anti-Granzyme M (Lymphocyte Met-Ase 1) (GZMM) Antikörper

Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. Zusätzlich bieten wir Ihnen GZMM Kits (21) und GZMM Proteine (10) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GZMM 3004 P51124
GZMM 29252  
GZMM 16904  
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Top anti-GZMM Antikörper auf antikoerper-online.de

Showing 10 out of 42 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of GZMM Antibody (Center) in K562 cell line lysates (35 µg/lane). GZMM (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of GZMM Antibody (Center) (ABIN390763) in K562 cell line lysates (35 µg/lane). GZMM (arrow) was detected using the purified polyclonal antibody. GZMM Antibody (Center) (ABIN390763) IHC analysis in formalin fixed and paraffin embedded human lymph tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (37.73 KDa) . 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of Granzyme M expression in HeLa (A), PC12 (B), NS-1 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert ICC, IHC, IP, WB Western Blot; Sample: Human Jurkat cell lysate; Primary Ab: 1µg/ml Rabbit Anti-Human GZMM Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$316.00
Details
Maus Kaninchen Unkonjugiert ICC, IHC, IP, WB Figure.DAB staining on IHC-P. Samples: Mouse Tissue 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$324.00
Details
Ratte Kaninchen Unkonjugiert ICC, IHC, IP, WB Figure.DAB staining on IHC-P. Samples: Rat Tissue 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$342.00
Details
Human Maus Unkonjugiert ELISA, WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$450.00
Details
Human Kaninchen Unkonjugiert ELISA, WB   100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (38.1 KDa) . 50 μL Anmelden zum Anzeigen 11 bis 12 Tage
$305.71
Details

GZMM Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-GZMM Antikörper

  1. Human Monoclonal GZMM Primary Antibody für ELISA, WB - ABIN516325 : Schiffer, Letzian, Jost, Mladenov, Hristodorov, Huhn, Fischer, Barth, Thepen: Granzyme M as a novel effector molecule for human cytolytic fusion proteins: CD64-specific cytotoxicity of Gm-H22(scFv) against leukemic cells. in Cancer letters 2013 (PubMed)

Weitere Antikörper gegen GZMM Interaktionspartner

Human Granzyme M (Lymphocyte Met-Ase 1) (GZMM) Interaktionspartner

  1. GzMM has a critical role during early stages of inflammation in ulcerative colitis; in its absence colonic inflammation is enhanced.

  2. We also report that TNFalpha induces the attachment of Met1-linked Ub chains directly to TNF receptor 1, which do not seem to be attached covalently to Lys63-linked or other types of ubiquitin chain.

  3. Granzym M may be important in regulating HCMV latency and reactivation in SCT patients.

  4. GrM (zeige TPST2 Antikörper) is expressed in HCMV-specific CD8thorn T cells and cleaves host cell protein hnRNP K (zeige HNRNPK Antikörper) in the presence of RNA.

  5. FADD (zeige FADD Antikörper) cleavage by NK cell granzyme M enhances its self-association to facilitate procaspase-8 recruitment for auto-processing leading to caspase (zeige CASP3 Antikörper) cascade.

  6. Results indicate that cellular overexpression of SERPINB4 (zeige SERPINB4 Antikörper) inhibits recombinant GrM (zeige TPST2 Antikörper)-induced as well as NK cell-mediated cell death.

  7. GrM (zeige TPST2 Antikörper) also exists extracellularly in plasma where it could play a physiological role in controlling blood coagulation by determining plasma FVIII (zeige F8 Antikörper) levels via proteolytic processing of its carrier VWF (zeige VWF Antikörper).

  8. Results describe the structural characterization of granzyme M by molecular modeling as well as by detailed comparison with other granzymes.

  9. Noncytotoxic inhibition of cytomegalovirus replication through NK cell protease granzyme M-mediated cleavage of viral phosphoprotein 71.

  10. survivin (zeige BIRC5 Antikörper) cleavage by Granzyme M triggers degradation of the survivin (zeige BIRC5 Antikörper)-X-linked inhibitor of apoptosis protein (XIAP (zeige XIAP Antikörper)) complex to free caspase (zeige CASP3 Antikörper) activity leading to cytolysis of target tumor cells

Mouse (Murine) Granzyme M (Lymphocyte Met-Ase 1) (GZMM) Interaktionspartner

  1. GzMM has a critical role during early stages of inflammation in ulcerative colitis; in its absence colonic inflammation is enhanced.

  2. Granzyme M regulates the release of natural killer cell MIP-1alpha (zeige CCL3 Antikörper) to initiate innate immune responses.

  3. Natural killer (NK) cell GrzM augments the inflammatory cascade downstream of lipopolysaccharide (LPS (zeige TLR4 Antikörper))-toll (zeige TLR4 Antikörper)-like receptor (TLR)4 (zeige TLR4 Antikörper) signaling, which ultimately results in lethal endotoxicosis.

GZMM Antigen-Profil

Protein Überblick

Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectively termed granzymes and include 4 distinct gene products: granzyme A, granzyme B, granzyme H, and the protein encoded by this gene, granzyme M. Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit GZMM

  • granzyme M (LOC100136381) Antikörper
  • granzyme M (GZMM) Antikörper
  • granzyme M (Gzmm) Antikörper
  • granzyme M (lymphocyte met-ase 1) (Gzmm) Antikörper
  • Lmet1 Antikörper
  • MET1 Antikörper
  • MMET-1 Antikörper

Bezeichner auf Proteinebene für GZMM

granzyme M , HU-Met-1 , Met-1 serine protease , lymphocyte met-ase 1 , met-ase , natural killer cell granular protease , RNK-Met-1 , lymphoctye Met-ase 1

GENE ID SPEZIES
100136381 Salmo salar
3004 Homo sapiens
29252 Rattus norvegicus
16904 Mus musculus
100233186 Sus scrofa
Ausgewählte Anbieter für anti-GZMM (GZMM) Antikörper
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