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The product encoded by HCFC2 is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. Zusätzlich bieten wir Ihnen Host Cell Factor C2 Antikörper (46) und viele weitere Produktgruppen zu diesem Protein an.
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The plasma level of alpha2M was found positively correlated, while HCII (zeige SERPIND1 Proteine) level was negatively correlated with higher vulnerability of carotid plaques. Both proteins were efficient in differentiating stable and vulnerable carotid plaques. These provide potential new targets for the research of carotid plaque vulnerability. Plasma alpha2M and HCII (zeige SERPIND1 Proteine) may be potential biomarkers for evaluation of the vulnerability of carotid ...
We found that SERPIND1 (zeige SERPIND1 Proteine) may act as a potential oncogene (zeige RAB1A Proteine) in the development of ovarian cancer
Molecular modelling of HCII (zeige SERPIND1 Proteine) 1-75 predicted those portions of the acidic extension that had been previously visualized in crystal structures, and suggested that an alpha-helix found between residues 26 and 36 stabilizes one found between residues 61-67.
In this study, we demonstrate a previously unknown role for HCII (zeige SERPIND1 Proteine) in host defense.
HCII (zeige SERPIND1 Proteine) potentiates the activation of vascular endothelial cells and the promotion of angiogenesis in response to hindlimb ischemia via an AMPK (zeige PRKAA1 Proteine)-eNOS (zeige NOS3 Proteine) signaling pathway.
Plasma heparin cofactor II (zeige SERPIND1 Proteine) activity was independently and inversely associated with the development of cardiac remodeling, including cardiac concentric change, left atrial enlargement and left ventricular diastolic dysfunction.
[REVIEW]HCII (zeige SERPIND1 Proteine) protects against vascular remodeling, including atherosclerosis
potential for oversulfated disaccharides in controlling HCII (zeige SERPIND1 Proteine)-regulated thrombin (zeige F2 Proteine) generation
Aspartic acid residues 72 and 75 and tyrosine-sulfate 73 of heparin cofactor II (zeige SERPIND1 Proteine) promote
role of basic amino acids of the A helix of heparin cofactor II (zeige SERPIND1 Proteine) in heparin- or dermatan sulfate-mediated thrombin (zeige F2 Proteine) inhibition.
The product encoded by this gene is a serine proteinase inhibitor which rapidly inhibits thrombin in the presence of dermatan sulfate or heparin. The gene contains five exons and four introns. This protein shares homology with antithrombin III and other members of the alpha 1-antitrypsin superfamily. Mutations in this gene are associated with heparin cofactor II deficiency.
, host cell factor 2
, heparin cofactor 2
, leuserpin 2
, protease inhibitor leuserpin-2
, serine (or cysteine) proteinase inhibitor, clade D (heparin cofactor), member 1
, serpin D1