anti-Growth Differentiation Factor 5 (GDF5) Antikörper

The protein encoded by GDF5 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. Zusätzlich bieten wir Ihnen GDF5 Kits (66) und GDF5 Proteine (37) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GDF5 8200 P43026
GDF5 14563 P43027
GDF5 252835  
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Top anti-GDF5 Antikörper auf antikoerper-online.de

Showing 10 out of 142 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Mouse Target Name: GDF5 Sample Tissue: Mouse Liver Antibody Dilution: 1ug/ml WB Suggested Anti-GDF5 Antibody Titration: 1.0 ug/ml Positive Control: Placenta 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB The anti-GDF5 N-term Pab (ABIN388820) is used in Western blot to detect GDF5 in A549 cell lysate. Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with GDF5 antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB Immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue reacted with BMP14 / GDF5 Antibody (C-term) followed by peroxidase conjugation of the secondary antibody and DAB staining. Western blot analysis of BMP14 / GDF5 Antibody (C-term) in MDA-MB435 cell line lysates (35ug/lane). This demonstrates the GDF5 antibody detected the GDF5 protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB GDF5 Antibody (C-term)  western blot analysis in MDA-MB435 cell line lysates (35ug/lane).This demonstrates the GDF5 antibody detected the GDF5 protein (arrow). GDF5 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GDF5 Antibody (C-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: GDF-5/BMP-14 Antibody [NBP2-16632] - A: NIH-3T3 B: JC. Western Blot: GDF-5/BMP-14 Antibody [NBP2-16632] - A: 293T B: A431 C: H1299. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$514.63
Details
Human Kaninchen Unkonjugiert ELISA, IHC (p), WB Immunohistochemistry (IHC) analysis of paraffin-embedded Rat Brain, antibody was diluted at 1:100. 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Human Kaninchen Unkonjugiert EIA, IHC (p) 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$500.50
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry-Paraffin: GDF-5/BMP-14 Antibody [NBP1-88575] - Staining of human stomach shows strong cytoplasmic positivity in glandular cells. Western Blot: GDF-5/BMP-14 Antibody [NBP1-88575] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells) Lane 2: NBT-II cell lysate (Rat Wistar bladder tumour cells) 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert IHC (p), ELISA Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details

GDF5 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

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Am meisten referenzierte anti-GDF5 Antikörper

  1. Human Polyclonal GDF5 Primary Antibody für IHC (p), WB - ABIN388820 : Liu, Lin, Sytwu, Chang: GDF-5 is suppressed by IL-1beta and enhances TGF-beta3-mediated chondrogenic differentiation in human rheumatoid fibroblast-like synoviocytes. in Experimental and molecular pathology 2010 (PubMed)
    Show all 4 Pubmed References

Weitere Antikörper gegen GDF5 Interaktionspartner

Xenopus laevis Growth Differentiation Factor 5 (GDF5) Interaktionspartner

  1. Changes in the expression of downstream regulators of skeletal differentiation, like barx1 (zeige BARX1 Antikörper) and gdf5, is one mechanism by which head skeletal element number and articulation are altered during evolution.

  2. Results suggest that CDMP1/GDF5 requires cleavage by two distinct proteolytic enzymes.

Human Growth Differentiation Factor 5 (GDF5) Interaktionspartner

  1. BMP-14 rs143383 polymorphism reduced the susceptibility to knee osteoarthritis (OA) and hand OA not only in total analysis but also in subgroup analysis; BMP-14 rs143383 polymorphism may be a protective factor against OA occurrence

  2. The structure of Grem2 (zeige GREM2 Antikörper)-GDF5 complex has revealed a number of key findings for DAN-family mediated BMP2 (zeige BMP2 Antikörper) inhibition.

  3. miR (zeige MLXIP Antikörper)-615-3p negatively regulates the osteogenic differentiation of hLF (zeige EPAS1 Antikörper) cells through post-transcriptionally suppressing osteogenic regulators GDF5 and FOXO1 (zeige FOXO1 Antikörper).

  4. p38 (zeige CRK Antikörper), c-jun (zeige JUN Antikörper), and NFkappaB (zeige NFKB1 Antikörper) pathways activated during intervertebral disc degeneration by IL-1beta (zeige IL1B Antikörper) but not GDF-5

  5. GDF5 elicited significant (p < 0.05) changes in the expression of anabolic, catabolic and hypertrophic genes with several consistent effects in healthy donors and in OA patients

  6. GDF5 was up regulated in patients after chronic rhinosinusitis developing osteitis.

  7. he large array of modular enhancers for Gdf5 provide a new foundation for studying the spatial specificity of joint patterning in vertebrates, as well as new candidates for regulatory regions that may also influence osteoarthritis risk in human population

  8. The purpose of this study is to investigate the immunohistochemical expression of cytokeratin 18 (CK18 (zeige KRT18 Antikörper)) and the reactivity to GDF5 (CDMP-1), called the morphogenetic protein-1, cartilage-derived, in lingual squamous cell carcinoma.

