anti-Hematopoietically Expressed Homeobox (HHEX) Antikörper

HHEX encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Zusätzlich bieten wir Ihnen Hematopoietically Expressed Homeobox Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
HHEX 3087 Q03014
HHEX 15242 P43120
HHEX 79237  
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Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB Human Muscle Rabbit Anti-HHEX Antibody  Catalog Number: ARP31443_P050 Formalin Fixed Paraffin Embedded Tissue: Human Adult heart  Observed Staining: Nuclei in adipocytes but not in cardiomyocytes Primary Antibody Concentration: 1:100 Secondary Antibody: Donkey anti-Rabbit-Cy2/3 Secondary Antibody Concentration: 1:200 Magnification: 20X Exposure Time: 0.5 – 2.0 sec Protocol located in Reviews and Data. 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-HHEX Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>293T cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
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Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-Hhex Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:62500 Positive Control: Mouse Muscle 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Hund Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
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Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
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Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Hund Kaninchen Unkonjugiert IHC (p), ELISA Human Breast (formalin-fixed, paraffin-embedded) stained with HHEX antibody ABIN364468 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$595.83
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Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$200.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Meerschweinchen Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details

HHEX Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Hematopoietically Expressed Homeobox Antikörper

  1. Human Polyclonal HHEX Primary Antibody für WB - ABIN966283 : Hromas, Radich, Collins: PCR cloning of an orphan homeobox gene (PRH) preferentially expressed in myeloid and liver cells. in Biochemical and biophysical research communications 1993 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen Hematopoietically Expressed Homeobox Interaktionspartner

Xenopus laevis Hematopoietically Expressed Homeobox (HHEX) Interaktionspartner

  1. Data show that knockdown of hematopoietically expressed homeobox (hhex) resulted in a down-regulation of ventral pancreatic precursor 1 (vpp1 (zeige ATP6V0A1 Antikörper)) expression and a specific loss of the ventral pancreas.

  2. A gene regulatory network controlling hhex transcription in the anterior endoderm of the organizer.

Human Hematopoietically Expressed Homeobox (HHEX) Interaktionspartner

  1. HHEX over expression induced by human cytomegalovirus infection closely associated with vascular proliferative diseases.

  2. The multivariate logistic regression analysis with reference to both alleles and genotypes of CDKAL1 (zeige CDKAL1 Antikörper) SNPs showed significant association, suggesting an important role for this gene in the T2DM pathophysiology. INTERPRETATION & CONCLUSIONS: A significant association was seen of all the three SNPs of CDKAL1 (zeige CDKAL1 Antikörper) and CDKN2A (zeige CDKN2A Antikörper)/B genes with T2DM but none of the two SNPs of HHEX.

  3. These studies identify uPA (zeige PRAP1 Antikörper)-dependent de-repression of vegfr1 (zeige FLT1 Antikörper) and vegfr2 (zeige KDR Antikörper) gene transcription through binding to HHEX/PRH as a novel mechanism by which uPA (zeige PRAP1 Antikörper) mediates the pro-angiogenic effects of VEGF (zeige VEGFA Antikörper) and identifies a potential new target for control of pathologic angiogenesis.

  4. Low HHEX mutation is associated with Thyroid Dysgenesis.

  5. Data suggest that hematopoietically expressed homeobox protein (HHEX) downmodulation by promyelocytic leukemia (zeige PML Antikörper)-retinoic acid receptor alpha (zeige RARA Antikörper) fusion oncoprotein (PML (zeige PML Antikörper)-RARalpha (zeige RARA Antikörper)) is a key event during acute promyelocytic leukemia (zeige PML Antikörper) (APL (zeige FASL Antikörper)) pathogenesis.

  6. Hhex binds to the Cdkn2a (zeige CDKN2A Antikörper) locus and directly interacts with the Polycomb (zeige CBX2 Antikörper)-repressive complex 2 (PRC2) to enable H3K27me3-mediated epigenetic repression

  7. Data suggest that Hhex is a novel regulator of c-Myc (zeige MYC Antikörper) function that limits c-Myc (zeige MYC Antikörper) activity in transformed cells.

  8. PRH controls the migration of multiple epithelial cell lineages in part at least through the direct transcriptional regulation of Endoglin (zeige ENG Antikörper)

  9. HHEX promotes hepatic specification by repressing EOMES (zeige EOMES Antikörper) expression.

  10. Data indicate the potential importance of CDKAL1 (zeige CDKAL1 Antikörper) protein and homeobox protein HHEX in glucose homeostasis in this Alaska Native population with a low prevalence of type 2 diabetes (T2D).

