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The protein encoded by ID3 is a helix-loop-helix (HLH) protein that can form heterodimers with other HLH proteins. Zusätzlich bieten wir Ihnen Inhibitor of DNA Binding 3, Dominant Negative Helix-Loop-Helix Protein Antikörper (144) und Inhibitor of DNA Binding 3, Dominant Negative Helix-Loop-Helix Protein Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.
The results of the present study revealed that overexpression of Id3 may serve as a novel strategy for inhibiting cisplatinsensitive lung cancer.
Results show that ID1 (zeige ID1 ELISA Kits), ID3 and IGJ (zeige IGJ ELISA Kits) genes are highly expressed in adult B-ALL and correlate with poor prognosis in Hispanic patients.
Upon Id3 transfection, A549 cells displayed decreased migratory and invasive capabilities, however, co-transfection of miRId3 and Id3 into A549 cells reversed the Id3-induced inhibitions of migratory and invasive capabilities.
Inhibitor of differentiation 4 (ID4 (zeige ID4 ELISA Kits)) acts as an inhibitor of ID-1 (zeige ID1 ELISA Kits), -2 and -3 and promotes basic helix loop helix (bHLH) E47 (zeige TCF3 ELISA Kits) DNA binding and transcriptional activity.
ID3 has a role in the acquisition of molecular stem cell-like signature in microvascular endothelial cells
our data provide evidence that ID3 may play a critical role in regulating vascular endothelial cell survival and development of microvascular lesions induced by persistent environmental pollutants such as PCB153.
ID3 plays a potential role in the underlying regulatory mechanisms of metabolic health in human obesity. [Review]
Epigenetic changes in ID3, in combination with experiences of maltreatment, may confer risk for depression in children.
Data indicate association of inhibitor of differentiation 3 (ID3) single nucleotide polymorphism rs11574 directly with coronary artery pathology.
Importantly, the distinct ID3 expression patterns in acute leukemias (AL) indicate a specific deregulation of ID3 in the various types of AL and may support subtyping of AL.
The present study provides additional support for roles for ID3 in the etiology of depression following early adversity.
Our work identifies a distinct premalignant state and multiple tumorigenic pathways caused by loss of function of Id2 and Id3
down-regulation of Id3 in B cells is essential for releasing E2A (zeige TCF3 ELISA Kits) and E2-2 (zeige TCF4 ELISA Kits), which in a redundant manner are required for antigen-induced B cell differentiation.
Results found that Id3 expression is high in follicular B lineage cells but declines in germinal center (GC) cells. However, during the GC reaction, Id3 levels decline to activate the expression of genes encoding signaling components that mediate B cell receptor- and or cytokine receptor (zeige LEPR ELISA Kits)-mediated signaling to promote the differentiation of GC B (zeige NPR2 ELISA Kits) cells.
These results identify Id3 as the BMP-2 (zeige BMP2 ELISA Kits)-induced transcriptional regulator, promoting adult NSPC differentiation into astrocytes upon CNS injury
Inflammation-induced S100A8 (zeige S100A8 ELISA Kits) promotes colorectal tumorigenesis by acting upstream to activate the Akt1 (zeige AKT1 ELISA Kits)-Smad5 (zeige SMAD5 ELISA Kits)-Id3 axis.
Data show that enforced expression of inhibitor of differentiation protein Id3 specifically increased the persistence of Cd244 (zeige CD244 ELISA Kits) protein 2B4 (zeige CD244 ELISA Kits)(+) virus-specific CD8 (zeige CD8A ELISA Kits)(+) T cells.
ID2/3 are crucial regulators of the adaptive antioxidant-mitochondrial response that promotes beta cell survival during oxidative stress through a novel link to the NFE2L2 (zeige NFE2L2 ELISA Kits)-small MAF (zeige MAF ELISA Kits) pathway.
Enhanced IL-13 (zeige IL13 ELISA Kits) production by T cells can play a causative role in the exocrinopathy observed in Id3 knockout mice.
Tob1 and Tob2 (zeige TOB2 ELISA Kits) inhibit the cell cycle via degradation of Id3 mRNA, which is a set of directly targeted genes of BMP4 (zeige BMP4 ELISA Kits) signaling in embryonic stem cells.
Data revealed that expression of DNA binding inhibitor 3, early B cell factor 2, Ebf3, Iroquois related homeobox 1, Kruppel-like factor 7 , mab-21-like 1 , fatty acid binding protein 7 and stathmin-like 4,were enriched in the diencephalon of zebrafish.
expression of id3 in zebrafish embryo
Results provide evidence that the helix-loop-helix factor Id3 mediates the mitogenic effect of hyperlipemic sera and ox-LDL in VSMC via inhibition of p21cip1 (zeige CDKN1A ELISA Kits) expression, subsequently increasing DNA synthesis and proliferation
The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with other HLH proteins. However, the encoded protein lacks a basic DNA-binding domain and therefore inhibits the DNA binding of any HLH protein with which it interacts.
DNA-binding protein inhibitor ID-3
, ID-like protein inhibitor HLH 1R21
, class B basic helix-loop-helix protein 25
, helix-loop-helix protein HEIR-1
, ID-like protein inhibitor HLH 462
, Inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
, helix-loop-helix protein
, inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
, olfactory receptor 136-6
, olfactory receptor I-D3
, olfactory receptor MOR136-6
, DNA-binding protein inhibitor ID-3-B
, Inhibitor of DNA binding 3-B