positive expression of CK19 mRNA and TK1 (zeige TK1 ELISA Kits) protein is closely correlated with poor prognosis in advanced gastrointestinal cancer.
GPC3 (zeige GPC3 ELISA Kits) and KRT19 overexpression are associated with carcinogenesis, progression, and poor prognosis in patients with PDAC and a valuable biomarker for diagnosis of PDAC.
Data show that sixty one patients with a high cytokeratin 19 fragment (CYFRA 21-1) level had statistically shorter progression-free and overall survival than 39 patients with a normal CYFRA 21-1 level .
Demonstrate that K19 plays an important role in the ductular reaction that constitutes the basic regenerative response to chronic liver injury.
Branched desmin (zeige DES ELISA Kits)-deficient (DKO) myofibers show significantly faster rates of calcium ion (Ca2 (zeige CA2 ELISA Kits)+) clearance, with milder branching phenotype observed in DKO muscle suggesting that absence of keratin-19 corrects the defect created by absence of desmin (zeige DES ELISA Kits) alone.
the structural response of each genotype is distinct, suggesting multiple mechanisms by which desmin and keratin influence the biomechanical properties of myofibers
The expression of CK19 and EGFR (zeige EGFR ELISA Kits) in lymphatic metastasis of laryngeal carcinoma was higher than in controls.
Results suggest that keratin filaments containing K19- and desmin (zeige DES ELISA Kits)-based intermediate filaments can play independent, complementary, or antagonistic roles in the physiology and morphology of fast-twitch skeletal muscle.
a dual mechanism of how PDX-1 (zeige PDX1 ELISA Kits) negatively regulates Krt19 ductal specific gene expression
expression of nestin (zeige NES ELISA Kits) and cytokeratin 19 is a normal property of embryonic stem cells preceding differentiation into C-peptide/insulin (zeige INS ELISA Kits)-producing cells without any selection for nestin (zeige NES ELISA Kits)-positive phenotypes
loss of the keratin cytoskeleton causes defects in the trophoblast giant cell layer
transduction of PDX1 (zeige PDX1 ELISA Kits) in primary pancreatic ductal cells suppresses K19 expression, and short interfering RNA to PDX1 (zeige PDX1 ELISA Kits) in Min6 insulinoma (zeige RPS15 ELISA Kits) cells and results in the induction of normally undetectable K19
This is the first demonstration of a mammalian phenotype associated with a genetic perturbation of keratin 19.
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. Unlike its related family members, this smallest known acidic cytokeratin is not paired with a basic cytokeratin in epithelial cells. It is specifically expressed in the periderm, the transiently superficial layer that envelopes the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21.
40-kDa keratin intermediate filament
, cytokeratin 19
, keratin, type I cytoskeletal 19
, keratin, type I, 40-kd
, keratin complex 1, acidic, gene 19
, type I keratin KA19
, keratin 19
, Keratin, type I cytoskeletal 19
, keratin, type I cytoskeletal 19-like
, keratin 19, type I