Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
HHEX encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Zusätzlich bieten wir Ihnen Hematopoietically Expressed Homeobox Antikörper (128) und Hematopoietically Expressed Homeobox Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.
Data show that knockdown of hematopoietically expressed homeobox (hhex) resulted in a down-regulation of ventral pancreatic precursor 1 (vpp1 (zeige ATP6V0A1 ELISA Kits)) expression and a specific loss of the ventral pancreas.
A gene regulatory network controlling hhex transcription in the anterior endoderm of the organizer.
HHEX over expression induced by human cytomegalovirus infection closely associated with vascular proliferative diseases.
The multivariate logistic regression analysis with reference to both alleles and genotypes of CDKAL1 (zeige CDKAL1 ELISA Kits) SNPs showed significant association, suggesting an important role for this gene in the T2DM pathophysiology. INTERPRETATION & CONCLUSIONS: A significant association was seen of all the three SNPs of CDKAL1 (zeige CDKAL1 ELISA Kits) and CDKN2A/B genes with T2DM but none of the two SNPs of HHEX.
These studies identify uPA (zeige PRAP1 ELISA Kits)-dependent de-repression of vegfr1 (zeige FLT1 ELISA Kits) and vegfr2 (zeige KDR ELISA Kits) gene transcription through binding to HHEX/PRH as a novel mechanism by which uPA (zeige PRAP1 ELISA Kits) mediates the pro-angiogenic effects of VEGF (zeige VEGFA ELISA Kits) and identifies a potential new target for control of pathologic angiogenesis.
Low HHEX mutation is associated with Thyroid Dysgenesis.
Data suggest that hematopoietically expressed homeobox protein (HHEX) downmodulation by promyelocytic leukemia (zeige PML ELISA Kits)-retinoic acid receptor alpha (zeige RARA ELISA Kits) fusion oncoprotein (PML (zeige PML ELISA Kits)-RARalpha (zeige RARA ELISA Kits)) is a key event during acute promyelocytic leukemia (zeige PML ELISA Kits) (APL (zeige FASL ELISA Kits)) pathogenesis.
Hhex binds to the Cdkn2a locus and directly interacts with the Polycomb (zeige CBX2 ELISA Kits)-repressive complex 2 (PRC2) to enable H3K27me3-mediated epigenetic repression
Data suggest that Hhex is a novel regulator of c-Myc (zeige MYC ELISA Kits) function that limits c-Myc (zeige MYC ELISA Kits) activity in transformed cells.
PRH controls the migration of multiple epithelial cell lineages in part at least through the direct transcriptional regulation of Endoglin (zeige ENG ELISA Kits)
HHEX promotes hepatic specification by repressing EOMES (zeige EOMES ELISA Kits) expression.
Data indicate the potential importance of CDKAL1 (zeige CDKAL1 ELISA Kits) protein and homeobox protein HHEX in glucose homeostasis in this Alaska Native population with a low prevalence of type 2 diabetes (T2D).
The Hhex evolutionarily conserved non-coding region appears to be a core node for the convergence of the transcription factor network that governs the emergence of Hematopoietic stem cells.
Hhex(-/-) mESCs fail to differentiate from definitive endoderm to hepatic endoderm.
results implicate Hhex in the maintenance of LT-HSCs and in lineage allocation from multipotent progenitors especially in stress hematopoiesis.
Hhex regulates Kit to promote radioresistance of self-renewing thymocytes in Lmo2 (zeige LMO2 ELISA Kits)-transgenic mice.
Hhex is a key regulator of early lymphoid development, functioning, at least in part, via regulation of the cell cycle.
Hhex and Cer1 (zeige CER1 ELISA Kits) are indispensable components of the Sox17 (zeige SOX17 ELISA Kits) pathway for cardiopoiesis.
Hhex as the first transcriptional regulator specifically required for islet delta cells and suggest compromised paracrine control as a contributor to T2DM
Data suggest that GPC3 (zeige GPC3 ELISA Kits) down-regulates hepatocyte proliferation by binding to hedgehog (zeige SHH ELISA Kits) (HH) and down-regulating the HH signaling pathway and binding with CD81 (zeige CD81 ELISA Kits), thus making it unavailable to bind to Hhex and causing its nuclear translocation.
Hex expression and subcellular localization are associated with chondrocyte maturation
hhex, nk2.1a, and pax2.1 regulate thyroid growth and differentiation downstream of Nodal-dependent transcription factors.
Data suggest that zebrafish hhex appears to be activated by Wnt (zeige WNT2 ELISA Kits)/beta-catenin (zeige CTNNB1 ELISA Kits) in the dorsal yolk syncytial layer, where bozozok acts in a permissive way to limit repression of hhex by Vega1 and Vega2.
This gene encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation.
Homeobox protein PRH
, hematopoietically-expressed homeobox protein hhex
, homeobox protein hex
, homeodomain transcription factor
, hematopoietically expressed homeobox
, hematopoietically-expressed homeobox protein HHEX
, homeobox protein HEX
, homeobox protein PRH
, homeobox, hematopoietically expressed
, proline-rich homeodomain-containing transcription factor
, hematopoietically expressed homeobox protein
, hematopoietically expressed homeobox, related sequence 2
, hematopoietically-expressed homeobox protein Hhex