anti-Growth Differentiation Factor 9 (GDF9) Antikörper

Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. Zusätzlich bieten wir Ihnen GDF9 Kits (41) und GDF9 Proteine (16) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GDF9 2661 O60383
GDF9 14566 Q07105
GDF9 59304  
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Top anti-GDF9 Antikörper auf antikoerper-online.de

Showing 10 out of 134 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB GDF9 Antibody (N-term) (ABIN656116) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert IHC (p), WB The anti-GDF9 N-term Pab (ABIN388822) is used in Western blot to detect GDF9 in HL60 cell lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Anmelden zum Anzeigen 14 bis 16 Tage
335,24 €
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma reacted with GDF9 Antibody (N-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of GDF9 Antibody (N-term) in K562 cell line lysates (35ug/lane).This demonstrates the GDF9 antibody detected the GDF9 protein (arrow). 0.4 mL Anmelden zum Anzeigen 7 bis 9 Tage
407,00 €
Details
Human Maus Unkonjugiert CyTOF, FACS, ICC Detection of GDF-9 in OVCAR-3 Human Cell Line by Flow Cytometry. OVCAR-3 human ovarian carcinoma cell line was stained with Mouse Anti-Human GDF-9 Monoclonal Antibody. GDF-9 in OVCAR-3 Human Cell Line. GDF-9 was detected in immersion fixed OVCAR-3 human ovarian carcinoma cell line using Mouse Anti-Human GDF-9 Monoclonal Antibody. Specific staining was localized to secreted molecule. 100 μg Anmelden zum Anzeigen 3 bis 4 Tage
260,00 €
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
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Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 13 Days
154,33 €
Details
Human Maus Unkonjugiert Func, IHC (fro), IHC (p), WB 0.1 mg Anmelden zum Anzeigen 4 bis 5 Tage
271,76 €
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Lane 1: human colon carcinoma lysates Lane 2: mouse embryo lysates probed with Anti AVPR2 Polyclonal Antibody, Unconjugated (ABIN1386214) at 1:200 in 4 °C. Followed by conjugation to secondary antibody at 1:3000 90min in 37 °C. Predicted band 50kD. Observed band size: 50kD. 100 μL Anmelden zum Anzeigen 9 bis 12 Tage
304,36 €
Details
Human Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of GDF9 staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. AEC was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of GDF9 expression in HL60 (A) whole cell lysates. 200 μL Anmelden zum Anzeigen 11 bis 13 Tage
464,29 €
Details

GDF9 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-GDF9 Antikörper

  1. Human Monoclonal GDF9 Primary Antibody für Func, IHC (fro) - ABIN2473774 : McHugh, Marshall, Ffytche, Hamilton, Raven: Diode laser trabeculoplasty (DLT) for primary open-angle glaucoma and ocular hypertension. in The British journal of ophthalmology 1991 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal GDF9 Primary Antibody für IHC (p), WB - ABIN388822 : Hendarto, Prabowo, Moeloek, Soetjipto: Growth differentiation factor 9 concentration in the follicular fluid of infertile women with endometriosis. in Fertility and sterility 2010 (PubMed)
    Show all 2 Pubmed References

Weitere Antikörper gegen GDF9 Interaktionspartner

Zebrafish Growth Differentiation Factor 9 (GDF9) Interaktionspartner

  1. GDF9 expression was highest in primary growth follicles and gradually decreased during follicular development. Lowest level was found in fully grown follicles. It was maintained through fertilization and early embryonic development until gastrulation.

Human Growth Differentiation Factor 9 (GDF9) Interaktionspartner

  1. Human GDF9 and BMP15 (zeige BMP15 Antikörper) act synergistically to stimulate granulosa cell proliferation, a response that also involves species-specific non-SMAD (zeige SMAD1 Antikörper) signalling pathways.

  2. these results indicated that the GDF9 C447T SNP is a possible candidate genetic risk factor for female infertility in the Polish population.

  3. GDF-9 promotes the proliferation and migration of keloid fibroblasts via a mechanism involving the Smad2 (zeige SMAD2 Antikörper)/3 pathway.

  4. GDF9 c.169G>T (D57Y), c.546G>A (rs1049127), and BMP15 (zeige BMP15 Antikörper) rs79377927 (788_789insTCT) were associated with premature ovarian failure in the Chinese Hui population.

  5. results support a model of activation for human GDF9 dependent on cumulin formation through heterodimerization with BMP15 (zeige BMP15 Antikörper). Oocyte-secreted cumulin is likely to be a central regulator of fertility in mono-ovular mammals.

  6. GDF-9 and GDF-15 (zeige GDF15 Antikörper) levels may influence bone parameters in polycystic ovary syndrome

  7. GDF9 and BMP15 (zeige BMP15 Antikörper) expression is reduced in primordial, primary, and secondary follicles in ovarian tissues of PCOS patients.

  8. The arginine residue in the pre-helix loop of GDF9 homodimer may prevent the inhibition from its pro-domain or directly alter receptor binding, but this residue in GDF9 does not significantly affect the heterodimer activity.

  9. Eleven unique copy number changes are identified in a total of 11 patients, including a tandem duplication of 475 bp, containing part of the GDF9 gene promoter region.

  10. Data suggest up-regulation of mRNA for GDF9 and BMP15 (bone morphogenetic protein 15 (zeige BMP15 Antikörper)) in cumulus granulosa cells serves as biomarker for oocyte maturation, fertilization, embryo quality, and pregnancy in couples undergoing ICSI for male infertility.

Mouse (Murine) Growth Differentiation Factor 9 (GDF9) Interaktionspartner

  1. Data show that Rac1 induced nuclear import of STAT3 (zeige STAT3 Antikörper) by physical binding, and nuclear STAT3 (zeige STAT3 Antikörper) directly activated the transcription of essential oocyte-specific genes, including Jagged1 (zeige JAG1 Antikörper), GDF9 and BMP15 (zeige BMP15 Antikörper).

