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HOXB2 is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. Zusätzlich bieten wir Ihnen HOXB2 Antikörper (45) und HOXB2 Kits (2) und viele weitere Produktgruppen zu diesem Protein an.
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HOXB2 and HOXB3 (zeige HOXB3 Proteine) act as tumor suppressors in acute myeloid leukemia (zeige BCL11A Proteine) patients carrying the FLT3 (zeige FLT3 Proteine) protein mutations.
Increased expression of HOXB2 protein is associated with HPV infection and cervical cancer progression.
HOXB2 acts as a negative tumor growth regulator, decreasing proliferation in mammary adenocarcinoma tumors.
hoxb2 and hoxb4 (zeige HOXB4 Proteine) expression is related to erythroid hematopoiesis, and hoxb4 (zeige HOXB4 Proteine) has greater relevance to erythroid hematopoiesis as compared with hoxb2.
Downregulation of HoxB2, HoxB4 (zeige HOXB4 Proteine) and Alx4 (zeige ALX4 Proteine) expression during the narrow window of early embryogenesis may cause omphalocele in the Cd chick model by interfering with molecular signaling required for proper VBW formation.
Data show that inducible Hox (zeige MSH2 Proteine) genes are selectively sensitive to the inhibition of actin polymerization and that actin polymerization is required for the assembly of a transcription complex on the regulatory region of the Hox (zeige MSH2 Proteine) genes.
Hoxb2 is a direct target for regulation by PLZF (zeige ZBTB16 Proteine) in the developing CNS and suggest that deregulation of Hox (zeige MSH2 Proteine) gene expression may contribute to APL (zeige FASL Proteine) pathogenesis.
HOXB2 up-regulated lesions to have much higher HOXB2 expression than the corresponding normal tissue.
These results establish a role for Hox (zeige MSH2 Proteine) factors in tonotopic refinement of connectivity and in ensuring the precision of sound transmission in the mammalian auditory circuit.
Hoxb2 antagonizes Hoxa2 (zeige HOXA2 Proteine) during rostral hindbrain oligodendrogenesis.
results describe the functional requirements in hindbrain neuronal patterning that follow the establishment of the genetic regulatory hierarchy between Hoxa1 (zeige HOXA1 Proteine), Hoxb1 (zeige HOXB1 Proteine) and Hoxb2
Interaction of HoxB2 with mutant SOD1 (zeige SOD1 Proteine) occurs in motor neurons of G93A mutant SOD1 (zeige SOD1 Proteine) transgenic mice and suggest that this interaction may modulate the neurotoxicity of mutant SOD1 (zeige SOD1 Proteine).
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with pancreatic cancer.
, homeobox protein Hoxb-2
, homeobox protein Hox-B2a
, homeobox gene B-2
, transcription factor Hoxb2
, K8 home protein
, homeo box 2H
, homeo box B2
, homeobox protein Hox-2.8
, homeobox protein Hox-2H
, homeobox protein Hox-B2
, Hoxb2-like epididymal protein