Interleukin 27 Proteine (IL27)

The protein encoded by IL27 is one of the subunits of a heterodimeric cytokine complex. Zusätzlich bieten wir Ihnen IL27 Antikörper (165) und IL27 Kits (48) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
IL27 53342 Q8TAD2
IL27 246779 Q8K3I6
IL27 365368  
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Top IL27 Proteine auf antikoerper-online.de

Showing 10 out of 27 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Human Cells Maus His tag 10 μg Anmelden zum Anzeigen 18 bis 20 Tage
287,50 €
Details
HOST_CHO Cells Human His tag 10 μg Anmelden zum Anzeigen 18 bis 20 Tage
287,50 €
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details
HOST_Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
Details
HOST_Escherichia coli (E. coli) Maus His tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
746,67 €
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HOST_Escherichia coli (E. coli) Ratte His tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
761,90 €
Details
HOST_Escherichia coli (E. coli) Maus Unkonjugiert   1 mg Anmelden zum Anzeigen 6 bis 8 Tage
6.105,30 €
Details
HOST_HEK293 Human Unkonjugiert   10 μg Anmelden zum Anzeigen 6 bis 8 Tage
564,96 €
Details
HOST_HEK-293 Cells Human Unkonjugiert   10 μg Anmelden zum Anzeigen 7 bis 9 Tage
447,62 €
Details

IL27 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
,
Mouse (Murine) , ,

Rat (Rattus)

Am meisten referenzierte IL27 Proteine

  1. Mouse (Murine) IL27 Protein expressed in Human Cells - ABIN2008620 : Pflanz, Timans, Cheung, Rosales, Kanzler, Gilbert, Hibbert, Churakova, Travis, Vaisberg, Blumenschein, Mattson, Wagner, To, Zurawski, McClanahan, Gorman, Bazan, de Waal Malefyt, Rennick, Kastelein: IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4+ T cells. in Immunity 2002 (PubMed)
    Zeige alle 5 Referenzen für 2008620

  2. Human IL27 Protein expressed in CHO Cells - ABIN2002020 : Fakruddin, Lempicki, Gorelick, Yang, Adelsberger, Garcia-Pineres, Pinto, Lane, Imamichi: Noninfectious papilloma virus-like particles inhibit HIV-1 replication: implications for immune control of HIV-1 infection by IL-27. in Blood 2007 (PubMed)
    Zeige alle 5 Referenzen für 2002020

  3. Human IL27 Protein expressed in Wheat germ - ABIN1307800 : Di Meo, Airoldi, Sorrentino, Zorzoli, Esposito, Di Carlo: Interleukin-30 expression in prostate cancer and its draining lymph nodes correlates with advanced grade and stage. in Clinical cancer research : an official journal of the American Association for Cancer Research 2014 (PubMed)
    Zeige alle 2 Referenzen für 1307800

Weitere Proteine zu Interleukin 27 (IL27) Interaktionspartnern

Human Interleukin 27 (IL27) Interaktionspartner

  1. These findings provide new evidence that IL-27 plays an important role in the proinflammatory capacity of monocytes and macrophages via enhancing IL-1beta (zeige IL1B Proteine) secretion levels triggered by dual LPS (zeige IRF6 Proteine)-ATP stimulation.

  2. IL-27 enhanced the cytotoxicity and suppressed the proliferation of ovarian cancer cells

  3. Study of the expression of IL-17 (zeige IL17A Proteine) provides theoretical support for the clinical treatment and prognosis prediction of ovarian epithelial tumor.

  4. the sIL (zeige PMEL Proteine)-6R/p28 (zeige PSMD10 Proteine) fusion protein (FP) upregulated IFN-lambda1 expression by increasing the binding abilities of c-Fos and activating transcription factor 1 (zeige AFT1 Proteine) to the IFN-lambda1 promoter via the p38 MAPK (zeige MAPK14 Proteine) signaling pathway; results demonstrate the important role of sIL (zeige PMEL Proteine)-6R/p28 (zeige PSMD10 Proteine) FP in mediating virus-induced type III IFN production.

  5. These results identify IL-27 and its specific receptor IL27RA (zeige IL27RA Proteine) as a critical immune axis for the antiviral immune response and as robust correlates of viral load and proviral reservoir size in mononuclear leukocytes in HIV infection.

  6. serum IL-27 levels were significantly higher in stage III EV71-infected hand, foot, and mouth disease patients with early cardiopulmonary failure and strong correlation with CRP (zeige CRP Proteine) levels; IL27p28 polymorphisms (rs153109, rs17855750, and rs181206) did not influence IL-27 production, and these three SNPs were not associated with EV71 infection risk and clinical stage

  7. these results suggest that IL-27 might predominantly play a protective role in the pathogenesis of psoriasis through abrogating Th17 differentiation.

