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HDAC11 encodes a class IV histone deacetylase. Zusätzlich bieten wir Ihnen Histone Deacetylase 11 Antikörper (119) und Histone Deacetylase 11 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.
Overexpressing any of HDAC 3, 6, or 11 suppresses CGG repeat-induced neurodegeneration in a Drosophila model of fragile X tremor ataxia syndrome.
High HDAC11 expression is associated with neoplasms.
Data indicate a pronounced deregulation of HDAC (zeige HDAC3 ELISA Kits) genes HDAC9 (zeige HDAC9 ELISA Kits) and HDAC11 in patients with Philadelphia-negative chronic myeloproliferative neoplasms: essential thrombocythemia (ET), polycythemia vera (zeige IGF2BP3 ELISA Kits) (PV) and primary myelofibrosis (PMF (zeige PRB1 ELISA Kits)).
These results demonstrate for the first time that HDAC11 plays an essential role in regulating OX40L (zeige TNFSF4 ELISA Kits) expression.
HDAC11 associates with replication origins inhibits Cdt1 (zeige CDT1 ELISA Kits)-induced re-replication and suppresses MCM loading.
We found a reduction of HDAC 11 mRNA and increased HDAC 2 (zeige HDAC2 ELISA Kits) levels in amyotrophic lateral sclerosis brain and spinal cord compared with controls.
Fluorescence in situ hybridization analysis localized HDAC11 gene to chromosome 3p25, a region characterized by frequent gains and losses of chromosomal material in a number of various types of cancer.
the absence of tumour-specific somatic events in WNT7A (zeige WNT7A ELISA Kits) and HDAC11 suggests that these genes are unlikely to have a classical tumour suppressor gene role in sporadic malignant pancreatic endocrine tumours
HDAC11 negatively regulated expression of the gene encoding interleukin 10 (zeige IL10 ELISA Kits) in antigen-presenting cells.
Cdt1 (zeige CDT1 ELISA Kits) undergoes acetylation and is reversibly deacetylated by HDAC11
we have been able to demonstrate a lineage-restricted overexpression of HDAC11 in neutrophils and committed neutrophil precursors and it appears to associate with the transcription machinery, possibly regulating the expression of inflammatory and migratory genes in neutrophils. Our results highlight a unique and novel role for HDAC11
our results indicate that the alcohol-induced responsiveness of Kupffer cells to gut (zeige GUSB ELISA Kits)-derived endotoxin, in part, is governed by miR (zeige MLXIP ELISA Kits)-155 and HDAC11
HDAC11-knockout T cells displayed enhanced proliferation, proinflammatory cytokine production, and effector molecule expression of Eomes and TBX21 transcription factors previously shown to regulate inflammatory cytokine and effector molecule production.
HDAC11 appears to function as a negative regulator of myeloid-derived suppressor cells expansion/function in vivo.
HDAC6 (zeige HDAC6 ELISA Kits), primarily a cytoplasmic protein, associates with HDAC11 and modulates the expression of IL-10 (zeige IL10 ELISA Kits) as a transcriptional activator.
The HDAC11 transcript is a PDGF (zeige PDGFA ELISA Kits) target; the HDAC11 mRNA abundance correlates inversely with proliferative status.
Male gender and male hormones accelerate kidney ischemia reperfusion-induced decreases in expression and binding of HDAC11, resulting in an increase in PAI-1 (zeige SERPINE1 ELISA Kits) expression.
Role for HDAC11 in central nervous system histone deacetylation and the development of oligodendrocytes and neurons during postnatal development.
This gene encodes a class IV histone deacetylase. The encoded protein is localized to the nucleus and may be involved in regulating the expression of interleukin 10. Alternative splicing results in multiple transcript variants.
, histone deacetylase X
, histone deacetylase 11