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Increases intracellular lipid accumulation. Zusätzlich bieten wir Ihnen HILPDA Antikörper (11) und HILPDA Kits (5) und viele weitere Produktgruppen zu diesem Protein an.
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Thus, macrophage Hilpda is crucial to foam-cell formation and lipid deposition, and to controlled prostaglandin-E2 production. By these means Hilpda promotes lesion formation and progression of atherosclerosis
HILPDA is highly abundant in adipose tissue, where its levels are induced by peroxisome proliferator-activated receptor gamma (zeige PPARG Proteine) and beta-adrenergic stimulation. In contrast to the reported inhibition of lipolysis by HILPDA in hepatocytes, those data do not support an important direct role of HILPDA in the regulation of lipolysis in adipocytes in vivo and in vitro.
When fasted, HILPDA KO mice are unable to maintain body temperature and become hypothermic at 22 degrees C.
data uncover HILPDA as a novel PPAR (zeige PPARA Proteine) target that raises hepatic triglyceride storage via regulation of triglyceride secretion.
HIG2 was up-regulated by hypoxia and HIF inducers in all cell types and mouse organs investigated and abundantly expressed in renal clear-cell carcinomas
Data indicate that HIG2 (hypoxia-inducible gene 2) is a HIF-1alpha (zeige HIF1A Proteine) target in regulating cell survival during hypoxia.
there was no significant relationship between HIG2 expression and age, clinical stage and histology in either cervical cancer or endometrial cancer.
Data show that DBN1 (zeige DBN1 Proteine), SETMAR (zeige SETMAR Proteine) and HIG2 are direct transcriptional targets of the SOX11 (zeige SOX11 Proteine) protein.
Increases intracellular lipid accumulation. Stimulates expression of cytokines including IL6, MIF and VEGFA. Enhances cell growth and proliferation (By similarity).
hypoxia-inducible gene 2 protein
, hypoxia-inducible lipid droplet-associated protein
, hypoxia inducible gene 2
, hypoxia-inducible protein 2