anti-Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) Antikörper

HNRNPU belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). Zusätzlich bieten wir Ihnen Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) Kits (26) und Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
HNRNPU 51810 Q8VEK3
HNRNPU 117280  
HNRNPU 3192 Q00839
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Top anti-Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) Antikörper auf antikoerper-online.de

Showing 10 out of 61 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-HNRNPU Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>MCF7 cell lysate 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-HNRNPU Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>ACHN cell lysate WB Suggested Anti-HNRNPU <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500 <br /> Positive Control: ACHN cell lysate <br /> HNRNPU is strongly supported by BioGPS gene expression data to be expressed in Human ACHN cells 100 μL Anmelden zum Anzeigen 6 bis 8 Tage
358,51 €
Details
Human Kaninchen Unkonjugiert IHC (p), IHC, WB Western Blot: hnRNP U Antibody [ABIN151573] - Detection of Human and Mouse hnRNP-U on HeLa whole cell lysate using ABIN151573. 0.1 mL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
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Human Kaninchen Unkonjugiert IP, WB 100 μL Anmelden zum Anzeigen 2 bis 4 Tage
371,00 €
Details
Huhn Maus Unkonjugiert IF, IP, IHC, WB Western blot analysis of p120 Catenin on a A431 cell lysate (Human epithelial carcinoma, ATCC CRL-1555). Lane 1: 1:1000, lane 2: 1:2000, lane 3: 1:4000 dilution of the mouse anti-p120 Catenin antibody. Immunofluorescence staining of human fibroblasts. 50 μg Anmelden zum Anzeigen 2 bis 4 Tage
146,73 €
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Maus Maus Unkonjugiert ChIP, ELISA, FACS, ICC, IF, IHC (p), IP, WB Western blot showing Anti-hnRNP-U on HeLa cell extracts 50 μL Anmelden zum Anzeigen 3 bis 4 Tage
385,00 €
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Maus Kaninchen Unkonjugiert IC, IF, IP, WB 100 μL Anmelden zum Anzeigen 5 bis 7 Tage
398,10 €
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Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
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Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
653,02 €
Details
Human Kaninchen Unkonjugiert IHC, IP, WB 100 μL Anmelden zum Anzeigen 12 Days
392,86 €
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HNRNPU Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) Antikörper

  1. Mouse (Murine) Monoclonal HNRNPU Primary Antibody für ChIP, ELISA - ABIN108577 : Dreyfuss, Choi, Adam: Characterization of heterogeneous nuclear RNA-protein complexes in vivo with monoclonal antibodies. in Molecular and cellular biology 1984 (PubMed)
    Show all 8 Pubmed References

  2. Mouse (Murine) Monoclonal HNRNPU Primary Antibody für ChIP, ELISA - ABIN108578 : Ahmad, Lingrel: Kruppel-like factor 2 transcriptional regulation involves heterogeneous nuclear ribonucleoproteins and acetyltransferases. in Biochemistry 2005 (PubMed)
    Show all 8 Pubmed References

  3. Chicken Monoclonal HNRNPU Primary Antibody für IF, IP - ABIN967770 : Eger, Stockinger, Schaffhauser, Beug, Foisner: Epithelial mesenchymal transition by c-Fos estrogen receptor activation involves nuclear translocation of beta-catenin and upregulation of beta-catenin/lymphoid enhancer binding factor-1 transcriptional activity. in The Journal of cell biology 2000 (PubMed)
    Show all 5 Pubmed References

  4. Mouse (Murine) Polyclonal HNRNPU Primary Antibody für IC, IF - ABIN2452032 : Kiledjian, Dreyfuss: Primary structure and binding activity of the hnRNP U protein: binding RNA through RGG box. in The EMBO journal 1992 (PubMed)
    Show all 2 Pubmed References

  5. Human Polyclonal HNRNPU Primary Antibody für IHC (p), IHC - ABIN151573 : Banerjee, Mandal, Das, Hegde, Das, Bhakat, Boldogh, Sarkar, Mitra, Hazra: Preferential repair of oxidized base damage in the transcribed genes of mammalian cells. in The Journal of biological chemistry 2011 (PubMed)

  6. Human Polyclonal HNRNPU Primary Antibody für IP, WB - ABIN151574 : Powell, Coulson, Crary, Wong, Ach, Tsang, Alice Yamada, Yasui, Lasalle: A Prader-Willi locus lncRNA cloud modulates diurnal genes and energy expenditure. in Human molecular genetics 2013 (PubMed)

Weitere Antikörper gegen Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) Interaktionspartner

Mouse (Murine) Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) Interaktionspartner

  1. findings provide conclusive evidence for the essential role of hnRNP U in heart development and function and in the regulation of alternative splicing.

  2. SAF-A interacts with BRG1 and both components are required for RNA Polymerase II Mediated Transcription

  3. Macrophage expression of hnRNP U was induced by TLR stimulation. hnRNP U knockdown attenuated & overexpression increased TLR-induced expression of TNF-alpha (zeige TNF Antikörper), IL-6 (zeige IL6 Antikörper) & IL-1beta (zeige IL1B Antikörper). hnRNP U bound to the mRNA of these cytokines via the RGG motif.

  4. Data report that endogenous SAF-A is involved in regulation of Oct4 (zeige POU5F1 Antikörper) expression, binds the Oct4 (zeige POU5F1 Antikörper) proximal promoter in ES cells, and dissociates from the promoter upon early differentiation induced by LIF (zeige LIF Antikörper) withdrawal.

