Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) ELISA Kits

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. Zusätzlich bieten wir Ihnen IDH2 Antikörper (115) und IDH2 Proteine (20) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
IDH2 3418 P48735
IDH2 269951 P54071
IDH2 361596 P56574
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Top IDH2 ELISA Kits auf antikoerper-online.de

Showing 6 out of 14 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.061 ng/mL 0.156-10 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
875,63 €
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Human 0.098 ng/mL 0.312-20 ng/mL   96 Tests Anmelden zum Anzeigen 6 bis 8 Tage
679,90 €
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Maus
  96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
788,70 €
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Ratte
  96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
788,70 €
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Schwein
  96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
945,85 €
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Rind (Kuh)
  96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
945,85 €
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Weitere ELISA Kits für IDH2 Interaktionspartner

Pig (Porcine) Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) Interaktionspartner

  1. Tyr140 and Lys212 are required for the catalytic activity of porcine NADP-dependent isocitrate dehydrogenase (zeige IDH3B ELISA Kits)

  2. analysis of the coenzyme binding site in the porcine mitochondrial NADP-dependent isocitrate dehydrogenase (zeige IDH3B ELISA Kits)

  3. These results suggest that IDPm plays an important protective role in cadmium-induced apoptosis by maintaining cellular redox status and by protection of Grx (zeige GRX1 ELISA Kits) activity.

Arabidopsis thaliana Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) Interaktionspartner

  1. Leaf IDH activity reduced by 43% in mutant

Human Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) Interaktionspartner

  1. IDH (zeige IDH1 ELISA Kits) mutations define a distinct subtype of ICC, a malignancy that is largely refractory to current therapies. Our work demonstrates that IDHm ICC cells are hypersensitive to dasatinib and critically dependent on SRC (zeige SRC ELISA Kits) activity for survival and proliferation, pointing to new therapeutic strategies against these cancers.

  2. Mutations in the IDH1 (zeige IDH1 ELISA Kits) and IDH2 genes perturb the epigenome through cytosine methylation, histone post-translational modifications and transcription factors. [review]

  3. IDH2 mutation is associated with high-grade gliomas.

  4. these results suggest a potential relationship between SIRT3 (zeige SIRT3 ELISA Kits) enzymatic activity, IDH2-K413 acetylation-determined dimerization, and a cancer-permissive phenotype

  5. Identification of IDH1 (zeige IDH1 ELISA Kits) or IDH2 mutations supports the diagnosis of dedifferentiated chondrosarcoma rather than undifferentiated pleomorphic sarcoma of bone.

  6. There are frequent IDH2 R172 mutations in undifferentiated and poorly-differentiated sinonasal carcinomas.

  7. Results showed that TERT promoter mutational status combined with IDH-mutation allowed simple classification of grade II/III gliomas for stratifying patients and clarifying diagnostic accuracy by supplementing standard histopathological criteria.

  8. Results identified IDH2 rs11540478 as a new susceptibility locus for lung cancer.

  9. Functional studies demonstrated that IDH2 and PIK3CA (zeige PIK3CA ELISA Kits) hotspot mutations are likely drivers of solid papillary carcinoma with reverse polarity

  10. IDH1 (zeige IDH1 ELISA Kits) and IDH2 mutants inhibit TET-promoted oxidation of RNA 5-methylcytosine to 5hydroxymethylcytosine.

Cow (Bovine) Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) Interaktionspartner

  1. The enzyme is highly sensitive to Mg(2 (zeige MCOLN1 ELISA Kits)+) concentration in the physiological range, pointing to a potential regulatory role of [Mg(2 (zeige MCOLN1 ELISA Kits)+)] in mitochondrial energy metabolism.

Mouse (Murine) Isocitrate Dehydrogenase 2 (NADP+), Mitochondrial (IDH2) Interaktionspartner

  1. Findings demonstrate that IDH2 contributes to degeneration of the DA neuron in the neurotoxin model of Parkinson's Disease.

