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Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) ELISA Kits

Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. Zusätzlich bieten wir Ihnen GNAI1 Antikörper (64) und GNAI1 Proteine (12) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Maus GNAI1 GNAI1 14677 B2RSH2
Anti-Human GNAI1 GNAI1 2770 P63096
Anti-Ratte GNAI1 GNAI1 25686 P10824
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Weitere ELISA Kits für GNAI1 Interaktionspartner

Mouse (Murine) Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) Interaktionspartner

  1. stimulation of GPR17 (zeige GPR17 ELISA Kits) by the small molecule agonist MDL29,951 (2-carboxy-4,6-dichloro-1H-indole-3-propionic acid) decreases myelin basic protein (zeige MBP ELISA Kits) expression levels mainly by triggering the Galphai/o signaling pathway.

  2. Gnai1 missense mutation is responsible of hyperpigmentation in mouse model.

  3. acidosis in inflamed tissues may be a decisive factor to regulate switching of PKA and PKCepsilon dependence via proton-sensing G-protein-coupled receptors.

  4. Data show that guanine nucleotide-binding protein G(i) subunit alpha-1 and alpha-3 (Galphai1/3) can interact with CD14 antigen/Grb2-associated binding protein Gab1, which modulates macrophage polarization in vitro and in vivo.

  5. By using mice deficient in individual Galphai/o G-protein subunits, authors demonstrate that Galphai1 and Galphai3 are the critical in vivo targets of ADP-ribosylation underlying vasoactive amine sensitization elicited by pertussis toxin exposure.

  6. leucine can directly facilitate insulin (zeige INS ELISA Kits) signaling through a Galphai protein-dependent intracellular signaling pathway

  7. Inactive Galpha(i1)-GDP enhances the affinity of RGS14 for H-Ras-GTP in live cells, resulting in a ternary signaling complex that is further regulated by G protein-coupled receptors.

  8. Mice with mutations of Gnai1 or Gnai2 (zeige GNAI2 ELISA Kits) have neither fusions of ribs nor lumbar vertebrae, but loss of both Gnai3 (zeige GNAI3 ELISA Kits) and one of the other two genes increases the number and severity of rib fusions without affecting the lumbar fusions.

  9. Results suggest a model in which the Gbetagamma dimer that is released as a result of the dissociation from Galpha(o (zeige GNAO1 ELISA Kits)) upon activation of mGluR6 (zeige GRM6 ELISA Kits) closes the TRPM1 (zeige TRPM1 ELISA Kits) channel, perhaps via a direct interaction.

  10. RGS14 (zeige RGS16 ELISA Kits) can form complexes with GPCRs in cells that are dependent on Galpha (zeige SUCLG1 ELISA Kits)(i/o) and these RGS14 (zeige RGS16 ELISA Kits).Galpha (zeige SUCLG1 ELISA Kits)(i1).GPCR (zeige GPBAR1 ELISA Kits) complexes may be substrates for other signaling partners such as Ric-8A (zeige RIC8A ELISA Kits)

Human Guanine Nucleotide Binding Protein (G Protein), alpha Inhibiting Activity Polypeptide 1 (GNAI1) Interaktionspartner

  1. Data indicate that hydroxyurea (HU) induces SAR1 (zeige IQGAP1 ELISA Kits) protein expression, which in turn activates gamma-globin (zeige HBG1 ELISA Kits) expression, predominantly through the Gialpha/JNK (zeige MAPK8 ELISA Kits)/Jun (zeige JUN ELISA Kits) pathway.

  2. Gi alpha subunit (zeige POLG ELISA Kits) was found to be a key modulator of GABAB-receptors signaling in analgesia.

  3. AC5, by binding active Galphai1, interferes with G-protein deactivation and reassembly and thereby might sensitize its own regulation.

  4. Data indicate that focal adhesion kinase (FAK) activation and cell migration require Src, Gi/Go, COX-2 and LOXs activities.

  5. resistin (zeige RETN ELISA Kits) contributes to the pro-inflammatory state of SMC (zeige DYM ELISA Kits) by the up-regulation of CX3CL1 (zeige CX3CL1 ELISA Kits) and CX3CR1 (zeige CX3CR1 ELISA Kits) expression via a mechanism involving NF-kB, AP-1 (zeige FOSB ELISA Kits), and STAT1 (zeige STAT1 ELISA Kits)/3 transcription factors, (2) resistin (zeige RETN ELISA Kits) employs TLR4 (zeige TLR4 ELISA Kits) and Gi-protein signaling.

  6. leucine can directly facilitate insulin (zeige INS ELISA Kits) signaling through a Galphai protein-dependent intracellular signaling pathway

  7. Data suggest that chemokine (zeige CCL1 ELISA Kits) binding to CCX-CKR (zeige CCRL1 ELISA Kits) (a) recruits Gi proteins and beta-arrestin (beta-arr (zeige SAG ELISA Kits)) with high affinity.

  8. This study support a role for RGS (zeige PITX2 ELISA Kits) proteins as negative regulators of opioid supraspinal antinociception and also reveal a potential novel function of RGS (zeige PITX2 ELISA Kits) proteins as positive regulators of opioid spinal antinociceptive pathways.

  9. Galpha(o (zeige GNAO1 ELISA Kits)) protein contributes to maximally efficient mu-opioid receptor (zeige OPRM1 ELISA Kits) signaling and antinociception in Galpha(o (zeige GNAO1 ELISA Kits)) null transgenic mice.

  10. CXCL12 (zeige CXCL12 ELISA Kits) signaling via CXCR7 (zeige CXCR7 ELISA Kits) is Gialpha independent.

GNAI1 Antigen-Profil

Beschreibung des Gens

Guanine nucleotide binding proteins are heterotrimeric signal-transducing molecules consisting of alpha, beta, and gamma subunits. The alpha subunit binds guanine nucleotide, can hydrolyze GTP, and can interact with other proteins. The protein encoded by this gene represents the alpha subunit of an inhibitory complex. The encoded protein is part of a complex that responds to beta-adrenergic signals by inhibiting adenylate cyclase. Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit GNAI1

  • guanine nucleotide binding protein (G protein), alpha inhibiting 1 (Gnai1) Antikörper
  • guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 (gnai1-b) Antikörper
  • guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 (GNAI1) Antikörper
  • guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 (Gnai1) Antikörper
  • guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 (gnai1) Antikörper
  • AU046200 Antikörper
  • BPGTPB Antikörper
  • Gi Antikörper
  • Gialpha1 Antikörper
  • Gnai-1 Antikörper
  • gnai1 Antikörper
  • zgc:63957 Antikörper

Bezeichner auf Proteinebene für GNAI1

adenylate cyclase-inhibiting G alpha protein , guanine nucleotide binding protein, alpha inhibiting 1 , guanine nucleotide-binding protein G(i) subunit alpha-1 , Gi1 protein alpha-subunit , alpha-subunit of G-protein, type G-alpha-i-1 , guanine nucleotide-binding protein G(i), alpha-1 subunit , Gi1 protein alpha subunit , Gi-alpha-1 protein , guanine nucleotide binding protein (G protein), alpha inhibiting 1 , Galpha i1a

GENE ID SPEZIES
14677 Mus musculus
100135528 Cavia porcellus
399463 Xenopus laevis
396368 Gallus gallus
2770 Homo sapiens
397505 Sus scrofa
281790 Bos taurus
25686 Rattus norvegicus
393946 Danio rerio
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