Hemoglobin beta Proteine (HBB)

The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. Zusätzlich bieten wir Ihnen Hemoglobin Subunit beta Antikörper (81) und Hemoglobin Subunit beta Kits (26) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Human HBB HBB 3043 P68871
Ratte HBB HBB 24440 P02091
Maus HBB HBB 15129  
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Showing 10 out of 201 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
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HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
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HOST_Escherichia coli (E. coli) Human His-SUMO Tag   50 μg Anmelden zum Anzeigen 15 bis 16 Tage
324,76 €
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HOST_Escherichia coli (E. coli) Huhn His tag,S tag 100 μg Anmelden zum Anzeigen 13 bis 17 Tage
380,95 €
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Hefe Primate His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
1.896,19 €
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Hefe Dasyurus viverrinus His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.032,38 €
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Hefe Lithobates catesbeiana His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.189,52 €
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Hefe Rana esculenta His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.189,52 €
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Hefe Heterodontus portusjacksoni His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.193,02 €
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Hefe REACT_Dogfish His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.196,50 €
Details

HBB Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
, , ,
Rat (Rattus)

Mouse (Murine)

Weitere Proteine zu Hemoglobin beta (HBB) Interaktionspartnern

Chimpanzee Hemoglobin beta (HBB) Interaktionspartner

  1. Pan troglodytes and Pongo pygmaeus were screened for mutations in the beta-globin gene (exons 1, 2, and 3) for suspected thalassemia.

  2. We found no evidence of the major deleterious mutations at HBB in chimpanzees that confer resistance to malaria caused by Plasmodium falciparum nor evidence of long-term balancing selection at these loci.

Cow (Bovine) Hemoglobin beta (HBB) Interaktionspartner

  1. Data indicate that on incubating hemoglobin with glyoxal for 0-20 days, advanced glycation end products (AGEs) were detected on day 20.

Pig (Porcine) Hemoglobin beta (HBB) Interaktionspartner

  1. In this study, hemoglobin subunit beta was identified as a classical swine fever virus capsid protein-binding protein by glutathione S-transferase (zeige GSTa2 Proteine) pulldown and subsequent mass spectrometry analysis of PK-15 cells.

Horse (Equine) Hemoglobin beta (HBB) Interaktionspartner

Human Hemoglobin beta (HBB) Interaktionspartner

  1. NF-E2, TAL1 and KLF1, all activators play a primary role in HSs formation in the LCR

  2. Five different beta-globin haplotypes were linked to sickle hemoglobin alleles in Mazandaran province.

  3. 2 cases of Polish patients with hereditary hemolytic anemia suspected of thalassemia were studied; identified 2 different frameshift mutations positioned in the third exon of HBB; results show a lack of natural stop codon due to the frameshift in exon 3 of beta-globin gene causes rapid degradation of its mRNA and indicate existence of novel surveillance pathway

  4. Our work suggested a novel function for HBB as a theranostic molecule: an innate antimetastasis factor with potential utility as an anticancer drug and a biomarker signaling the presence of clinically undetectable metastasis

  5. we concluded that this novel beta-globin gene mutation was associated with the mild phenotype of beta-thal.

  6. We first report a novel beta chain variant, Hb Heze [beta144(HC1)Lys-->Arg; HBB: c.434A>G], in a Chinese family. Heterozygous inheritance of the mutation results in a mild beta-thalassemia (beta-thal) phenotype, whereas compound heterozygosity of Hb Heze with beta(0)-thal appears as the cause of beta-thal intermedia (beta-TI) in our case.

  7. the Fe-His bond of the beta subunits at alkaline pH causes a substantial increase in the change in global structure upon binding of CO to the beta subunit (zeige POLG Proteine)

  8. We screened for b-thalassemia-causing mutations by direct sequencing in different districts of West Bengal. Mutation detection was done using Sanger sequencing of the HBB gene. Results: A total of 14 different mutations were observed, including rare mutations IVS1-130(G>C), IVS1-129(A>C), -90(T>C), CD16 (zeige CD16 Proteine)(-C), -30(T>C), CD15 (zeige FUT4 Proteine)(-T), and a novel mutation CD53 (zeige CD53 Proteine)(C>T).

  9. A report on the frequency and spectrum of beta globin gene mutations in thalassemia patients in a Pakistani population.

  10. Data indicate that binding of hemoblobin (Hb) to glycoprotein1balpha (GP1balpha) induced platelet activation plays a crucial role in thrombus formation on immobilized von Willebrand factor (VWF (zeige VWF Proteine)) or type I collagen under shear stresses.

Mouse (Murine) Hemoglobin beta (HBB) Interaktionspartner

  1. In hemizygous beta-globin knockout (BKO) mice, the duodenal calcium transport was lower than that in wild-type littermates, and severity was especially pronounced in female mice.

