HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1) ELISA Kits

E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Zusätzlich bieten wir Ihnen HACE1 Antikörper (27) und HACE1 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
HACE1 57531 Q8IYU2
HACE1 209462 Q3U0D9
HACE1 361866 D3ZBM7
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Top HACE1 ELISA Kits auf antikoerper-online.de

Showing 6 out of 10 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 6.25 pg/mL 25-1600 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
772,39 €
Details
Human 0.054 ng/mL 0.156-10 ng/mL   96 Tests Anmelden zum Anzeigen 6 bis 8 Tage
653,71 €
Details
Maus 0.78-50 ng/mL   96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
788,70 €
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Ratte
  96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
788,70 €
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Rind (Kuh)
  96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
945,85 €
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Huhn
  96 Tests Anmelden zum Anzeigen 13 bis 17 Tage
1.013,20 €
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Weitere ELISA Kits für HACE1 Interaktionspartner

Human HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1) Interaktionspartner

  1. HACE1 can act as a haploinsufficient tumor suppressor gene in most B-cell lymphomas and can be downregulated by deacetylation of its promoter region chromatin

  2. Hepatocellular carcinoma patients with low HACE1 expression levels exhibited poorer overall survival and HACE1 was found to be an independent prognostic factor for survival.

  3. HACE1 as a specific E3 ligase that polyubiquitinates YB-1 through non-canonical K27 linked ubiquitin chains.

  4. Biallelic loss-of-function mutations in HACE1 are associated with an autosomal recessive neurodevelopmental syndrome.

  5. supports a critical role for HACE1 in breast cancer progression and identifies patients that may benefit from Rac (zeige AKT1 ELISA Kits)-targeted therapies

  6. contrary to previous report, overexpression of HACE1 by transduction of recombinant protein did not affect proliferation or survival of NKTCL cell lines. We therefore conclude that HACE1 is not directly involved in NKTCL pathophysiology

  7. HACE1-OPTN (zeige OPTN ELISA Kits) axis synergistically suppresses growth and tumorigenicity of lung cancer cells.

  8. Ubiquitylation and activation of RAB11a (zeige RAB11A ELISA Kits) is promoted by a beta2 adrenergic receptor (zeige ADRB2 ELISA Kits)-HACE1 complex.

  9. HACE1 reduces oxidative stress and mutant Huntingtin (zeige HTT ELISA Kits) toxicity by promoting the NRF2 (zeige GABPA ELISA Kits) response.

  10. All stages of HCCs (zeige HCCS ELISA Kits) presented HACE1 methylation, indicating that the HACE1 gene has been methylated from the early stages of HCCs (zeige HCCS ELISA Kits).

Mouse (Murine) HECT Domain and Ankyrin Repeat Containing, E3 Ubiquitin Protein Ligase 1 (HACE1) Interaktionspartner

  1. Increased reactive oxygen species (ROS (zeige ROS1 ELISA Kits)) production due to Hace1 loss leads to glutamine (zeige GFPT1 ELISA Kits) addiction as a mechanism to cope with increased ROS (zeige ROS1 ELISA Kits)-induced oxidative stress.

  2. Data indicate that HECT E3 ubiquitin ligase HACE1 deficiency accelerates pressure overload-induced heart failure.

  3. HACE1-OPTN (zeige OPTN ELISA Kits) axis synergistically suppresses growth and tumorigenicity of lung cancer cells.

  4. Hace1 controls ROS (zeige ROS1 ELISA Kits) generation of vertebrate Rac1-dependent NADPH oxidase (zeige NOX1 ELISA Kits) complexes.

HACE1 Antigen-Profil

Beschreibung des Gens

E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB (By similarity).

Genbezeichner und Symbole assoziert mit HACE1

  • HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 (HACE1) Antikörper
  • HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 (HACE1) Antikörper
  • HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1 (hace1) Antikörper
  • HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 (LOC100342048) Antikörper
  • HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 (hace1) Antikörper
  • HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 (Hace1) Antikörper
  • 1700042J16Rik Antikörper
  • A730034A22Rik Antikörper
  • BC025474 Antikörper
  • HACE1 Antikörper

Bezeichner auf Proteinebene für HACE1

HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 , E3 ubiquitin-protein ligase HACE1 , HECT domain and ankyrin repeat-containing E3 ubiquitin-protein ligase 1 , E3 ubiquitin-protein ligase HACE1-like , e3 ubiquitin-protein ligase HACE1-like

GENE ID SPEZIES
100071887 Equus caballus
462900 Pan troglodytes
734146 Xenopus (Silurana) tropicalis
100342048 Oryctolagus cuniculus
100399774 Callithrix jacchus
100438368 Pongo abelii
100475389 Ailuropoda melanoleuca
100548893 Meleagris gallopavo
100562508 Anolis carolinensis
100581995 Nomascus leucogenys
446912 Xenopus laevis
421788 Gallus gallus
57531 Homo sapiens
475010 Canis lupus familiaris
100156102 Sus scrofa
527565 Bos taurus
209462 Mus musculus
361866 Rattus norvegicus
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