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The protein encoded by IL18RAP is an accessory subunit of the heterodimeric receptor for IL18. Zusätzlich bieten wir Ihnen IL18RAP Antikörper (145) und IL18RAP Proteine (24) und viele weitere Produktgruppen zu diesem Protein an.
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These findings suggested that IL-18RAP rs917997, IL-32 (zeige IL32 ELISA Kits) rs2015620, IL-22 (zeige IL22 ELISA Kits) rs1179251, and interactions between these polymorphisms and H. pylori infection were associated with risks of gastric lesions
some SNPs of ST2-IL18R1-IL18RAP gene cluster might increase the risk of susceptibility of Graves' disease (GD) and Hashimoto's thyroiditis (HT) in Chinese Han population.
This meta-analysis provides robust estimates that IL18RAP rs917997 and chemokine (C-C motif) receptor 3 (zeige CCR3 ELISA Kits) rs6441961 are potential risk factors for celiac disease in European populations.
results demonstrate clear functional consequences of the rs917997 risk polymorphism; this polymorphism leads to a loss-of-function through decreased IL-18RAP, IL-18R1 (zeige IL18R1 ELISA Kits), and IL-1R1 protein expression, which impairs autocrine IL-18 (zeige IL18 ELISA Kits) and IL-1 (zeige IL1A ELISA Kits) signaling
The SNP modified IL18RAP surface protein expression by NK cells.
Data indicate that MyD88 works together with the IL-1/IL-18 receptors, can interact with two distinct sorting adaptors, TRAM and Mal, in a conserved manner.
Data suggest that IL-18RAP and IL-18R1 (zeige IL18R1 ELISA Kits) single-nucleotide polymorphisms identify African-American infants at risk for bronchopulmonary dysplasia.
IL-18 (zeige IL18 ELISA Kits), IL-18 receptor alpha (zeige IL18R1 ELISA Kits), and CD48 (zeige CD48 ELISA Kits) complex formation via glycosylphosphatidylinositol anchor glycan triggers binding to IL-18 receptor beta, and thereby induces intracellular signal transduction and IFN-gamma (zeige IFNG ELISA Kits) production.
Truncated forms of IL-18RAP may be involved in the complex mechanism of IL-18 (zeige IL18 ELISA Kits) activity regulation.
Variations in IL18RAP is associated with celiac disease
Our data highlight the considerable complexity of the IL-18 (zeige IL18 ELISA Kits) regulation activity in the mouse brain and further support an important central role for IL-18 (zeige IL18 ELISA Kits).
This study demonstrates that IL-18 (zeige IL18 ELISA Kits) signals are abolished in accessory protein-like (AcPL)-deficient mice and cells, and suggests that AcPL is a critical and specific cell surface receptor required for IL-18 (zeige IL18 ELISA Kits) signaling.
The protein encoded by this gene is an accessory subunit of the heterodimeric receptor for IL18. This protein enhances the IL18 binding activity of IL18R1 (IL1RRP), a ligand binding subunit of IL18 receptor. The coexpression of IL18R1 and this protein is required for the activation of NF-kappaB and MAPK8 (JNK) in response to IL18.
interleukin 18 receptor accessory protein
, IL-18 receptor beta
, interleukin-18 receptor accessory protein-like
, CD218 antigen-like family member B
, IL-18 receptor accessory protein
, interleukin-1 receptor 7
, interleukin-18 receptor accessory protein
, interleukin-18 receptor beta
, AcPL accessory protein-like)