Granulysin Proteine (GNLY)

The product of GNLY is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. Zusätzlich bieten wir Ihnen Granulysin Antikörper (78) und Granulysin Kits (18) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
GNLY 10578 P22749
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Showing 6 out of 8 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 46 Days
5.173,33 €
Details
HOST_NSO cells Human Unkonjugiert 4 pack Anmelden zum Anzeigen 6 bis 8 Tage
82,82 €
Details
HOST_Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 7 bis 8 Tage
345,60 €
Details
HOST_HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 6 bis 8 Tage
748,00 €
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HOST_Escherichia coli (E. coli) Human His tag   1 mg Anmelden zum Anzeigen 6 bis 8 Tage
4.379,05 €
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Human Unkonjugiert   2 μg Anmelden zum Anzeigen 10 bis 11 Tage
186,70 €
Details

GNLY Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
, ,

Am meisten referenzierte Granulysin Proteine

  1. Human GNLY Protein expressed in NSO cells - ABIN2666969 : Kalb, Glaser, Stary, Koszik, Stingl: TRAIL(+) human plasmacytoid dendritic cells kill tumor cells in vitro: mechanisms of imiquimod- and IFN-?-mediated antitumor reactivity. in Journal of immunology (Baltimore, Md. : 1950) 2012 (PubMed)
    Zeige alle 3 Referenzen für 2666969

Weitere Proteine zu Granulysin (GNLY) Interaktionspartnern

Human Granulysin (GNLY) Interaktionspartner

  1. These results suggest that the 15 kDa granulysin exhibits a novel mechanism in bacteria killing in a way that's different from most antimicrobial peptides.

  2. Decreased blood granulysin at the protein level, is linked to the immunological condition of latent tuberculosis infection.

  3. Carbamate pesticides significantly reduced the intracellular levels of perforin (zeige PRF1 Proteine), GrA (zeige NR3C1 Proteine), GrB, Gr3 (zeige PRLHR Proteine)/K, and GRN (zeige GRN Proteine) in NK-92CI cells.

  4. serum GNLY is closely associated with the clinical characteristics of nasopharyngeal carcinoma and may be a potential biomarker for nasopharyngeal carcinoma

  5. GNLY delivers Gzms into three protozoan parasites (Trypanosoma cruzi, Toxoplasma gondii and Leishmania major), in which the Gzms generate superoxide and inactivate oxidative defense enzymes to kill the parasite.

  6. Studies indicate that cytotoxic mechanisms mediated by granulysin and TRAIL (TNF-related apoptosis inducing ligand (zeige TNFSF10 Proteine)) seem to be less secondary effects on normal tissues.

  7. High Granulysin expression is associated with Cutaneous T Cell Lymphoma and Sezary Syndrome.

  8. A three-way interaction between SNPs in HLA-DQ and GNLY was identified in terms of HBV clearance.

  9. GNLY-expressing lymphocytes, probably attracted by IL-15 (zeige IL15 Proteine), not only participate partially in myocardial cell apoptosis, but also hasten resolution of cardiac leukocyte infiltration in patients with myocardial infarction.

  10. Serum granulysin levels were significantly elevated in both acute and chronic alopecia areata patients.

Cow (Bovine) Granulysin (GNLY) Interaktionspartner

  1. Intercaruncular epithelium granulysin may play important roles in the establishment and maintenance of gestation during normal pregnancy.

Granulysin (GNLY) Protein Überblick

Protein Überblick

The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells, which are released upon antigen stimulation. This protein is present in cytotoxic granules of cytotoxic T lymphocytes and natural killer cells, and it has antimicrobial activity against M. tuberculosis and other organisms. Alternatively spliced transcript variants encoding different isoforms have been identified.

Genbezeichner und Symbole assoziert mit Granulysin Proteine (GNLY)

  • granulysin (GNLY)
  • 519 Protein
  • D2S69E Protein
  • LAG-2 Protein
  • LAG2 Protein
  • NKG5 Protein
  • TLA519 Protein

Bezeichner auf Proteinebene für Granulysin Proteine (GNLY)

granulysin , T-cell activation protein 519 , T-lymphocyte activation gene 519 , lymphocyte-activation gene 2 , lymphokine LAG-2

GENE ID SPEZIES
459370 Pan troglodytes
100125622 Ovis aries
10578 Homo sapiens
404173 Bos taurus
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