anti-Interleukin-27 Subunit alpha (IL27) Antikörper

The protein encoded by IL27 is one of the subunits of a heterodimeric cytokine complex. Zusätzlich bieten wir Ihnen und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
IL27 246779 Q8K3I6
IL27 246778 Q8NEV9
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Top anti-IL27 Antikörper auf antikoerper-online.de

Showing 10 out of 16 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Maus Kaninchen HRP EIA, WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$636.30
Details
Maus Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$636.30
Details
Human Maus PE FACS 1 mL Anmelden zum Anzeigen 6 bis 8 Tage
$313.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$368.50
Details
Human Maus FITC FACS 1 mL Anmelden zum Anzeigen 6 bis 8 Tage
$308.00
Details
Human Kaninchen Unkonjugiert IF, IHC (p), WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$368.50
Details
Human Kaninchen Unkonjugiert EIA, IF, WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$469.32
Details
Human Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$469.32
Details
Human Maus Unkonjugiert FACS 0.5 mg Anmelden zum Anzeigen 6 bis 8 Tage
$533.50
Details
Human Maus Unkonjugiert ELISA   0.1 mg Anmelden zum Anzeigen 3 bis 4 Tage
$280.82
Details

IL27 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine)
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Human , , , ,
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Am meisten referenzierte anti-IL27 Antikörper

  1. Human Monoclonal IL27 Primary Antibody für ELISA - ABIN2474993 : Batten, Ghilardi: The biology and therapeutic potential of interleukin 27. in Journal of molecular medicine (Berlin, Germany) 2007 (PubMed)

Weitere Antikörper gegen IL27 Interaktionspartner

Mouse (Murine) Interleukin-27 Subunit alpha (IL27) Interaktionspartner

  1. endogenous levels of IL-27 affected the oncogenic properties of mutant p53 (zeige TP53 Antikörper) in vivo in a Li-Fraumeni mouse model. Lack of IL-27 signaling led to shortened survival times and increased incidence of osteosarcomas.

  2. Interleukin-27 is upregulated centrally and peripherally after intracerebral hemorrhage. Interleukin-27 promotes the tissue-protecting functions of neutrophils via, at least partly, the induction of lactoferrin (zeige LTF Antikörper).

  3. Serum IL-27 levels and cardiac IL-27 mRNA expression were significantly increased after LPS injection compared with control specimens.

  4. these findings highlight critical roles for IFN-gamma (zeige IFNG Antikörper) and IL-27 in the mechanism of respiratory syncytial virus-induced exacerbation

  5. IL-27-induced Sca-1 (zeige Ly6a Antikörper)(+) T cells had increased expression of effector/memory-associated transcription factor T-bet, Eomes (zeige EOMES Antikörper) and Blimp1 (zeige PRDM1 Antikörper).

  6. found that during respiratory virus infection the prototypic inflammatory cytokine IL-6 (zeige IL6 Antikörper) is a critical anti-inflammatory regulator of viral induced immunopathology in the respiratory tract through its induction of IL-27

  7. We demonstrate that IL-27-deficiency is linked to increased mucosal presence of ILC2 in a model of inflammatory lung disease. Moreover, IL-27-treatment inhibited ILC2 proliferation and cytokine production and significantly reduced their accumulation in vivo.

  8. These data suggest a novel role of the sympathetic neuroendocrine system for the modulation of IL-27-dependent acute inflammation.

  9. results identified a novel mechanism of action of IL-27 on Tregs in the context of cancers.

  10. These findings provide new evidence that IL-27 plays an important role in the proinflammatory capacity of monocytes and macrophages via enhancing IL-1beta (zeige IL1B Antikörper) secretion levels triggered by dual LPS (zeige TLR4 Antikörper)-ATP stimulation.

Human Interleukin-27 Subunit alpha (IL27) Interaktionspartner

  1. serum interleukin-27 and interleukin-35 concentrations in patients with Guillain-Barre syndrome

  2. Expression of IL-27 in the serum was markedly increased in patients with sepsis-induced myocardial dysfunction compared with that in controls.

  3. IL-27 significantly inhibited the M2 macrophages polarization and dampened the proliferation, migration and metastasis of pancreatic cancer cells and as well enhanced the efficacy of gemcitabine.

  4. IL-27 increased NLRP3 (zeige NLRP3 Antikörper) inflammasome activation in monocytes with enhanced release of IL-1 beta (zeige IL1B Antikörper).

  5. this study shows that interleukin 27 is up-regulated in patients with active inflammatory bowel disease

  6. IL-27 polymorphisms might play a protective role for the development of ulcerative colitis in the Mexican population

  7. IL-27 stimulation activated STAT1 (zeige STAT1 Antikörper) and STAT3 (zeige STAT3 Antikörper) in HeLa and T98G cells, suggesting that IL-27 engages the STAT1 (zeige STAT1 Antikörper)/3 pathway, which then leads to the upregulation of IL-6 (zeige IL6 Antikörper), IP-10 (zeige CXCL10 Antikörper), and MIG (zeige CXCL9 Antikörper)

  8. IL-27 and IL-37 limit the induction of particular T cell subsets along with cytokine responses in S. stercoralis infections, which suggest the importance of IL-27 and IL-37 in immune modulation in a chronic helminth infection.

  9. IL-27 is a pivotal regulator in endometriotic immune tolerance by triggering Th17 cells to produce IL-10 (zeige IL10 Antikörper).

  10. HIV and Tat (zeige TAT Antikörper) inhibit LPS (zeige IRF6 Antikörper)-induced IL-27 production in human macrophages via distinct mechanisms: Tat (zeige TAT Antikörper) through the inhibition of cIAP-1 (zeige BIRC2 Antikörper)-TRAF-6 (zeige TRAF6 Antikörper) and subsequent inhibition of PI3K (zeige PIK3CA Antikörper) and p38 (zeige CRK Antikörper) MAPKs, whereas HIV through the inhibition of p38 MAPK (zeige MAPK14 Antikörper) activation.

IL27 Antigen-Profil

Protein Überblick

The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

Genbezeichner und Symbole assoziert mit IL27

  • interleukin 27 (Il27) Antikörper
  • interleukin 27 (IL27) Antikörper
  • IL-27 Antikörper
  • IL-27A Antikörper
  • IL-27p28 Antikörper
  • IL27A Antikörper
  • IL27p28 Antikörper
  • IL30 Antikörper
  • p28 Antikörper

Bezeichner auf Proteinebene für IL27

IL-27 p28 subunit , IL-27 subunit alpha , IL-27-A , IL27-A , interleukin 30 , interleukin-27 subunit alpha

GENE ID SPEZIES
246779 Mus musculus
246778 Homo sapiens
Ausgewählte Anbieter für anti-IL27 (IL27) Antikörper
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