  8. our data suggest a previously unrecognized role for IL-27 in regulating epithelial cell proliferation and antiviral host defense during the normal wound healing response.

  9. An association between the IL-27 single nucleotide polymorphism (SNP) rs153109 and Atrial Fibrillation was found in Chinese Han population. The G allele and GG genotype of rs153109 were associated with increased AF risk (odds ratio [OR]: 1.35, 95% confidence intervals [CI]=1.06-1.71, p=0.02 and OR: 1.66, 95% CI=1.03-2.65, p=0.03 in the recessive genetic model, respectively)

  10. Study demonstrated that levels of circulating serum IL-27 were elevated in rheumatoid arthritis (RA) patients and were positively correlated with RA disease activity. Moreover, these concentrations decreased after effective immunosuppressant treatment suggesting its involvement in the pathogenesis of RA.

Mouse (Murine) Interleukin 27 (IL27) Interaktionspartner

  1. These findings provide new evidence that IL-27 plays an important role in the proinflammatory capacity of monocytes and macrophages via enhancing IL-1beta (zeige IL1B Proteine) secretion levels triggered by dual LPS (zeige TLR4 Proteine)-ATP stimulation.

  2. findings show that PGE2 inhibits IL-27 production in macrophages and in splenic conventional dendritic cells; and identify a novel pathway consisting of signaling through EP2/EP4-->induction of cAMP-->downregulation of IFN regulatory factor 1 expression and binding to the p28 IFN-stimulated response element site

  3. these data provide the first evidence that IL-27 signals directly to B (zeige TDO2 Proteine) cells promote GCs (zeige UGCG Proteine) and support the role of IL-27 in lupus.

  4. this study shows that IL-27 plays an important role in immune response and pathogen clearance during infection with Candida parapsilosis

  5. Inhibition of IL-27p28 also enhanced the suppressive capacity of adoptively transferred CD4 (zeige CD4 Proteine)(+) nTregs by increasing the stability of Foxp3 (zeige FOXP3 Proteine) expression.

  6. These data provide evidence of a central role of IL-27 for the control of Th2-mediated allergic diseases.

  7. These data indicate that endogenous IL-27 limits pathology during parainfluenza virus infection

  8. our data suggest a previously unrecognized role for IL-27 in regulating epithelial cell proliferation and antiviral host defense during the normal wound healing response.

  9. recombinant IL-30 showed its biological activity by inhibiting Th17 differentiating from naive CD4 (zeige CD4 Proteine)(+) T cells. Therefore, this method of express and purifying IL-30 provides novel procedures to facilitate structural and functions studies of IL-30.

  10. An IL-27/Lag3 (zeige LAG3 Proteine) axis enhances Foxp3 (zeige FOXP3 Proteine)+ regulatory T cell-suppressive function and therapeutic efficacy.

Pig (Porcine) Interleukin 27 (IL27) Interaktionspartner

  1. The open reading frame of IL-27 p28 gene is 720 bp, which encodes a protein of 239 amino acids with a predicted molecular mass of 26.6 kDa. The deduced amino acid sequence of IL-27 p28 showed a high degree of homology to human (63%) and mouse (58%).

IL27 Protein Überblick

Protein Überblick

The protein encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

Genbezeichner und Symbole assoziert mit Interleukin 27 Proteine (IL27)

  • interleukin 27 (IL27)
  • interleukin 17D (IL17D)
  • interleukin 27 (Il27)
  • interleukin 27-like (LOC100349321)
  • IL-17D Protein
  • IL-22 Protein
  • IL-27 Protein
  • IL-27A Protein
  • IL-27p28 Protein
  • IL27 Protein
  • IL27A Protein
  • IL27p28 Protein
  • Il30 Protein
  • p28 Protein
  • RGD1561420 Protein

Bezeichner auf Proteinebene für Interleukin 27 Proteine (IL27)

interleukin 27 , interleukin-17D , interleukin-27 , IL-27 p28 subunit , IL-27 subunit alpha , IL-27-A , IL27-A , interleukin 30 , interleukin-27 subunit alpha , interleukin 27 p28 subunit , p28 , interluekin 27

GENE ID SPEZIES
737725 Pan troglodytes
53342 Homo sapiens
246778 Homo sapiens
246779 Mus musculus
365368 Rattus norvegicus
100724612 Cavia porcellus
493187 Sus scrofa
607880 Canis lupus familiaris
614927 Bos taurus
101122495 Ovis aries
101093822 Felis catus
100349321 Oryctolagus cuniculus
Ausgewählte Anbieter für IL27 Proteine (IL27)
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