  2. The study analyzed protein-DNA interactions in the murine beta-globin gene locus.

  3. Data suggest that beta-globin promoters in general do not exert any appreciable nonlocal effects on chromatin structure.

  4. HIRA (zeige HIRA Proteine) is not only critical for beta-globin expression but is also required for activation of the erythropoietic regulators EKLF (zeige KLF1 Proteine) and GATA binding protein 1 (GATA1).

  5. results revealed iron deficiency induced expression changes in two genes which have never before been implicated in an iron-dopamine pathway, Cxcl12 and hemoglobin, beta adult chain

  6. Data indicate that Myb and BCL11A cooperate with DNMT1 to achieve developmental repression of embryonic and fetal beta-like human transgenic globin genes in the adult erythroid environment.

  7. Dynamic changes in chromatin structure of the beta-globin locus, were examined.

  8. GATA1 (zeige GATA1 Proteine)-HS2 enhancer allows persistent and position-independent expression of a beta (zeige SUCLA2 Proteine)-globin transgene

  9. The limiting effect on RNA levels occurs after beta-globin genes associate with transcription factories, at which time hypersensitivity sites contribute to the RNA arising from each burst of transcription by stimulating transcriptional elongation.

  10. cerebral microvasculature is rendered vulnerable to thrombus formation in beta(s) mice via a neutrophil-dependent mechanism that is associated with an increased formation of and enhanced platelet sensitivity to thrombin (zeige F2 Proteine)

Orang-Utan Hemoglobin beta (HBB) Interaktionspartner

  1. Pan troglodytes and Pongo pygmaeus were screened for mutations in the beta-globin gene (exons 1, 2, and 3) for suspected thalassemia.

Hemoglobin Subunit beta (HBB) Protein Überblick

Protein Überblick

The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Genbezeichner und Symbole assoziert mit Hemoglobin beta Proteine (HBB)

  • hemoglobin, beta (HBB)
  • hemoglobin, gamma G (HBG2)
  • hemoglobin, epsilon 1 (HBE1)
  • hemoglobin, beta (HBB2)
  • hemoglobin, beta (HBE)
  • hemoglobin beta (HBB)
  • hemoglobin subunit beta-like (LOC100720944)
  • hemoglobin subunit beta-like (LOC480784)
  • hemoglobin, beta (Hbb)
  • hemoglobin, beta adult major chain (Hbb-b1)
  • hemoglobin subunit beta-like (LOC100438527)
  • beta globin (LOC100136576)
  • hemoglobin beta chain complex (Hbb)
  • keratin 123 pseudogene (KRT123P)
  • AA409645 Protein
  • beta-globin Protein
  • beta1 Protein
  • CD113t-C Protein
  • hbb Protein
  • Hbb1 Protein
  • HBBA Protein
  • HBBB Protein
  • Hbbt1 Protein
  • Hbbt2 Protein
  • HBD Protein
  • HBE1 Protein
  • HBG1 Protein
  • HBG2 Protein
  • KRTHBP2 Protein
  • MommeD7 Protein

Bezeichner auf Proteinebene für Hemoglobin beta Proteine (HBB)

hemoglobin, beta , beta-globin , hemoglobin beta chain , hemoglobin subunit beta , beta-A globin , hemoglobin, delta , hemoglobin, epsilon 1 , epsilon globin , beta-H globin , hemoglobin, gamma A , beta globin , beta-1/2-globin , hemoglobin beta-1/2 chain , hemoglobin subunit beta-1/2 , epsilon-globin , hemoglobin epsilon chain , hemoglobin subunit epsilon , hemoglobin, gamma G , Beta-globin , Hemoglobin beta chain , globin, beta , hemoglobin beta , beta globin chain , III beta-1 globin , III beta-2 globin , beta-1-globin , hemoglobin beta chain complex , hemoglobin beta chain, major-form , hemoglobin beta-1 chain , hemoglobin subunit beta-1 , beta maj , beta major globin

GENE ID SPEZIES
100137310 Papio anubis
450978 Pan troglodytes
396485 Gallus gallus
428114 Gallus gallus
100009084 Oryctolagus cuniculus
280813 Bos taurus
428115 Gallus gallus
407066 Sus scrofa
100049064 Ovis aries
100054109 Equus caballus
100499573 Ailuropoda melanoleuca
100720944 Cavia porcellus
3043 Homo sapiens
480784 Canis lupus familiaris
715559 Macaca mulatta
24440 Rattus norvegicus
15129 Mus musculus
100438527 Pongo abelii
100136576 Salmo salar
15127 Mus musculus
85344 Homo sapiens
101098159 Felis catus
100976465 Pan paniscus
100410611 Callithrix jacchus
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