  2. In organogenesis of the ovary, production of Dhh (zeige DHH Antikörper)/Ihh (zeige IHH Antikörper) in granulosa cells requires growth differentiation factor 9 from the oocyte.

  3. results support a model of activation for human GDF9 dependent on cumulin formation through heterodimerization with BMP15 (zeige BMP15 Antikörper). Oocyte-secreted cumulin is likely to be a central regulator of fertility in mono-ovular mammals.

  4. The arginine residue in the pre-helix loop of GDF9 homodimer may prevent the inhibition from its pro-domain or directly alter receptor binding, but this residue in GDF9 does not significantly affect the heterodimer activity during heterodimer formation.

  5. modified oocyte glycoproteins alter GDF9:BMP15 (zeige BMP15 Antikörper) expression modifying follicle development resulting in the generation of more follicles

  6. A novel role for GDF9 in causing reproductive defects and suppressing tumor initiation in the Inha (zeige INHA Antikörper)(-/-) mouse model.

  7. Embryo vitrification has no effect on ovarian morphology or expression of GDF9.

  8. The results show that chronic unpredictable stress suppresses GDF9 expression.

  9. show that purified mature regions of GDF9 and BMP15 (zeige BMP15 Antikörper) synergistically interact in a specific manner which is not dependent on the presence of a pro-region.

  10. GDF9 may contribute to the variation observed in follicular development, ovulation rate, and fecundity between mammals

Pig (Porcine) Growth Differentiation Factor 9 (GDF9) Interaktionspartner

  1. These results show that GDF9 and BMP15 (zeige BMP15 Antikörper) participate in cumulus expansion and that they stimulate MPF (zeige MSLN Antikörper) and MAPK (zeige MAPK1 Antikörper) activities in porcine oocytes during in vitro maturation.

  2. Report temporal regulation of GDF9 mRNA expression in the oocyte, granulosa and theca cells of developing preovulatory follicles in the pig.

  3. injection of porcine GDF-9 gene resulted in an increase in the number of primary, secondary and tertiary ovarian follicles

  4. Porcine GDF9 gene was found to be highly expressed in immature oocytes and declined slowly during the oocyte maturation process

  5. GDF9 may be not associated with pig litter size in extensive populations as per the studies of allele distributions of the four polymorphisms and pilot association in four breeds.

Cow (Bovine) Growth Differentiation Factor 9 (GDF9) Interaktionspartner

  1. Immunization against GDF9 and BMP15 (zeige BMP15 Antikörper), alone or together, altered follicular development and ovulation rate in cattle.

  2. GDF9 expression in the oocytes of calf ovaries was significantly higher than in those of the adult ovaries

  3. GDF-9 mediates its effect through the pathway commonly activated by TGF beta (zeige TGFB1 Antikörper) and activin (zeige Actbeta Antikörper), but not that activated by many BMPs

  4. Maternal GDF9 transcripts persisted during oocyte in vitro maturation and fertilization and in preimplantation embryo until the five- to eight-cell or morula stage, but transcription was not reactivated at the time of embryonic genome activation.

  5. Oocyte- and granulosa cell-derived GDF9 may simultaneously promote theca cell proliferation and prevent premature differentiation of the theca interna during early follicle development.

Goat Growth Differentiation Factor 9 (GDF9) Interaktionspartner

  1. A non-synonymous mutation in GDF9 is highly associated with litter size in Chinese cashmere goats

  2. Studied six SNPs in goat BMPR1B (zeige BMPR1B Antikörper), BMP15 (zeige BMP15 Antikörper), and GDF9 for their association with litter size in seven breeds of Indian goats. Found no association between these SNPs and prolificacy in the breeds investigated.

  3. Expression of BMP15 (zeige BMP15 Antikörper) (p < 0.01) and GDF9 (p < 0.05) mRNAs was more abundant in the small than the large antral follicles of Black Bengal goat.

  4. GNRH1 (zeige GNRH1 Antikörper) and GDF9 genes could serve as genetic markers for litter size in goat breeding.

  5. Mutation A959C in GDF9 gene has been associated with prolificacy.

  6. Expression levels of follicular GDF9 and total ovarian BMPR1B (zeige BMPR1B Antikörper) were not different between the Lezhi black goat and the Tibetan goat.

  7. These results provide further evidence that the GDF9 gene may be significantly correlated with high prolificacy in goats.

GDF9 Antigen-Profil

Protein Überblick

Growth factors synthesized by ovarian somatic cells directly affect oocyte growth and function. Growth differentiation factor-9 (GDF9) is expressed in oocytes and is thought to be required for ovarian folliculogenesis. GDF9 is a member of the transforming growth factor-beta superfamily.

Genbezeichner und Symbole assoziert mit GDF9

  • growth differentiation factor 9 (GDF9) Antikörper
  • growth differentiation factor 9 (gdf9) Antikörper
  • growth differentiation factor 9 (Gdf9) Antikörper
  • Gdf-9 Antikörper
  • zgc:123030 Antikörper

Bezeichner auf Proteinebene für GDF9

growth and differentiation factor 9 , growth/differentiation factor 9 , GDF-9 , growth differentiation factor-9

GENE ID SPEZIES
100072822 Equus caballus
497643 Danio rerio
2661 Homo sapiens
14566 Mus musculus
59304 Rattus norvegicus
404533 Gallus gallus
100313495 Canis lupus familiaris
414285 Sus scrofa
282574 Bos taurus
100328727 Oryctolagus cuniculus
100735066 Cavia porcellus
100860859 Capra hircus
100217402 Ovis aries
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