anti-Holocytochrome C Synthase (HCCS) Antikörper

The protein encoded by HCCS is an enzyme that covalently links a heme group to the apoprotein of cytochrome c. Zusätzlich bieten wir Ihnen Holocytochrome C Synthase Kits (16) und Holocytochrome C Synthase Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
HCCS 3052 P53701
HCCS 317444  
HCCS 15159 P53702
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Top anti-Holocytochrome C Synthase Antikörper auf antikoerper-online.de

Showing 10 out of 83 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-HCCS AntibodyTitration: 1.0 µg/mL <br /> Positive Control: HepG2 Whole Cell 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Hund Kaninchen Unkonjugiert WB WB Suggested Anti-HCCS AntibodyTitration: 1.0 µg/mL <br /> Positive Control: U937 Whole Cell 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of HCCS Antibody (Center) (ABIN653839) in WiDr cell line lysates (35 µg/lane). HCCS (arrow) was detected using the purified polyclonal antibody. Western blot analysis of HCCS Antibody (Center) (ABIN653839) in mouse heart tissue lysates (35 µg/lane). HCCS (arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded colon carcinoma reacted with HCCS / CCHL Antibody (Center) followed which was peroxidase conjugated to the secondary antibody and followed by DAB staining. Western blot analysis of HCCS / CCHL Antibody (Center) in mouse heart tissue lysates (35ug/lane). HCCS (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IF, IHC, ELISA, WB Western blot analysis of extracts from HeLa/HepG2/COLO cells, using Cytochrome c-type Heme Lyase Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human tonsil tissue, using Cytochrome c-type Heme Lyase Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Hamster Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: HCCS Antibody [NBP1-86577] - Staining of human cell line U-251MG shows positivity in mitochondria. Western Blot: HCCS Antibody [NBP1-86577] - Lane 1: Marker [kDa] 206, 113, 82, 49, 32, 26, 18.Lane 2: Human cell line RT-4 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$439.69
Details
Human Kaninchen Unkonjugiert ELISA, IF, IHC, WB 100 μL Anmelden zum Anzeigen 16 Days
$175.80
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p) Paraformaldehyde-fixed, paraffin embedded rat brain tissue, Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes, Blocking buffer (normal goat serum) at 37°C for 30min, Antibody incubation with HCCS Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4°C, followed by a conjugated secondary antibody for 20 minutes and DAB staining. 100 μL Anmelden zum Anzeigen 14 bis 21 Tage
$295.90
Details
Human Kaninchen Unkonjugiert IC, IF, IP, IHC, WB Immunofluorescent analysis of HCCS staining in Raw264.7 cells. Formalin-fixed cells were permeabilized with 0.1% Triton X-100 in TBS for 5-10 minutes and blocked with 3% BSA-PBS for 30 minutes at room temperature. Cells were probed with the primary antibody in 3% BSA-PBS and incubated overnight at 4 °C in a humidified chamber. Cells were washed with PBST and incubated with a DyLight 594-conjugated secondary antibody (red) in PBS at room temperature in the dark. DAPI was used to stain the cell nuclei (blue). Immunohistochemical analysis of HCCS staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details

HCCS Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-Holocytochrome C Synthase Antikörper

  1. Human Polyclonal HCCS Primary Antibody für ICC, IF - ABIN4316664 : Thinon, Serwa, Broncel, Brannigan, Brassat, Wright, Heal, Wilkinson, Mann, Tate: Global profiling of co- and post-translationally N-myristoylated proteomes in human cells. in Nature communications 2014 (PubMed)

Weitere Antikörper gegen Holocytochrome C Synthase Interaktionspartner

Human Holocytochrome C Synthase (HCCS) Interaktionspartner

  1. Data suggest that although HCCS mediates heme attachment to N-terminal cysteine in heme-attachment site (CXXXH) of cytochrome C (zeige CYCS Antikörper) variants, up to 50% of cytochrome C (zeige CYCS Antikörper) produced is modified in an oxygen-dependent manner, resulting in a mixed population of cytochrome c (zeige CYCS Antikörper). [HCCS = holocytochrome c synthase]

  2. Bacterial cyt c (zeige CYCS Antikörper) biogenesis pathways (Systems I and II) appear to recognize simply the CXXCH motif, not requiring alpha helix-1. Results here explain mechanistically how HCCS (System III) requires an extended region adjacent to CXXCH for maturation.