  9. homozygous sequence variants in the GDF5 gene underlie acromesomelic dysplasia type-grebe in consanguineous families

  10. The prevention of IL-1Beta (zeige IL1B Antikörper)-induced nucleus pulposus extracellular matrix degeneration by miR-7 (zeige LILRB1 Antikörper) silencing was attenuated by GDF5 siRNA.

Mouse (Murine) Growth Differentiation Factor 5 (GDF5) Interaktionspartner

  1. spatiotemporal dynamics of Gdf5 expression may instruct lineage divergence.

  2. he large array of modular enhancers for Gdf5 provide a new foundation for studying the spatial specificity of joint patterning in vertebrates, as well as new candidates for regulatory regions that may also influence osteoarthritis risk in human population

  3. Mutant GDF5 enhances ameloblast differentiation via accelerated BMP2 (zeige BMP2 Antikörper)-induced Smad1 (zeige SMAD1 Antikörper)-Smad5 (zeige SMAD5 Antikörper)-Smad8 (zeige SMAD9 Antikörper) phosphorylation.

  4. Combined, these data suggest a possible pathway linking GDF5, ERG (zeige ERG Antikörper) and downstream factors in the processes of chondrocyte differentiation during articular joint formation.

  5. Growth differentiation factor 5 is a novel target-derived factor that promotes sympathetic axon growth and branching and makes a distinctive regional contribution to the establishment of sympathetic innervation.

  6. Dach2 (zeige DACH2 Antikörper) and Hdac9 (zeige HDAC9 Antikörper) mediate the effects of muscle activity on muscle reinnervation; Myog (zeige MYOG Antikörper) and Gdf5 appear to stimulate muscle reinnervation through parallel pathways

  7. Gdf-5 induced the expression of the alpha5 sub-unit, while Bmp-7 (zeige BMP7 Antikörper) induced the expression of the alphaV sub-unit.

  8. Clonal expansion of Gdf5 progenitors contributes to linear growth of the enthesis.

  9. GDF5 might play a critical role in 3T3-L1 preadipocyte differentiation

  10. These results suggest that PI3K/Akt (zeige AKT1 Antikörper) signals play a role in the GDF5-mediated brown adipogenesis through a mechanism related to activation of the Smad (zeige SMAD1 Antikörper) pathway.

Cow (Bovine) Growth Differentiation Factor 5 (GDF5) Interaktionspartner

  1. These results suggest that the SNP of the GDF5 gene could be a very useful genetic marker for body measurement traits in the bovine reproduction and breeding.

GDF5 Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Mutations in this gene are associated with acromesomelic dysplasia, Hunter-Thompson type\; brachydactyly, type C\; and chondrodysplasia, Grebe type. These associations confirm that the gene product plays a role in skeletal development.

Genbezeichner und Symbole assoziert mit GDF5

  • growth differentiation factor 5 L homeolog (gdf5.L) Antikörper
  • growth differentiation factor 5 (GDF5) Antikörper
  • growth differentiation factor 5 (Gdf5) Antikörper
  • BDA1C Antikörper
  • BMP14 Antikörper
  • bp Antikörper
  • brp Antikörper
  • Cdmp-1 Antikörper
  • Cdmp1 Antikörper
  • gdf Antikörper
  • gdf-5 Antikörper
  • GDF5 Antikörper
  • LAP4 Antikörper
  • OS5 Antikörper
  • SYM1B Antikörper
  • SYNS2 Antikörper

Bezeichner auf Proteinebene für GDF5

growth factor GDF5 , growth differentiation factor 5 , growth/differentiation factor 5-like , CDMP-1 , GDF-5 , cartilage-derived morphogenetic protein-1 , growth/differentiation factor 5 , radotermin , brachypodism , cartilage-derived morphogenetic protein 1 , growth differentiation factor 5 preproprotein , growth differentiation factor 5 (cartilage-derived morphogenetic protein-1)

GENE ID SPEZIES
446295 Xenopus laevis
100137480 Papio anubis
100393400 Callithrix jacchus
8200 Homo sapiens
14563 Mus musculus
252835 Rattus norvegicus
100328897 Oryctolagus cuniculus
100723808 Cavia porcellus
100520988 Sus scrofa
485850 Canis lupus familiaris
539559 Bos taurus
374249 Gallus gallus
101116499 Ovis aries
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