  2. IDH2 deficiency promotes mitochondrial dysfunction and cardiac hypertrophy in mice.

  3. IDH2 and NPM1 (zeige GJA1 ELISA Kits) mutations synergize in the development and maintenance of acute myeloid leukemia (zeige BCL11A ELISA Kits) stem-like cells.

  4. 7-Ketocholesterol inhibits isocitrate dehydrogenase 2 expression and impairs endothelial function via microRNA-144 leading to atherosclerosis.

  5. These data demonstrate the proto-oncogenic role of mutant IDH2.

  6. The tumor tissue of B16F10 cells transfected with IDH2 antisense cDNA exhibited induction of apoptosis and downregulation of angiogenesis markers.

  7. Data indicate that tumor tissues from idh2-/- ((knock-out) mice had significantly decreased HIF-1alpha (zeige HIF1A ELISA Kits) expression, blunted mRNA expression of HIF-1alpha (zeige HIF1A ELISA Kits), VEGF (zeige VEGFA ELISA Kits), and the glucose transport protein Glut-1 (zeige SLC1A3 ELISA Kits) was also observed.

  8. IDH2 mutants can cooperate with oncogenic Flt3 (zeige FLT3 ELISA Kits) or Nras (zeige NRAS ELISA Kits) alleles to drive leukemia in mice by impairing the differentiation of cells of the myeloid lineage

  9. SIRT3 (zeige SIRT3 ELISA Kits) protein deacetylates isocitrate dehydrogenase 2 (IDH2) and regulates mitochondrial redox status

  10. Results suggest that mitochondrial NADP(+)-dependent isocitrate dehydrogenase (zeige IDH1 ELISA Kits) plays a role in apoptosis induced by high glucose and may contribute to various pathologies associated with the long-term complications of diabetes.

IDH2 Antigen-Profil

Beschreibung des Gens

Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex.

Genbezeichner und Symbole assoziert mit IDH2

  • isocitrate dehydrogenase 2 (NADP+), mitochondrial (idh2) Antikörper
  • isocitrate dehydrogenase 2 (NADP+), mitochondrial (IDH2) Antikörper
  • Isocitrate dehydrogenase [NAD] regulatory subunit 2 (IDH2) Antikörper
  • isocitrate dehydrogenase 2 (NADP+), mitochondrial (Idh2) Antikörper
  • D2HGA2 Antikörper
  • E430004F23 Antikörper
  • F6P23.14 Antikörper
  • F6P23_14 Antikörper
  • ICD-M Antikörper
  • IDH Antikörper
  • Idh-2 Antikörper
  • IDH-II Antikörper
  • IDH2 Antikörper
  • IDHM Antikörper
  • IDP Antikörper
  • IDPm Antikörper
  • isocitrate dehydrogenase II Antikörper
  • isocitrate dehydrogenase subunit 2 Antikörper
  • mNADP-IDH Antikörper
  • NAD+ DEPENDENT ISOCITRATE DEHYDROGENASE SUBUNIT 2 Antikörper
  • wu:fb33c06 Antikörper
  • wu:fk31e05 Antikörper
  • wu:fq43b01 Antikörper
  • zgc:55485 Antikörper

Bezeichner auf Proteinebene für IDH2

isocitrate dehydrogenase 2 (NADP+), mitochondrial , isocitrate dehydrogenase [NADP], mitochondrial , isocitrate dehydrogenase [NADP], mitochondrial-like , NADP(+)-specific ICDH , oxalosuccinate decarboxylase , ICD-M , IDH , IDP , NADP+-specific isocitrate dehydrogenase , NADPH-specific isocitrate dehydrogenase

GENE ID SPEZIES
448026 Xenopus (Silurana) tropicalis
453645 Pan troglodytes
701480 Macaca mulatta
100155880 Sus scrofa
100441867 Pongo abelii
816218 Arabidopsis thaliana
3418 Homo sapiens
386951 Danio rerio
380013 Xenopus laevis
431056 Gallus gallus
327669 Bos taurus
269951 Mus musculus
361596 Rattus norvegicus
479043 Canis lupus familiaris
397603 Sus scrofa
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