Hyaluronan and Proteoglycan Link Protein 1 Proteine (HAPLN1)

Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.. Zusätzlich bieten wir Ihnen HAPLN1 Antikörper (52) und HAPLN1 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
HAPLN1 1404 P10915
HAPLN1 12950 Q9QUP5
HAPLN1 29331  
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Showing 10 out of 10 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Human Cells Human His tag 50 μg Anmelden zum Anzeigen 18 bis 20 Tage
450,00 €
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 7 bis 8 Tage
235,20 €
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.779,69 €
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Hefe Pferd His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.779,69 €
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Hefe Wildschwein His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.797,14 €
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.797,14 €
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Hefe Huhn His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.798,89 €
Details
HOST_Escherichia coli (E. coli) Human Unkonjugiert   50 μg Anmelden zum Anzeigen 6 bis 8 Tage
495,58 €
Details

HAPLN1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
,
Mouse (Murine)

Rat (Rattus)

Am meisten referenzierte HAPLN1 Proteine

  1. Human HAPLN1 Protein expressed in Human Cells - ABIN2002566 : Sun, Kobayashi, Suzuki, Kanayama, Terao: Production of cartilage link protein by human granulosa-lutein cells. in The Journal of endocrinology 2002 (PubMed)
    Zeige alle 3 Referenzen für 2002566

  2. Human HAPLN1 Protein expressed in Wheat germ - ABIN1306351 : Mathur, Blais, Goparaju, Neubert, Pass, Levon: Development of a biosensor for detection of pleural mesothelioma cancer biomarker using surface imprinting. in PLoS ONE 2013 (PubMed)

Weitere Proteine zu Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) Interaktionspartnern

Zebrafish Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) Interaktionspartner

  1. Hapln1a-ECM (zeige MMRN1 Proteine) stabilizes the secreted growth factor (zeige WNT2 Proteine) Semaphorin3d (Sema3d (zeige SEMA3D Proteine)), which has been independently shown to mediate Cx43 (zeige GJA1 Proteine) dependent phenotypes during regeneration.

  2. Hapln1a has a critical role in connexin43 (zeige GJA1 Proteine)-dependent growth and patterning in the regenerating fin skeleton

  3. The cloning and characterization of crtl1 and its expression during embryogenesis are reported.

Cow (Bovine) Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) Interaktionspartner

  1. stimulates proteoglycan (zeige Vcan Proteine) and types II and IX collagens in intervertebral disc cells - stimulates synthesis of matrix molecules

Human Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) Interaktionspartner

  1. CSGalNAcT-1 (zeige CSGALNACT1 Proteine) and Hapln-1 may play important roles in the pathogenesis of Kashin-Beck disease and osteoarthritis.

  2. HAPLN1 is overexpressed in metastatic melanoma and is secreted exclusively by the tumor cells

  3. Single-nucleotide polymorphism in the hyaluronan and proteoglycan link protein 1 (HAPLN1) gene is associated with spinal osteophyte formation and disc degeneration in Japanese women.

  4. An in vitro model of perineuronal nets has been developed demonstrating that cartilage link protein (along with hyaluronan synthase) are necessary for their formation.

  5. link protein may function as a stabilizer of the interaction between aggrecan (zeige ACAN Proteine) and hyaluronan in cartilage and between versican (zeige Vcan Proteine) and hyaluronan in many tissues

  6. SOX9 (zeige SOX9 Proteine) is a key regulator of CRTL1

  7. cLP (zeige CALML3 Proteine) and versican (zeige Vcan Proteine) did not bind directly to each other in solution yet formed ternary complexes with hyaluronan

  8. Overexpression of HAPLN1 and its SP-IgV domain increases tumorigenic properties of mesothelioma. Thus, targeting the SP-IgV domain may be one of the therapeutic approaches in cancer treatment.

Mouse (Murine) Hyaluronan and Proteoglycan Link Protein 1 (HAPLN1) Interaktionspartner

  1. Aggrecan (zeige ACAN Proteine), link protein and TN-R (zeige TNR Proteine) were identified to be essential for the neuroprotective properties of the perineuronal net.

  2. Mef2c (zeige MEF2C Proteine) regulates transcription of the extracellular matrix protein cartilage link protein 1 in the developing murine heart.

  3. our findings demonstrate that the formation of perineuronal nets triggered by neuronal Crtl1 synthesis is a key event in the diminuation of plasticity in the adult CNS

  4. there is a general and systemic function of link protein in the organization of extracellular matrix in a number of tissues, possibly interacting with other proteoglycans, such as versican (zeige Vcan Proteine), brevican (zeige BCAN Proteine), and neurocan (zeige NCAN Proteine)

  5. Data suggest that the reported temporal co-expression of cartilage link protein and neurocan (zeige NCAN Proteine) in developing brain implicates the possibility of a cooperative function of these molecules.

  6. reduced versican (zeige Vcan Proteine) expression may contribute to a subset of the cardiac abnormalities observed in the Crtl1(-/-) mouse.

HAPLN1 Protein Überblick

Protein Überblick

Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.

Genbezeichner und Symbole assoziert mit HAPLN1

  • hyaluronan and proteoglycan link protein 1 (HAPLN1)
  • hyaluronan and proteoglycan link protein 1a (hapln1a)
  • hyaluronan and proteoglycan link protein 1 (Hapln1)
  • BB099155 Protein
  • CLP Protein
  • Crtl1 Protein
  • Crtl1l Protein
  • CTRL1 Protein
  • hapln1 Protein
  • LP Protein
  • LP-1 Protein
  • wu:fc26f11 Protein
  • wu:fc37g04 Protein
  • wu:fc50e12 Protein
  • wu:fc55h01 Protein

Bezeichner auf Proteinebene für HAPLN1

hyaluronan and proteoglycan link protein 1 , cartilage linking protein 1 , fc26f11 , fc37g04 , fc50e12 , fc55h01 , hyaluronan proteoglycan link protein 1 , cartilage link protein , cartilage-link protein , cartilage-linking protein 1 , proteoglycan link protein , Cartilage link protein , cartilage link protein 1 , link protein , LP , link protein precursor (AA -15 to 339)

GENE ID SPEZIES
461765 Pan troglodytes
488921 Canis lupus familiaris
493635 Danio rerio
712501 Macaca mulatta
100442758 Pongo abelii
100605865 Nomascus leucogenys
281717 Bos taurus
1404 Homo sapiens
12950 Mus musculus
29331 Rattus norvegicus
396475 Gallus gallus
100034208 Equus caballus
445513 Sus scrofa
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