anti-Interferon Regulatory Factor 6 (IRF6) Antikörper

IRF6 encodes a member of the interferon regulatory transcription factor (IRF) family. Zusätzlich bieten wir Ihnen IRF6 Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
IRF6 3664 O14896
IRF6 54139 P97431
IRF6 364081  
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Top anti-IRF6 Antikörper auf antikoerper-online.de

Showing 10 out of 98 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-IRF6 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:12500<br><b>Positive Control: </b>Transfected 293T Immunohistochemistry with Placenta tissue at an antibody concentration of 5µg/ml using anti-IRF6 antibody (ARP31995_P050) 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-IRF6 Antibody Titration: </b>2.5ug/ml<br><b>Positive Control: </b>Jurkat cell lysate WB Suggested Anti-IRF6 <br /> Antibody Titration: 2.5 µg/mL <br /> Positive Control: Jurkat cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-IRF6 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>293T cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Rabbit <br /> Target Name: IRF6 <br /> Sample Tissue: Human Adult Placenta <br /> Antibody Dilution: 1.0 µg/mL 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert IHC, ELISA, WB ABIN184730 staining (0.2µg/ml) of Human Ovary lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$326.89
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Fledermaus Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$493.17
Details
Fledermaus Kaninchen Unkonjugiert IHC (p), WB Anti-IRF6 antibody IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody  ABIN958994 concentration 5 ug/ml. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$676.50
Details
Human Ziege Unkonjugiert ELISA, IHC, IHC (p), WB Immunohistochemistry-Paraffin: IRF6 Antibody [NBP1-51911] - staining. Western Blot: IRF6 Antibody [NBP1-51911] - Western blot analysis of IRF6 in Human Ovary lysate using NBP1-51911 at 0.2 ug/ ml. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$447.56
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details

IRF6 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-IRF6 Antikörper

  1. Human Polyclonal IRF6 Primary Antibody für ELISA, IHC - ABIN4327608 : Hu, Liu, Li, Ozturk, Gurumurthy, Romano, Sinha, Nawshad: TGFβ3 regulates periderm removal through ΔNp63 in the developing palate. in Journal of cellular physiology 2015 (PubMed)
    Show all 5 Pubmed References

  2. Cow (Bovine) Polyclonal IRF6 Primary Antibody für IHC, WB - ABIN2779406 : Iwata, Suzuki, Pelikan, Ho, Sanchez-Lara, Urata, Dixon, Chai: Smad4-Irf6 genetic interaction and TGF?-mediated IRF6 signaling cascade are crucial for palatal fusion in mice. in Development (Cambridge, England) 2013 (PubMed)

Weitere Antikörper gegen IRF6 Interaktionspartner

Human Interferon Regulatory Factor 6 (IRF6) Interaktionspartner

  1. IRF6 is aberrantly silenced by DNA methylation (zeige HELLS Antikörper) of the 5' IRF6 CGI in melanoma

  2. In all three affecteds the known pathogenic mutation c.265A>G, p.Lys89Glu in IRF6 was identified. While inter- as well as intra-familial variability has been described in IRF6-related disorders, the occurrence of a typical Van (zeige TNIP1 Antikörper) der (zeige GDF3 Antikörper) Woude Syndrome without any other anomalies as well as a diagnosis of Popliteal pterygium syndrome in the same family is rare.

  3. Association between IRF6 and 8q24 polymorphisms and nonsyndromic cleft lip with or without cleft palate

  4. Here, we demonstrate the protein functions of human IRF6 missense gene variants could be rapidly assessed in detail by their abilities to rescue the irf6 -/- phenotype in zebrafish through variant mRNA microinjections at the one-cell stage.

  5. The data presented suggest an important role for cytoplasmic IRF6 in regulating the availability or localization of the NME1 (zeige NME1 Antikörper)/2 complex and thus the dynamic behavior of epithelia during lip/palate development.

  6. IRF6 dysregulation may be involved in the development of Vulvar Squamous Cell Carcinoma from vulvar lichen sclerosus (VLS). Methylation of the IRF6 promoter may be a marker of cancer risk in patients with VLS.

  7. Here, the authors have established that IRF6 promotes the differentiation of oral keratinocytes in response to Porphyromonas gingivalis.

  8. It has been shown that pathogenic IRF6 mutations are likely to occur in a small fraction (~0.3%) of individuals with apparent nonsyndromic orofacial cleft, across multiple ethnic groups.

  9. The 8q24 region plays a role in cleft lip/palate and the IRF6 G/A haplotype (rs2235371/rs642961) increases the risk for oral cleft in the Brazilian population.

  10. Studied the correlation of IRF6 rs642961 polymorphism and NSCL (zeige NHLH1 Antikörper)/P in Iranian NSCL (zeige NHLH1 Antikörper)/P families; the family-based association analysis revealed no significant association between IRF6 rs642961 genotypes and an increased NSCL (zeige NHLH1 Antikörper)/P risk.

Zebrafish Interferon Regulatory Factor 6 (IRF6) Interaktionspartner

  1. Here, we demonstrate the protein functions of human IRF6 missense gene variants could be rapidly assessed in detail by their abilities to rescue the irf6 -/- phenotype in zebrafish through variant mRNA microinjections at the one-cell stage.

