Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B) ELISA Kits

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. Zusätzlich bieten wir Ihnen Isocitrate Dehydrogenase 3 (NAD+) beta Antikörper (79) und Isocitrate Dehydrogenase 3 (NAD+) beta Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Human IDH3B IDH3B 3420 O43837
Anti-Ratte IDH3B IDH3B 94173 Q68FX0
Anti-Maus IDH3B IDH3B 170718  
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Weitere ELISA Kits für Isocitrate Dehydrogenase 3 (NAD+) beta Interaktionspartner

Human Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B) Interaktionspartner

  1. Human NAD-dependent isocitrate dehydrogenase (IDH) is a heterotetrameric mitochondrial enzyme with 2alpha:1beta:1gamma subunit ratio subunits shich share 40-52% identity in amino acid sequence.

  2. IDPm (zeige IDH2 ELISA Kits) activity appears to be modulated through enzymatic glutathionylation and deglutathionylation during oxidative stress

  3. active sites of the human NAD-IDH are shared between alpha and gamma subunits and between alpha and beta subunits

  4. Asp192 is needed for optimal affinity of IDH (zeige IDH1 ELISA Kits) beta subunit (zeige POLG ELISA Kits) for nicotinamide-adenine dinucleotide (NAD) substrate, but is not critical for catalysis.

  5. Homozygous for loss-of-function mutations in IDH3B is associated with retinitis pigmentosa.

  6. The point mutations of isocitrate dehydrogenase (zeige IDH1 ELISA Kits) are essentially unique to gliomas.

Isocitrate Dehydrogenase 3 (NAD+) beta (IDH3B) Antigen-Profil

Beschreibung des Gens

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit. The protein encoded by this gene is the beta subunit of one isozyme of NAD(+)-dependent isocitrate dehydrogenase. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Genbezeichner und Symbole assoziert mit IDH3B

  • isocitrate dehydrogenase 3 (NAD(+)) beta (IDH3B) Antikörper
  • isocitrate dehydrogenase 3 (NAD+) beta (Idh3B) Antikörper
  • isocitrate dehydrogenase 3 (NAD+) beta (Idh3b) Antikörper
  • isocitrate dehydrogenase 3 (NAD+) beta (idh3b) Antikörper
  • isocitrate dehydrogenase 3 (NAD+) beta S homeolog (idh3b.S) Antikörper
  • isocitrate dehydrogenase 3 (NAD(+)) beta (Idh3b) Antikörper
  • C78231 Antikörper
  • H-IDHB Antikörper
  • IDH1 Antikörper
  • IDH3 Antikörper
  • MGC79028 Antikörper
  • RP46 Antikörper
  • zgc:86647 Antikörper

Bezeichner auf Proteinebene für IDH3B

NAD(+)-specific ICDH subunit beta , NAD+-specific ICDH , NAD+-specific isocitrate dehydrogenase b subunit , NAD+-specific isocitrate dehydrogenase beta , isocitrate dehydrogenase [NAD] subunit beta, mitochondrial , isocitrate dehydrogenase, NAD(+)-specific, mitochondrial, beta subunit , isocitric dehydrogenase subunit beta , N14A tumor-related protein , isocitrate dehydrogenase 3 beta , isocitrate dehydrogenase 3, beta subunit , isocitrate dehydrogenase 3 (NAD+) beta , NAD(+)-dependent isocitrate dehydrogenase subunit 3 , NAD(+)-isocitrate dehydrogenase subunit 1 , mitochondrial NAD+isocitrate dehydrogenase 3 beta variant 2 , isocitrate dehydrogenase [NAD] subunit beta, mitochondrial-like

GENE ID SPEZIES
3420 Homo sapiens
94173 Rattus norvegicus
170718 Mus musculus
415247 Danio rerio
426573 Gallus gallus
443821 Xenopus laevis
458048 Pan troglodytes
477177 Canis lupus familiaris
613338 Bos taurus
733641 Sus scrofa
100144949 Xenopus (Silurana) tropicalis
100172344 Pongo abelii
100403538 Callithrix jacchus
100717400 Cavia porcellus
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