anti-Heat Shock 22kDa Protein 8 (HSPB8) Antikörper

The protein encoded by HSPB8 belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. Zusätzlich bieten wir Ihnen Heat Shock 22kDa Protein 8 Proteine (23) und Heat Shock 22kDa Protein 8 Kits (15) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
HSPB8 26353 Q9UJY1
HSPB8 80888 Q9JK92
HSPB8 113906 Q9EPX0
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Top anti-Heat Shock 22kDa Protein 8 Antikörper auf antikoerper-online.de

Showing 10 out of 169 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-HSPB8 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>Human Placenta 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-HSPB8 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>ACHN cell lysate WB Suggested Anti-HSPB8 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500 <br /> Positive Control: ACHN cell lysate <br /> HSPB8 is supported by BioGPS gene expression data to be expressed in ACHN 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert ELISA, WB ABIN184852 staining (1µg/ml) of human muscle lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Maus Unkonjugiert ICC, IF, IHC, ELISA, WB HSP22 (3C12 H11), Mouse backskin. Rat tissue Mix WB 1 in 1000 Hsp22 monomer and dimer. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$383.90
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Hund Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details
Human Ziege Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$411.13
Details
Human Maus HRP ICC, IF, IHC, ELISA, WB Immunohistochemistry analysis using Mouse Anti-Hsp22 Monoclonal Antibody, Clone 3C12-H11 . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-Hsp22 Monoclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Localization: Granular layer of the epidermis. Some dermal staining. Western Blot analysis of Rat Cell lysates showing detection of Hsp22 protein using Mouse Anti-Hsp22 Monoclonal Antibody, Clone 3C12-H11 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Hsp22 Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$422.40
Details
Human Maus FITC ICC, IF, IHC, ELISA, WB Immunohistochemistry analysis using Mouse Anti-Hsp22 Monoclonal Antibody, Clone 3C12-H11 . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-Hsp22 Monoclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Localization: Granular layer of the epidermis. Some dermal staining. Western Blot analysis of Rat Cell lysates showing detection of Hsp22 protein using Mouse Anti-Hsp22 Monoclonal Antibody, Clone 3C12-H11 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Hsp22 Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$426.80
Details
Human Maus Alkaline Phosphatase (AP) ICC, IF, IHC, ELISA, WB Immunohistochemistry analysis using Mouse Anti-Hsp22 Monoclonal Antibody, Clone 3C12-H11 . Tissue: backskin. Species: Mouse. Fixation: Bouin's Fixative and paraffin-embedded. Primary Antibody: Mouse Anti-Hsp22 Monoclonal Antibody  at 1:100 for 1 hour at RT. Secondary Antibody: FITC Goat Anti-Mouse (green) at 1:50 for 1 hour at RT. Localization: Granular layer of the epidermis. Some dermal staining. Western Blot analysis of Rat Cell lysates showing detection of Hsp22 protein using Mouse Anti-Hsp22 Monoclonal Antibody, Clone 3C12-H11 . Load: 15 µg. Block: 1.5% BSA for 30 minutes at RT. Primary Antibody: Mouse Anti-Hsp22 Monoclonal Antibody  at 1:1000 for 2 hours at RT. Secondary Antibody: Sheep Anti-Mouse IgG: HRP for 1 hour at RT. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$429.00
Details

HSPB8 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-Heat Shock 22kDa Protein 8 Antikörper

  1. Human Polyclonal HSPB8 Primary Antibody für ELISA, WB - ABIN249692 : Benndorf, Sun, Gilmont, Biederman, Molloy, Goodmurphy, Cheng, Andrews, Welsh: HSP22, a new member of the small heat shock protein superfamily, interacts with mimic of phosphorylated HSP27 ((3D)HSP27). in The Journal of biological chemistry 2001 (PubMed)

  2. Human Polyclonal HSPB8 Primary Antibody für ICC, IF - ABIN4320602 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)

Weitere Antikörper gegen Heat Shock 22kDa Protein 8 Interaktionspartner

Human Heat Shock 22kDa Protein 8 (HSPB8) Interaktionspartner

  1. suggest that HSPB8 may act as an intracellular factor against hepatitis C virus replication and that DNAJC5B has the same function, with more relevant results for genotype 3

  2. It has been demonstrated that HSPB8-BAG3 (zeige BAG3 Antikörper)-HSP70 (zeige HSP70 Antikörper) ensures the functionality of stress granules and restores proteostasis by targeting defective ribosomal products for degradation.

  3. We report that overexpression of HSPB8 in immortalized motor neurones decreased the accumulation of TDP-25 and TDP-35 and that protection against mislocalized/truncated TDP-43 (zeige TARDBP Antikörper) was observed for HSPB8 in Drosophila melanogaster Overexpression of HSP67Bc, the functional ortholog of human HSPB8, suppressed the eye degeneration caused by the cytoplasmic accumulation of a TDP-43 (zeige TARDBP Antikörper) variant

  4. HSPB8 counteracts accumulation of aberrantly localized misfolded forms of TDP-43 (zeige TARDBP Antikörper) and its 25 KDa fragment involved in most sporadic cases of Amyotrophic Lateral Sclerosis and of Fronto Lateral Temporal Dementia.

