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Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.. Zusätzlich bieten wir Ihnen HAPLN1 Antikörper (52) und HAPLN1 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.
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Human HAPLN1 Protein expressed in Wheat germ - ABIN1306351
Mathur, Blais, Goparaju, Neubert, Pass, Levon: Development of a biosensor for detection of pleural mesothelioma cancer biomarker using surface imprinting. in PLoS ONE 2013
Hapln1a-ECM (zeige MMRN1 Proteine) stabilizes the secreted growth factor (zeige WNT2 Proteine) Semaphorin3d (Sema3d (zeige SEMA3D Proteine)), which has been independently shown to mediate Cx43 (zeige GJA1 Proteine) dependent phenotypes during regeneration.
Hapln1a has a critical role in connexin43 (zeige GJA1 Proteine)-dependent growth and patterning in the regenerating fin skeleton
The cloning and characterization of crtl1 and its expression during embryogenesis are reported.
stimulates proteoglycan (zeige Vcan Proteine) and types II and IX collagens in intervertebral disc cells - stimulates synthesis of matrix molecules
CSGalNAcT-1 (zeige CSGALNACT1 Proteine) and Hapln-1 may play important roles in the pathogenesis of Kashin-Beck disease and osteoarthritis.
HAPLN1 is overexpressed in metastatic melanoma and is secreted exclusively by the tumor cells
Single-nucleotide polymorphism in the hyaluronan and proteoglycan link protein 1 (HAPLN1) gene is associated with spinal osteophyte formation and disc degeneration in Japanese women.
An in vitro model of perineuronal nets has been developed demonstrating that cartilage link protein (along with hyaluronan synthase) are necessary for their formation.
link protein may function as a stabilizer of the interaction between aggrecan (zeige ACAN Proteine) and hyaluronan in cartilage and between versican (zeige Vcan Proteine) and hyaluronan in many tissues
SOX9 (zeige SOX9 Proteine) is a key regulator of CRTL1
cLP (zeige CALML3 Proteine) and versican (zeige Vcan Proteine) did not bind directly to each other in solution yet formed ternary complexes with hyaluronan
Overexpression of HAPLN1 and its SP-IgV domain increases tumorigenic properties of mesothelioma. Thus, targeting the SP-IgV domain may be one of the therapeutic approaches in cancer treatment.
Aggrecan (zeige ACAN Proteine), link protein and TN-R (zeige TNR Proteine) were identified to be essential for the neuroprotective properties of the perineuronal net.
Mef2c (zeige MEF2C Proteine) regulates transcription of the extracellular matrix protein cartilage link protein 1 in the developing murine heart.
our findings demonstrate that the formation of perineuronal nets triggered by neuronal Crtl1 synthesis is a key event in the diminuation of plasticity in the adult CNS
there is a general and systemic function of link protein in the organization of extracellular matrix in a number of tissues, possibly interacting with other proteoglycans, such as versican (zeige Vcan Proteine), brevican (zeige BCAN Proteine), and neurocan (zeige NCAN Proteine)
Data suggest that the reported temporal co-expression of cartilage link protein and neurocan (zeige NCAN Proteine) in developing brain implicates the possibility of a cooperative function of these molecules.
reduced versican (zeige Vcan Proteine) expression may contribute to a subset of the cardiac abnormalities observed in the Crtl1(-/-) mouse.
Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.
hyaluronan and proteoglycan link protein 1
, cartilage linking protein 1
, hyaluronan proteoglycan link protein 1
, cartilage link protein
, cartilage-link protein
, cartilage-linking protein 1
, proteoglycan link protein
, Cartilage link protein
, cartilage link protein 1
, link protein
, link protein precursor (AA -15 to 339)