  2. Fish IRF6 is distinguished from the homolog of mammals by being a positive regulator of IFN transcription and phosphorylated by MyD88 (zeige MYD88 Antikörper) and TBK1 (zeige TBK1 Antikörper), suggesting that differences in the IRF6 regulation pattern exist between lower and higher vertebrates.

  3. Authors report that Kruppel-like factor 17 (Klf17 (zeige KLF17 Antikörper)), like Grhl3 (zeige GRHL3 Antikörper), acts downstream of Irf6 in this network in zebrafish periderm.

  4. In zebrafish periderm, grainyhead-like 3 (grhl3 (zeige GRHL3 Antikörper)) (an ancient regulator of the epidermal permeability barrier), was identified as acting downstream of Irf6. Simultaneous inhibition of grhl1 (zeige GRHL1 Antikörper) and grhl3 (zeige GRHL3 Antikörper) disrupted periderm differentiation in zebrafish.

  5. analysis of zebrafish expression of IRF6

  6. These experiments reveal a conserved role for maternally-encoded Irf6 in differentiation of a simple epithelium in X. laevis and D. rerio.

Mouse (Murine) Interferon Regulatory Factor 6 (IRF6) Interaktionspartner

  1. IRF6 suppresses PPARgamma (zeige PPARG Antikörper) through binding IRF (zeige TRIM63 Antikörper) recognition sites located upstream of the PPARgamma (zeige PPARG Antikörper) coding region. Taken together, the results suggest that an IRF6/PPARgamma (zeige PPARG Antikörper) regulatory axis suppresses anti-inflammatory responses in bone marrow-derived macrophages and provides references for future study addressing dysregulated metabolic and immunologic homeostasis of obese adipose tissue.

  2. Irf6 and RTK signaling interact in regulating periderm differentiation and function, as well as provide a rationale to screen for epistatic interactions between variants in IRF6 and RTK signaling pathway genes in human orofacial clefting populations.

  3. These data provide the first mechanistic insight into the heightened caries susceptibility associated with CLP (zeige HAPLN1 Antikörper) and indicate a direct role for the major CLP (zeige HAPLN1 Antikörper) gene Irf6 in salivary gland development and a significant role in regulating oral immunity in mice.

  4. that downregulation of interferon regulatory factor 6 affords protection against TNI (zeige TNNI2 Antikörper) through Akt (zeige AKT1 Antikörper)-eNOS (zeige NOS3 Antikörper) pathway-mediated antioxidative and anti-inflammatory activity

  5. Irf6 is required for resistance to Lipopolysaccharides-induced endotoxic shock. In addition, Irf6-deficient bone marrow-derived neutrophils exhibited increased chemotactic index and velocity compared with wild-type cells in vitro.

  6. TGFbeta3 increases IRF6 expression and subsequently regulates SNAI2 expression; IRF6 appears to regulate epithelial mesenchymal transition during palatal fusion via SNAI2.

  7. Pvrl1 (zeige PVRL1 Antikörper) is a bona fide target gene of the transcription factor p63 (zeige CKAP4 Antikörper), whereas Pvrl4 (zeige PVRL4 Antikörper) regulation is linked to epidermal differentiation and is under Irf6

  8. Data suggest that Irf6 functions through the RhoA (zeige RHOA Antikörper) pathway to regulate cellular migration.

  9. These results support a role for IRF6 in brain morphometry and provide evidence for a potential genetic link to abnormal brain development in orofacial clefting.

  10. Irf6 plays important cell-autonomous and non-cell-autonomous roles in muscular differentiation and cytoskeletal formation in the tongue.

IRF6 Antigen-Profil

Protein Überblick

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit IRF6

  • interferon regulatory factor 6 (IRF6) Antikörper
  • interferon regulatory factor 6 (irf6) Antikörper
  • interferon regulatory factor 6 S homeolog (irf6.S) Antikörper
  • interferon regulatory factor 6 (Irf6) Antikörper
  • AI876454 Antikörper
  • DKFZp469E012 Antikörper
  • E230028I05Rik Antikörper
  • IRF6 Antikörper
  • LPS Antikörper
  • mirf6 Antikörper
  • OFC6 Antikörper
  • PIT Antikörper
  • PPS Antikörper
  • PPS1 Antikörper
  • VWS Antikörper
  • VWS1 Antikörper
  • xIRF-6 Antikörper
  • zgc:63500 Antikörper

Bezeichner auf Proteinebene für IRF6

interferon regulatory factor 6 , interferon regulatory factor 6-like , IRF-6

GENE ID SPEZIES
443083 Ovis aries
457701 Pan troglodytes
594908 Xenopus (Silurana) tropicalis
712958 Macaca mulatta
100174467 Pongo abelii
100402804 Callithrix jacchus
100594750 Nomascus leucogenys
3664 Homo sapiens
393570 Danio rerio
443771 Xenopus laevis
480015 Canis lupus familiaris
397521 Sus scrofa
614253 Bos taurus
54139 Mus musculus
364081 Rattus norvegicus
100349520 Oryctolagus cuniculus
419863 Gallus gallus
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