Mouse (Murine) Hematopoietically Expressed Homeobox (HHEX) Interaktionspartner

  1. The Hhex evolutionarily conserved non-coding region appears to be a core node for the convergence of the transcription factor network that governs the emergence of Hematopoietic stem cells.

  2. Hhex(-/-) mESCs fail to differentiate from definitive endoderm to hepatic endoderm.

  3. results implicate Hhex in the maintenance of LT-HSCs and in lineage allocation from multipotent progenitors especially in stress hematopoiesis.

  4. Data suggest that Hhex is a novel regulator of c-Myc (zeige MYC Antikörper) function that limits c-Myc (zeige MYC Antikörper) activity in transformed cells.

  5. Hhex regulates Kit to promote radioresistance of self-renewing thymocytes in Lmo2 (zeige LMO2 Antikörper)-transgenic mice.

  6. Hhex is a key regulator of early lymphoid development, functioning, at least in part, via regulation of the cell cycle.

  7. Hhex and Cer1 (zeige CER1 Antikörper) are indispensable components of the Sox17 (zeige SOX17 Antikörper) pathway for cardiopoiesis.

  8. Hhex as the first transcriptional regulator specifically required for islet delta cells and suggest compromised paracrine control as a contributor to T2DM

  9. Data suggest that GPC3 (zeige GPC3 Antikörper) down-regulates hepatocyte proliferation by binding to hedgehog (zeige SHH Antikörper) (HH) and down-regulating the HH signaling pathway and binding with CD81 (zeige CD81 Antikörper), thus making it unavailable to bind to Hhex and causing its nuclear translocation.

  10. Hex expression and subcellular localization are associated with chondrocyte maturation

Zebrafish Hematopoietically Expressed Homeobox (HHEX) Interaktionspartner

  1. hhex, nk2.1a, and pax2.1 regulate thyroid growth and differentiation downstream of Nodal-dependent transcription factors.

  2. Data suggest that zebrafish hhex appears to be activated by Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) in the dorsal yolk syncytial layer, where bozozok acts in a permissive way to limit repression of hhex by Vega1 and Vega2.

Hematopoietically Expressed Homeobox (HHEX) Antigen-Profil

Protein Überblick

This gene encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation.

Genbezeichner und Symbole assoziert mit HHEX

  • Homeobox protein PRH (Bm1_31285) Antikörper
  • hematopoietically expressed homeobox (hhex) Antikörper
  • hematopoietically expressed homeobox (HHEX) Antikörper
  • hematopoietically expressed homeobox (Hex1) Antikörper
  • hematopoietically expressed homeobox L homeolog (hhex.L) Antikörper
  • hematopoietically expressed homeobox (Hhex) Antikörper
  • HEX Antikörper
  • Hex1 Antikörper
  • HHEX Antikörper
  • hhex-A Antikörper
  • Hhex-rs2 Antikörper
  • HMPH Antikörper
  • HOX11L-PEN Antikörper
  • Prh Antikörper
  • Prhx Antikörper
  • PROBOX Antikörper
  • tHex Antikörper
  • XHex Antikörper

Bezeichner auf Proteinebene für HHEX

Homeobox protein PRH , hematopoietically-expressed homeobox protein hhex , homeobox protein hex , homeodomain transcription factor , hematopoietically expressed homeobox , hematopoietically-expressed homeobox protein HHEX , homeobox protein HEX , homeobox protein PRH , homeobox, hematopoietically expressed , proline-rich homeodomain-containing transcription factor , hematopoietically expressed homeobox protein , hematopoietically expressed homeobox, related sequence 2 , hematopoietically-expressed homeobox protein Hhex , mHex

GENE ID SPEZIES
6101149 Brugia malayi
100305190 Oncorhynchus mykiss
395060 Xenopus (Silurana) tropicalis
450612 Pan troglodytes
7235725 Branchiostoma floridae
100303530 Saccoglossus kowalevskii
373590 Xenopus laevis
3087 Homo sapiens
608175 Canis lupus familiaris
397232 Sus scrofa
539542 Bos taurus
15242 Mus musculus
79237 Rattus norvegicus
396182 Gallus gallus
30098 Danio rerio
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