  5. hnRNP-U engages a highly neddylated active SCF (zeige KITLG Antikörper) beta-TrCP (zeige BTRC Antikörper) which dissociates in the presence of a high-affinity substrate, resulting in the ubiquitination of the latter.

  6. hnRNP U participates in nuclear regulatory events that are involved in mammalian central and peripheral circadian clocks.

  7. nuclear matrix protein SAF-A binds to the 3'-flanking region of the Bmal1 (zeige ARNTL Antikörper) gene with circadian timing

  8. HnRNP U binding to the 5'-UTR (zeige UTS2R Antikörper) of the Shh (zeige SHH Antikörper) facilitates gene expression during limb development.

  9. SAF-A was found to be localized in three different domains: outside the chromosomes, on the surface of the chromosome arms, and in the centromere region where it apparently binds specifically to the satellite DNA.

  10. the c-Myc (zeige MYC Antikörper)-Max complex exerts its transcriptional regulatory role and hnRNP U may be a coactivator of this transcriptional activator complex.

Human Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) Interaktionspartner

  1. We broaden the clinical and mutational HNRNPU-associated spectrum, and demonstrate that heterozygous HNRNPU variants cause epilepsy, severe intellectual disability with striking speech impairment and variable central nervous system, cardiac, and renal anomalies.

  2. Results show that SAF-A and caRNAs form a dynamic, transcriptionally responsive chromatin mesh that organizes large-scale chromosome structures and protects the genome from instability.

  3. results confirm and refine the complex genotype-phenotype correlations existing in the 1qter microdeletion syndrome and define more precisely the neurodevelopmental phenotypes associated with genetic alterations of AKT3 (zeige AKT3 Antikörper), ZBTB18 (zeige ZNF238 Antikörper) and HNRNPU in humans

  4. mutual regulatory mechanisms exist between PP4 (zeige ANXA5 Antikörper) and SAF-A. Interactions between PP4 (zeige ANXA5 Antikörper) and SAF-A played a role in prometaphase/metaphase transition.

  5. CENP-W (zeige CENPW Antikörper) interacts with hnRNPU and may contribute to kinetochore-microtubule attachment in mitotic cells.

  6. Nuclear TDP-43 (zeige TARDBP Antikörper) becomes neurotoxic by escaping from the inhibitory regulation by hnRNP-U or hnRNP (zeige HNRNPC Antikörper)-A2. hnRNP-U inhibits TDP-43 (zeige TARDBP Antikörper)-mediated alterations in splicing of POLDIP3 (zeige POLDIP3 Antikörper) mRNA.

  7. These results suggest that HNRNPU, FAM36A, and NCRNA00201 are not major genes for microcephaly and corpus callosum abnormalities but are good candidates for intellectual disability (ID) and seizures.

  8. both phosphorylation and dephosphorylation of SAF-A serine 59 by PLK1 (zeige PLK1 Antikörper) and PP2A (zeige PPP2R4 Antikörper), respectively, are required for accurate and timely exit from mitosis.

  9. demonstrate that H19 inhibits RNA Pol II-mediated transcription by disrupting the hnRNP U-actin complex

  10. Induction of caspase (zeige CASP3 Antikörper)-9b expression is due to activation of hnRNP L (zeige HNRNPL Antikörper) via phosphorylation to compete/inhibit hnRNP U association with exon 3 of Casp9 (zeige CASP9 Antikörper) mRNA.

Heterogeneous Nuclear Ribonucleoprotein U (Scaffold Attachment Factor A) (HNRNPU) Antigen-Profil

Protein Überblick

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they form complexes with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene contains a RNA binding domain and scaffold-associated region (SAR)-specific bipartite DNA-binding domain. This protein is also thought to be involved in the packaging of hnRNA into large ribonucleoprotein complexes. During apoptosis, this protein is cleaved in a caspase-dependent way. Cleavage occurs at the SALD site, resulting in a loss of DNA-binding activity and a concomitant detachment of this protein from nuclear structural sites. But this cleavage does not affect the function of the encoded protein in RNA metabolism. At least two alternatively spliced transcript variants have been identified for this gene.

Genbezeichner und Symbole assoziert mit HNRNPU

  • heterogeneous nuclear ribonucleoprotein U (Hnrnpu) Antikörper
  • heterogeneous nuclear ribonucleoprotein U (LOC100348766) Antikörper
  • heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) (HNRNPU) Antikörper
  • heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) (hnrnpu) Antikörper
  • heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) (Hnrnpu) Antikörper
  • AA408410 Antikörper
  • AI256620 Antikörper
  • AL024194 Antikörper
  • AL024437 Antikörper
  • AW557595 Antikörper
  • C86794 Antikörper
  • hnRNP U Antikörper
  • HNRPU Antikörper
  • saf-a Antikörper
  • SAFA Antikörper
  • SN1 Antikörper
  • Sp120 Antikörper
  • U21.1 Antikörper

Bezeichner auf Proteinebene für HNRNPU

SAF-A , heterogenous nuclear ribonucleoprotein U , nuclear matrix protein sp120 , scaffold attachment factor A , system N1 Na+ and H+-coupled glutamine transporter , transporter protein , transporter protein; system N1 Na+ and H+-coupled glutamine transporter , heterogeneous nuclear ribonucleoprotein U , p120 nuclear protein , pp120

GENE ID SPEZIES
51810 Mus musculus
117280 Rattus norvegicus
100348766 Oryctolagus cuniculus
3192 Homo sapiens
399374 Xenopus laevis
539950 Bos taurus
100515571 Sus scrofa
421492 Gallus gallus
100725944 Cavia porcellus
101107118 Ovis aries
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