Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
HOMER3 encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. Zusätzlich bieten wir Ihnen HOMER3 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 70 products:
Human Polyclonal HOMER3 Primary Antibody für FACS, IHC (p) - ABIN652274
Norton, Williams, Williams, Spurlock, Zammit, Jones, Jones, Owen, ODonovan, Owen: Mutation screening of the Homer gene family and association analysis in schizophrenia. in American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2003
Show all 2 Pubmed References
Rat (Rattus) Polyclonal HOMER3 Primary Antibody für ICC, IHC - ABIN1742342
Tao-Cheng, Thein, Yang, Reese, Gallant: Homer is concentrated at the postsynaptic density and does not redistribute after acute synaptic stimulation. in Neuroscience 2014
Homer3 acts as a scaffold that spatially organizes actin assembly to support neutrophil polarity and motility downstream of GPCR activation.
Interaction of the protein with amyloid precursor protein (zeige APP Antikörper) is regulated by calcium homeostasis.
Loss of Homer3 is associated with acute myeloid leukemia (zeige BCL11A Antikörper).
Homer3 specifically associates with a novel ubiquitin-like domain in the I kappa B kinase (IKK) beta (zeige IKBKB Antikörper) subunit (zeige POLG Antikörper) of the IKK (zeige CHUK Antikörper) complex.
Homer-3 may be involved in the regulation of SRE activation in T cells via interaction between its EVH1 domain and C/EBP beta (zeige CEBPB Antikörper).
Fat1 (zeige FAT1 Antikörper) exhibit co-localisation with Homer-3 in cellular protrusions and at the plasma membrane of HeLa cells
study found that Homer2 and Homer3 are negative regulators of T cell activation; this is achieved through binding of nuclear factor of activated T cells (NFAT) and by competing with calcineurin
impaired mTORC1-Homer-3 activity underlies PC susceptibility in Spinocerebellar ataxia type 1 and presents a promising therapeutic target
Expression of Homer (zeige HOMER1 Antikörper) 3a/b is restricted to the developing cerebellum, hippocampus, and neonatal olfactory bulb, and is concentrated in the dendritic spines of Purkinje cells and their axons.
Homer2 (zeige HOMER2 Antikörper) and Homer3 proteins interact specifically with amyloid precursor protein (APP (zeige APP Antikörper)) by inhibiting APP (zeige APP Antikörper) processing and reducing secretion of Abeta (zeige APP Antikörper) peptides.
Homer3 in Purkinje cells might function as a reversible coupler regulated by CaMKII (zeige CAMK2G Antikörper) phosphorylation and that the phosphorylation is capable of regulating the postsynaptic molecular architecture in response to synaptic activity.
This gene encodes a member of the HOMER family of postsynaptic density scaffolding proteins that share a similar domain structure consisting of an N-terminal Enabled/vasodilator-stimulated phosphoprotein homology 1 domain which mediates protein-protein interactions, and a carboxy-terminal coiled-coil domain and two leucine zipper motifs that are involved in self-oligomerization. The encoded protein binds numerous other proteins including group I metabotropic glutamate receptors, inositol 1,4,5-trisphosphate receptors and amyloid precursor proteins and has been implicated in diverse biological functions such as neuronal signaling, T-cell activation and trafficking of amyloid beta peptides. Alternative splicing results in multiple transcript variants.
homer protein homolog 3
, Homer, neuronal immediate early gene, 3
, homer homolog 3 (Drosophila)
, homer, neuronal immediate early gene, 3
, VASP/Ena-related gene up-regulated during seizure and LTP 3