  3. cysteines and histidine of the heme attachment site, Cys (zeige DNAJC5 Antikörper)-XX-Cys (zeige DNAJC5 Antikörper)-His play a key role in mitochondrial holocytochrome c synthase

  4. These data indicate that heme contacts mediated by residues within these domains modulate the dynamics of heme binding and contribute to the stability of the HCCS-heme-cytochrome c (zeige CYCS Antikörper) steady state ternary complex.

  5. Identification of a deletion in two patients, including HCCS, leads to the diagnosis of microphthalmia with linear skin defects syndrome

  6. Spectroscopic analyses of HCCS alone and complexes of HCCS with site-directed variants of cytochrome c (zeige CYCS Antikörper) revealed the fundamental steps of heme attachment and maturation.

  7. Through the study of genetically engineered mice, the loss of HCCS is demonstrated to cause the male lethality of microphthalmia with linear skin defects (MLS) syndrome.

  8. mutant proteins (R217C and Delta 197-268) were unable to complement a Saccharomyces cerevisiae mutant deficient for the HCCS orthologue Cyc3p, in contrast to wild-type HCCS

  9. Missense mutation p.E159K of HCCS, leading to loss-of-function of encoded holocytochrome c-type synthase, in female with microphthalmia of both eyes and bilateral sclerocornea may suggest HCCS as candidate for severe ocular manifestations.

Mouse (Murine) Holocytochrome C Synthase (HCCS) Interaktionspartner

  1. Analysis of Mid1 (zeige MID1 Antikörper), Hccs, Arhgap6 (zeige ARHGAP6 Antikörper), and Msl3l1 (zeige MSL3 Antikörper) in X-linked polydactyly (Xpl) and Patchy-fur (Paf (zeige KIAA0101 Antikörper)) mutant mice

Holocytochrome C Synthase (HCCS) Antigen-Profil

Protein Überblick

The protein encoded by this gene is an enzyme that covalently links a heme group to the apoprotein of cytochrome c. Defects in this gene are a cause of microphthalmia syndromic type 7 (MCOPS7). Three transcript variants encoding the same protein have been found for this gene.

Genbezeichner und Symbole assoziert mit HCCS

  • holocytochrome c synthase (hccs) Antikörper
  • cytochrome c heme-lyase (cchl) Antikörper
  • holocytochrome c synthase (HCCS) Antikörper
  • holocytochrome c synthase (Hccs) Antikörper
  • holocytochrome c synthase-like (LOC100356413) Antikörper
  • holocytochrome c synthetase (Hccs) Antikörper
  • CCHL Antikörper
  • DDBDRAFT_0217711 Antikörper
  • DDBDRAFT_0266707 Antikörper
  • DDB_0217711 Antikörper
  • DDB_0266707 Antikörper
  • hccsb Antikörper
  • id:ibd1278 Antikörper
  • MCOPS7 Antikörper
  • RGD1563855 Antikörper
  • wu:fb18h01 Antikörper
  • wu:fc64e12 Antikörper
  • wu:fi43e01 Antikörper

Bezeichner auf Proteinebene für HCCS

cytochrome c-type heme lyase , holocytochrome c synthetase b , holocytochrome c synthase (cytochrome c heme-lyase) , holocytochrome c synthase , cytochrome c heme-lyase , holocytochrome c-type synthase , holocytochrome c synthetase , CCHL

GENE ID SPEZIES
58016 Danio rerio
448226 Xenopus (Silurana) tropicalis
8620147 Dictyostelium discoideum AX4
3052 Homo sapiens
317444 Rattus norvegicus
506250 Bos taurus
424482 Gallus gallus
480834 Canis lupus familiaris
100356413 Oryctolagus cuniculus
15159 Mus musculus
Ausgewählte Anbieter für anti-Holocytochrome C Synthase (HCCS) Antikörper
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