  5. expands the understanding of disease mechanisms, tissue involvement, and phenotypic outcome of HSPB8 mutations

  6. our findings suggest the existence of a so-far unrecognized quality control mechanism involving BAG3 (zeige BAG3 Antikörper), HSPB8 and p62/SQSTM1 (zeige SQSTM1 Antikörper) for accurate remodelling of actin-based mitotic structures that guide spindle orientation.

  7. This study demonstreated that expression of HSPB8 was restricted to GFAP (zeige GFAP Antikörper)+ astrocytes in patient with multiple sclerosis.

  8. Pangenomic profiling of velcade-sensitive and resistant cells showed that the small heat shock protein HSPB8 was overexpressed in multiple myeloma resistant cells.

  9. HSP22 acts as a positive regulator in TGF-alpha (zeige TGFA Antikörper)-induced migration of ovarian cancer cells, subsequently directing ovarian cancer toward progression.

  10. HSP22 plays an important role on gastric tumor aggressiveness and prognosis and may act as a promising target for prognostic prediction.

Cow (Bovine) Heat Shock 22kDa Protein 8 (HSPB8) Interaktionspartner

  1. GA genotype of SNP g.507G>A of HSPB8 gene has a probable role in heat tolerance in Sahiwal cattle.

Mouse (Murine) Heat Shock 22kDa Protein 8 (HSPB8) Interaktionspartner

  1. HSP22 functions as a negative regulator in the TGF-beta (zeige TGFB1 Antikörper)-stimulated migration of osteoblasts.

  2. Results revealed that the apoptosis-suppressing effect of heat shock protein B8 was mediated by the PI3K/Akt (zeige AKT1 Antikörper) pathway in an in vitro model of ischemia.

  3. Increased Hsp20 (zeige HSPB6 Antikörper) expression protects against OGDR-induced Golgi fragmentation and apoptosis, likely through interaction with Bax (zeige BAX Antikörper) and subsequent amelioration of the OGDR-induced elevation in p115 (zeige ARHGAP4 Antikörper) cleavage via the Fas (zeige FAS Antikörper)/FasL (zeige FASL Antikörper) signaling pathway.

  4. Translocation of both Hsp22 and iNOS to the mitochondria is necessary for Hsp22-mediated stimulation of oxidative phosphorylation

  5. analysis of the phenotype of cardiomyopathy in cardiac-specific heat shock protein B8 K141N transgenic mouse

  6. The results of this study strongly suggested that Hspb8 and its alpha-crystallin domain might act as pleiotropic prosurvival factor in the adult hippocampus.

  7. Hspb8 mRNA is constitutively expressed in specific brain structures across ontogeny; eventually these structures could be affected by the malfunction or deregulation of the Hspb8 molecule.

  8. Hsp22 represents a previously undescribed activator of both nuclear and mitochondrial functions of STAT3 (zeige STAT3 Antikörper), and its deletion in the context of pressure overload in vivo accelerates the transition into heart failure and increases mortality.

  9. HspB8 increases misfolded SOD1 (zeige SOD1 Antikörper) clearance via autophagy.

  10. Findings show that despite the ubiquitous presence of HSPB8, only motor neurons appear to be affected by the K141N and K141E mutations.

Heat Shock 22kDa Protein 8 (HSPB8) Antigen-Profil

Protein Überblick

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.

Genbezeichner und Symbole assoziert mit HSPB8

  • heat shock protein family B (small) member 8 L homeolog (hspb8.L) Antikörper
  • heat shock protein family B (small) member 8 (HSPB8) Antikörper
  • heat shock protein b8 (hspb8) Antikörper
  • heat shock protein 8 (Hspb8) Antikörper
  • heat shock protein family B (small) member 8 (Hspb8) Antikörper
  • AU018630 Antikörper
  • AW413033 Antikörper
  • CMT2L Antikörper
  • Cryac Antikörper
  • D5Ucla4 Antikörper
  • DHMN2 Antikörper
  • E2IG1 Antikörper
  • fc09c11 Antikörper
  • H11 Antikörper
  • H11K Antikörper
  • HMN2 Antikörper
  • HMN2A Antikörper
  • HSP20-like Antikörper
  • Hsp22 Antikörper
  • MGC64408 Antikörper
  • wu:fc04b04 Antikörper
  • wu:fc09c11 Antikörper
  • zgc:64202 Antikörper

Bezeichner auf Proteinebene für HSPB8

heat shock 22kDa protein 8 , heat shock 27kDa protein 8 , heat shock protein beta-8 , E2-induced gene 1 protein , alpha-crystallin C chain , protein kinase H11 , small stress protein-like protein HSP22 , H11 kinase , crystallin, alpha C , heat shock protein 20-like protein , heat shock protein 8

GENE ID SPEZIES
379472 Xenopus laevis
416988 Gallus gallus
452295 Pan troglodytes
100174469 Pongo abelii
100349029 Oryctolagus cuniculus
791580 Danio rerio
26353 Homo sapiens
403553 Canis lupus familiaris
539524 Bos taurus
574341 Macaca mulatta
80888 Mus musculus
113906 Rattus norvegicus
Ausgewählte Anbieter für anti-Heat Shock 22kDa Protein 8 (HSPB8) Antikörper
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