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Serves to link two monomer units of either IgM or IgA. Zusätzlich bieten wir Ihnen IGJ Antikörper (66) und IGJ Kits (8) und viele weitere Produktgruppen zu diesem Protein an.
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Human IGJ Protein expressed in Escherichia coli (E. coli) - ABIN1098584
Liu, Qian, Gritsenko, Camp, Monroe, Moore, Smith: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry. in Journal of proteome research 2005
Zeige alle 2 Referenzen für 1098584
Human IGJ Protein expressed in Escherichia coli (E. coli) - ABIN2005369
Koshland: The coming of age of the immunoglobulin J chain. in Annual review of immunology 1986
Results show that ID1 (zeige ID1 Proteine), ID3 (zeige ID3 Proteine) and IGJ genes are highly expressed in adult B-ALL and correlate with poor prognosis in Hispanic patients.
TLR2 ligands induce CCR9 and CCR10 expression by circulating B-cells and increase their chemotaxis. TLR2 stimulation also induced J chain and IgA production demonstrating the induction of mucosal-like antibody secreting cells.
Data show that Crlz1 (zeige UTP3 Proteine) increased the IgJ enhancer activity due to its CBF sites, as verified by both the absence of Crlz1 (zeige UTP3 Proteine) effect on the CBF-site mutated IgJ enhancer and the presence of transcriptional synergy between Crlz1 (zeige UTP3 Proteine) and CBFbeta (zeige CBFB Proteine).
identifies the HSS3/4 enhancer of Crlz1 (zeige UTP3 Proteine)-IgJ locus as another target of EBG in early developmental stage of B cells
H3 and H4 histones toward the chromatin of the Crlz1 (zeige UTP3 Proteine) gene are found to be hyperacetylated, especially on H3, in the pre-B cells, whereas those toward the chromatin of the IgJ gene are found to be hyperacetylated in the plasma cells
Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.
immunoglobulin J chain
, mu- and alpha-immunoglobulin-associated J chain
, IgJ chain
, J chain
, immunoglobulin joining gene (not J region)