Hemoglobin, gamma A Proteine (HBG1)

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Zusätzlich bieten wir Ihnen HBG1 Antikörper (39) und HBG1 Kits (9) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
Ratte HBG1 HBG1 94164  
HBG1 3047 P69891
HBG1    
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Top HBG1 Proteine auf antikoerper-online.de

Showing 9 out of 12 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 26 bis 31 Tage
4.115,41 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
Details
Hefe Pan paniscus His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.206,98 €
Details
Hefe Pan troglodytes His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.206,98 €
Details
Hefe Pongo pygmaeus His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.206,98 €
Details
Hefe Primate His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.206,98 €
Details
Hefe REACT_Titi monkey His tag   1 mg Anmelden zum Anzeigen 58 bis 70 Tage
2.206,98 €
Details
HOST_Escherichia coli (E. coli) Human Unkonjugiert   50 μg Anmelden zum Anzeigen 6 bis 8 Tage
484,01 €
Details

HBG1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Primate (Cebus)

Weitere Proteine zu Hemoglobin, gamma A (HBG1) Interaktionspartnern

Human Hemoglobin, gamma A (HBG1) Interaktionspartner

  1. Introduction of the British HPFH mutation into the fetal globin promoter in a human cell model causes elevated fetal globin expression. The British HPFH mutation creates a de novo binding site both in vitro and in vivo for the potent erythroid activator KLF1 (zeige KLF1 Proteine).

  2. A Ly1 antibody reactive (LYAR)-binding motif disruptive regulatory single-nucleotide polymorphisms rs368698783 (G/A) from LD block 5 in the proximal promoter of hemoglobin subunit gamma 1 (HBG1) was found to be a significant predictor for beta-thalassemia clinical severity.

  3. Study found a novel polymorphism of the A-gamma-globin gene in four families with b0-thalassemia and high levels of HbF expression. Additionally, evidence suggesting that the Ac-globin gene +25(G-A) polymorphism decreases the efficiency of the interaction between this sequence and specific DNA binding protein (zeige UBE2V1 Proteine) complexes.

  4. These data confirm the regulatory role of the HBG1: g.-225_-222 region that exerts its effect under conditions of erythropoietic stress characteristic for beta-thal patients.

  5. results suggest that KLF1 directly regulates the beta-globin gene, but probably has less direct impact on expression of the gamma-globin gene in fetal erythroblasts

  6. Data show that the ancestral allele C at rs2855126, located upstream of gamma-globin (HBG1) is associated with increased serum uric acid levels.

  7. analysis of a point mutation that increases fetal globin expression through de novo recruitment of the activator TAL1 to promote chromatin looping of distal enhancers to the modified gamma-globin promoter

  8. a successful induction of gamma-globin includes a reduction in BCL11A (zeige BCL11A Proteine), KLF1 (zeige KLF1 Proteine) and TAL1 (zeige TAL1 Proteine) expression.

  9. This report we discusses the molecular characteristics and diagnostic criteria of a new (A)gamma chain variant that was detected during newborn screening and named Hb F-Sykesville MD [(A)gamma113(G15 (zeige RBM5 Proteine))Val --> Ile; HBG1: c.340G>A].

  10. Results indicate that compound II induces the gamma globin gene in hydroxyurea (HU)-resistant primary adult erythroid cells and suggest potenetial therapy for sickle cell disease (SCD (zeige SCD Proteine)) and severe beta-thalassemias.

HBG1 Protein Überblick

Protein Überblick

The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'.

Genbezeichner und Symbole assoziert mit Hemoglobin, gamma A Proteine (HBG1)

  • hemoglobin subunit gamma-1-like (LOC100438895)
  • hemoglobin, gamma A (Hbg1)
  • hemoglobin, gamma A (HBG1)
  • hemoglobin, gamma G (HBG2)
  • Hbb-y Protein
  • Hbe1 Protein
  • HBG1 Protein
  • HBG2 Protein
  • HBGA Protein
  • HBGR Protein
  • HSGGL1 Protein

Bezeichner auf Proteinebene für Hemoglobin, gamma A Proteine (HBG1)

epsilon 3 globin , hemoglobin Y beta-like embryonic chain , hemoglobin Y, beta-like embryonic chain , hemoglobin, epsilon 1 , hemoglobin, gamma A , A-gamma globin , gamma A hemoglobin , gamma globin , gamma-1-globin , hb F Agamma , hemoglobin gamma-1 chain , hemoglobin gamma-a chain , hemoglobin subunit gamma-1 , hemoglobin, gamma, regulator of , epsilon-globin , hemoglobin, gamma G

GENE ID SPEZIES
100438895 Pongo abelii
94164 Rattus norvegicus
100137314 Papio anubis
3047 Homo sapiens
450979 Pan troglodytes
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