anti-Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3) Antikörper

GGA3 encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. Zusätzlich bieten wir Ihnen GGA3 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GGA3 260302 Q8BMI3
GGA3 360658  
GGA3 23163 Q9NZ52
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Top anti-GGA3 Antikörper auf antikoerper-online.de

Showing 10 out of 63 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-GGA3 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Human Thymus 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$242.88
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB WB Image Sample (30 ug of whole cell lysate) A: A431 , 7.5% SDS PAGE antibody diluted at 1:2000 IHC-P Image Immunohistochemical analysis of paraffin-embedded Cal27 xenograft, using GGA3, antibody at 1:100 dilution. 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Hund Ziege Unkonjugiert ELISA   0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Human Maus Unkonjugiert IF, WB Western blot analysis of GGA3 on a Jurkat cell lysate (Human T-cell leukemia, ATCC TIB-152). Lane 1: 1:2500, lane 2: 1:5000, lane 3: 1:10,000 dilution of the mouse anti-human GGA3 antibody. Immunofluorescence staining of human endothelial cells. 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$168.74
Details
Schimpanse Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
$450.34
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Fledermaus Ziege Unkonjugiert IHC (p), ELISA Human Kidney (formalin-fixed, paraffin-embedded) stained with GGA3 antibody ABIN364247 at 2.5 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$451.00
Details
Hund Ziege Unkonjugiert EIA, IHC (p) Human Kidney (formalin-fixed, paraffin-embedded) stained with GGA3at 2.5 µg/ml followed by biotinylated anti-goat IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$500.50
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot using Affinity Purified anti-GGA3 antibody shows detection of a band at ~110 kDa corresponding to GFP-GGA3 fusion protein present in a lysate of HEK293 cells over- expressing the recombinant protein (lane 2, arrowhead). Pre-incubation of antibody with immunizing peptide blocks specific staining (lane 3). MW markers are shown in lane 1 (700 nm channel - red). Approximately 35 ?g of lysate was separated on a 16% Tricine gel by SDS-PAGE and transferred onto nitrocellulose. After blocking the membrane was probed with the primary antibody diluted to 1:600. Reaction occurred overnight at 4° C followed by washes and reaction with a 1:10,000 dilution of IRDye800 conjugated Gt-a-Rabbit IgG [H&L] (611-132-122) for 45 min at room temperature (800 nm channel - green). IRDye800 fluorescence image was captured using the Odyssey® Infrared Imaging System developed by LI-COR. IRDye is a trademark of LI-COR, Inc. Other detection systems will yield similar results. 100 μg Anmelden zum Anzeigen 1 bis 2 Tage
$389.00
Details

GGA3 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-GGA3 Antikörper

  1. Human Monoclonal GGA3 Primary Antibody für IF, WB - ABIN968815 : Boman, Zhang, Zhu, Kahn: A family of ADP-ribosylation factor effectors that can alter membrane transport through the trans-Golgi. in Molecular biology of the cell 2000 (PubMed)
    Show all 3 Pubmed References

  2. Dog (Canine) Polyclonal GGA3 Primary Antibody für ELISA - ABIN250865 : Prag, Lee, Mattera, Arighi, Beach, Bonifacino, Hurley: Structural mechanism for ubiquitinated-cargo recognition by the Golgi-localized, gamma-ear-containing, ADP-ribosylation-factor-binding proteins. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)

  3. Human Monoclonal GGA3 Primary Antibody für IF, WB - ABIN968814 : DellAngelica, Puertollano, Mullins, Aguilar, Vargas, Hartnell, Bonifacino: GGAs: a family of ADP ribosylation factor-binding proteins related to adaptors and associated with the Golgi complex. in The Journal of cell biology 2000 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen GGA3 Interaktionspartner

Mouse (Murine) Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3) Interaktionspartner

  1. GGA3 plays a key role in GABAergic transmission. GGA3 deletion results in decreased anxiety-like behaviors and increased BACE1 (zeige BACE Antikörper) levels.

  2. depletion of GGA1 (zeige GGA1 Antikörper) and GGA3 engender a rapid and robust elevation of BACE1 (zeige BACE Antikörper) in the acute phase after brain injury. However, the efficient disposal of the acutely accumulated BACE1 (zeige BACE Antikörper) solely depends on GGA3 levels in the subacute phase of injury

  3. GGA3 tightly and inversely regulate BACE1 levels via interaction with ubiquitin sorting machinery

Human Golgi-Associated, gamma Adaptin Ear Containing, ARF Binding Protein 3 (GGA3) Interaktionspartner

  1. In the absence of GGA3, integrins are increasingly retained inside the cell, traffic toward the perinuclear lysosomal compartment and their degradation is enhanced.

  2. This work identifies GGA3 as a key player in a novel DXXLL-mediated endosomal sorting machinery that targets TrkA (zeige NTRK1 Antikörper) to the plasma membrane, where it prolongs the activation of Akt (zeige AKT1 Antikörper) signaling and survival responses.

  3. role of GGA3 in the cell surface export of alpha2B (zeige ADRA2B Antikörper)-adrenergic receptor

  4. These data indicate that clathrin is required for the function of AP-1 (zeige FOSB Antikörper)- and GGA-coated carriers at the trans-Golgi network but may be dispensable for outward traffic en route to the plasma membrane.

  5. GGA3 is involved in the cellular processes relevant for Alzheimer's disease pathogenesis.

  6. Subcellular fractionation of Alzheimer's disease cortex with low levels of Golgi-localized GGA proteins shows an alteration of beta-secretase distribution and extensive co-localization with amyloid beta precursor protein APP (zeige APP Antikörper).

  7. GGA3 tightly and inversely regulate BACE1 levels via interaction with ubiquitin sorting machinery

  8. structures of the VHS domain of human GGA3 complexed with signals from both mannose-6-phosphate receptors

  9. These results indicate that GGA3-S is predominantly expressed in human tissues except the brain and in cell lines.

  10. RNAi of GGA3 expression results in accumulation of the cation-independent mannose 6-phosphate receptor (zeige IGF2R Antikörper) and internalized epidermal growth factor (EGF (zeige EGF Antikörper)) within enlarged early endosomes. This perturbation impairs the degradation of internalized EGF (zeige EGF Antikörper).

GGA3 Antigen-Profil

Protein Überblick

This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) family. This family includes ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants have been identified in this gene.

Genbezeichner und Symbole assoziert mit GGA3

  • golgi associated, gamma adaptin ear containing, ARF binding protein 3 (Gga3) Antikörper
  • golgi associated, gamma adaptin ear containing, ARF binding protein 3 (GGA3) Antikörper
  • C230037M19Rik Antikörper
  • mKIAA0154 Antikörper

Bezeichner auf Proteinebene für GGA3

ADP-ribosylation factor-binding protein GGA3 , golgi-localized, gamma ear-containing, ARF-binding protein 3 , Golgi-localized, gamma ear-containing, ARF-binding protein 3 , golgi associated, gamma adaptin ear containing, ARF binding protein 3 , ADP-ribosylation factor binding protein 3

GENE ID SPEZIES
260302 Mus musculus
360658 Rattus norvegicus
23163 Homo sapiens
483310 Canis lupus familiaris
454877 Pan troglodytes
100172741 Pongo abelii
100525777 Sus scrofa
510539 Bos taurus
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