Guanidinoacetate N-Methyltransferase Proteine (GAMT)

The protein encoded by GAMT is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Zusätzlich bieten wir Ihnen GAMT Antikörper (49) und GAMT Kits (5) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
GAMT 14431 O35969
GAMT 2593 Q14353
GAMT 25257  
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top GAMT Proteine auf antikoerper-online.de

Showing 10 out of 21 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,331.68
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$5,442.50
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$286.00
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Anmelden zum Anzeigen 4 Days
$369.60
Details
Hefe Ratte His tag Guanidinoacetate N-Methyltransferase (GAMT) (AA 1-236) protein (His tag) expressed in E. coli 1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,597.83
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$785.40
Details
HOST_Escherichia coli (E. coli) Human His tag   10 μg Anmelden zum Anzeigen 15 bis 16 Tage
$212.50
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$405.71
Details
Hefe Xenopus tropicalis His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,585.00
Details
Hefe Zebrafisch His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,592.33
Details

GAMT Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine) ,
,
Human , ,
, , ,
Rat (Rattus) ,
,

Weitere Proteine zu Guanidinoacetate N-Methyltransferase (GAMT) Interaktionspartnern

Mouse (Murine) Guanidinoacetate N-Methyltransferase (GAMT) Interaktionspartner

  1. Inactivation of the creatine kinase system by GAMT deficiency does not alter mitochondrial organization and intracellular compartmentation in relaxed cardiomyocytes.

  2. GAMT was expressed highly in oligodendrocytes and olfactory ensheathing glia and moderately in astrocytes, whereas GAMT was very low in neurons and microglia.

  3. despite the absence of Cr, GAMT-/- mice can cope with mild ischaemic stress by using phosphorylated guanidinoacetate for high energy phosphoryl transfer

  4. GAMT(Cr)-/- mice showed differences in maximal rates of force rise and relaxation times during the isometric protocol as well as in force during the dynamic protocol.

  5. Our results can provide the basis for additional experiments to optimize Cr supplementation in GAMT deficiency, as increases in brain Cr are slow in patients after Cr supplementation.

  6. GAMT and AGAT (zeige GATM Proteine) mRNA are up-regulated 5.4- and 1.9-fold respectively in adult mdx (zeige DMD Proteine) muscle compared to C57

  7. In the fetal brain, mRNA expression of GAMT was relatively low until 34 days gestation (term is 38-39 days). In the fetal kidney and liver, GAMT mRNA and protein expression were also relatively low until 34-37 days gestation.

Human Guanidinoacetate N-Methyltransferase (GAMT) Interaktionspartner

  1. Data suggest that creatine is provided equally by diet and by endogenous synthesis from arginine and glycine with successive involvement of arginine glycine amidinotransferase [AGAT (zeige GATM Proteine)] and guanidinoacetate methyl transferase [GAMT]. [REVIEW]

  2. As early diagnosis results in normal neurodevelopmental outcome, GAMT deficiency should be included in newborn screening programs to diagnose individuals at the asymptomatic stage of the disease

  3. The estimated incidence of GAMT deficiency is 1:250,000 newborns based on our pilot study.

  4. Study reports six novel pathogenic mutations in GAMT gene in patients with Guanidinoacetate methyltransferase deficiency.

  5. Two novel heterozygous variants with sequence deletion and sequence insertion in the GAMT gene have been identified in newborns with guanidinoacetate methyltransferase deficiency.

  6. impact of creatine deficiency syndrome mutations, CRTR (zeige SLC6A8 Proteine) and GAMT on metabolic stress was analyzed in patient fibroblast cultures

  7. GAMT genes may not be directly involved in human male infertility

  8. Mutations in the GAMT gene are responsible for GAMT deficiency, since overexpression of the GAMT open reading frame restores GAMT activity in GAMT-deficient fibroblasts.

  9. compound heterozygous mutations in the GAMT gene may be causitive in guanidinoacetate methyltransferase deficiency masquerading as a mitochondrial encephalopathy [case report]

  10. the carrier rate of the c.59G>C; p.Trp20Ser mutation in GAMT is relatively high in these islands, as well as in other parts of Portugal.

Zebrafish Guanidinoacetate N-Methyltransferase (GAMT) Interaktionspartner

  1. The spatiotemporal expression pattern of gamt during zebrafish embryogenesis was revealed.

GAMT Protein Überblick

Protein Überblick

The protein encoded by this gene is a methyltransferase that converts guanidoacetate to creatine, using S-adenosylmethionine as the methyl donor. Defects in this gene have been implicated in neurologic syndromes and muscular hypotonia, probably due to creatine deficiency and accumulation of guanidinoacetate in the brain of affected individuals. Two transcript variants encoding different isoforms have been described for this gene. Pseudogenes of this gene are found on chromosomes 2 and 13.

Genbezeichner und Symbole assoziert mit GAMT

  • guanidinoacetate N-methyltransferase (gamt)
  • guanidinoacetate N-methyltransferase (GAMT)
  • Guanidinoacetate N-methyltransferase (gamt)
  • guanidinoacetate methyltransferase (Gamt)
  • guanidinoacetate N-methyltransferase (Gamt)
  • AA571402 Protein
  • CCDS2 Protein
  • GAMT Protein
  • GMT Protein
  • MGC75698 Protein
  • PIG2 Protein
  • Spintz1 Protein
  • TP53I2 Protein
  • zgc:123136 Protein

Bezeichner auf Proteinebene für GAMT

guanidinoacetate N-methyltransferase , Guanidinoacetate N-methyltransferase , guanidinoacetate methyltransferase

GENE ID SPEZIES
394491 Xenopus (Silurana) tropicalis
485085 Canis lupus familiaris
749982 Pan troglodytes
770737 Gallus gallus
100196494 Salmo salar
100528342 Ictalurus punctatus
14431 Mus musculus
2593 Homo sapiens
515270 Bos taurus
25257 Rattus norvegicus
796865 Danio rerio
Ausgewählte Anbieter für GAMT Proteine (GAMT)
Haben Sie etwas anderes gesucht?